Ser8
Javascript is not enabled on this browser. This site will not work properly without Javascript.
PhosphoSitePlus Homepage PhosphoSitePlus®
Powered by Cell Signaling Technology
Home > Phosphorylation Site Page: > Ser8  -  GYS2 (rat)

Site Information
MLRGRsLsVtsLGGL   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 484503

In vivo Characterization
Methods used to characterize site in vivo:
mass spectrometry ( 1 , 2 , 4 ) , mutation of modification site ( 3 ) , phospho-antibody ( 3 ) , western blotting ( 3 )
Relevant cell line - cell type - tissue:
adipose tissue ( 1 ) , hepatocyte-liver ( 3 ) , liver ( 1 , 2 , 4 ) , lung ( 1 ) , thymus ( 1 )

Upstream Regulation
Treatments:
glucose_starvation ( 3 )

Downstream Regulation
Effects of modification on GYS2:
enzymatic activity, inhibited ( 3 ) , intracellular localization ( 3 )

References 

1

Lundby A, et al. (2012) Quantitative maps of protein phosphorylation sites across 14 different rat organs and tissues. Nat Commun 3, 876
22673903   Curated Info

2

Demirkan G, et al. (2011) Phosphoproteomic Profiling of In Vivo Signaling in Liver by the Mammalian Target of Rapamycin Complex 1 (mTORC1). PLoS One 6, e21729
21738781   Curated Info

3

Ros S, et al. (2009) Control of liver glycogen synthase activity and intracellular distribution by phosphorylation. J Biol Chem 284, 6370-8
19124463   Curated Info

4

Moser K, White FM (2006) Phosphoproteomic analysis of rat liver by high capacity IMAC and LC-MS/MS. J Proteome Res 5, 98-104
16396499   Curated Info