Ser84
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Home > Phosphorylation Site Page: > Ser84  -  hnRNP A0 (mouse)

Site Information
VELKRAVsREDsARP   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 449874

In vivo Characterization
Methods used to characterize site in vivo:
mass spectrometry ( 1 , 2 , 3 ) , phospho-antibody ( 4 ) , western blotting ( 4 )
Relevant cell line - cell type - tissue:
'3T3-L1, differentiated' (adipocyte) ( 1 , 2 ) , macrophage-bone marrow ( 4 ) , macrophage-peritoneum [MPRIP (mouse), homozygous knockout] ( 3 ) , RAW 264 (macrophage) ( 4 )

Upstream Regulation
Putative in vivo kinases:
MAPKAPK2 (mouse) ( 4 )
Kinases, in vitro:
MAPKAPK2 (mouse) ( 4 )
Treatments:
insulin ( 2 ) , LPS ( 4 ) , PD184352 ( 4 ) , SB203580 ( 4 )

References 

1

Parker BL, et al. (2015) Targeted phosphoproteomics of insulin signaling using data-independent acquisition mass spectrometry. Sci Signal 8, rs6
26060331   Curated Info

2

Humphrey SJ, et al. (2013) Dynamic Adipocyte Phosphoproteome Reveals that Akt Directly Regulates mTORC2. Cell Metab 17, 1009-20
23684622   Curated Info

3

Wu X, et al. (2012) Investigation of receptor interacting protein (RIP3)-dependent protein phosphorylation by quantitative phosphoproteomics. Mol Cell Proteomics 11, 1640-51
22942356   Curated Info

4

Rousseau S, et al. (2002) Inhibition of SAPK2a/p38 prevents hnRNP A0 phosphorylation by MAPKAP-K2 and its interaction with cytokine mRNAs. EMBO J 21, 6505-14
12456657   Curated Info