Ser14
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Home > Phosphorylation Site Page: > Ser14  -  H2B (mouse)

Site Information
APAPkkGskkAVTkA   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 449904

In vivo Characterization
Methods used to characterize site in vivo:
immunoprecipitation ( 1 ) , phospho-antibody ( 1 , 2 , 3 ) , western blotting ( 1 , 3 )
Relevant cell line - cell type - tissue:

Upstream Regulation
Regulatory protein:
AID (mouse) ( 1 )
Putative in vivo kinases:
PKCD (mouse) ( 2 )
Treatments:
ionizing_radiation ( 3 ) , laser_treatment ( 3 ) , wortmannin ( 3 ) , Z-DEVD-fmk ( 3 )

Downstream Regulation
Effects of modification on H2B:
phosphorylation ( 1 )
Effects of modification on biological processes:
apoptosis, altered ( 2 )

References 

1

Odegard VH, et al. (2005) Histone modifications associated with somatic hypermutation. Immunity 23, 101-10
16039583   Curated Info

2

Mecklenbräuker I, et al. (2004) Regulation of B-cell survival by BAFF-dependent PKCdelta-mediated nuclear signalling. Nature 431, 456-61
15361883   Curated Info

3

Fernandez-Capetillo O, Allis CD, Nussenzweig A (2004) Phosphorylation of histone H2B at DNA double-strand breaks. J Exp Med 199, 1671-7
15197225   Curated Info