Thr494
Javascript is not enabled on this browser. This site will not work properly without Javascript.
PhosphoSitePlus Homepage PhosphoSitePlus® v6.6.0.2
Powered by Cell Signaling Technology
Home > Phosphorylation Site Page: > Thr494  -  PKCA (cow)

Site Information
EHMMDGVttRtFCGT   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 449889

In vivo Characterization
Methods used to characterize site in vivo:
[32P] bio-synthetic labeling ( 2 ) , immunoprecipitation ( 2 ) , mutation of modification site ( 1 , 2 ) , phospho-antibody ( 1 ) , western blotting ( 1 , 2 )
Relevant cell line - cell type - tissue:

Downstream Regulation
Effects of modification on PKCA:
enzymatic activity, induced ( 2 )

References 

1

Cazaubon S, Bornancin F, Parker PJ (1994) Threonine-497 is a critical site for permissive activation of protein kinase C alpha. Biochem J 301 ( Pt 2), 443-8
8042986   Curated Info

2

Cazaubon SM, Parker PJ (1993) Identification of the phosphorylated region responsible for the permissive activation of protein kinase C. J Biol Chem 268, 17559-63
8349635   Curated Info