Ser179

Site Information
MKKKDEGsYDLGKKP SwissProt Entrez-Gene
Blast this site against: NCBI SwissProt PDB
Site Group ID: 449863

In vivo Characterization
Methods used to characterize site in vivo:	[32P] bio-synthetic labeling ( 2 ) , phosphoamino acid analysis ( 2 ) , phosphopeptide mapping ( 2 )
Relevant cell line - cell type - tissue:	3T3 (fibroblast) [SHP-2 (mouse), homozygous knockout] ( 2 )

Upstream Regulation
Treatments:	calyculin_A ( 2 ) , chelerythrine ( 2 ) , FGF2 ( 2 ) , phorbol_ester ( 2 )

References
1	Finsen AV, et al. (2011) Syndecan-4 is essential for development of concentric myocardial hypertrophy via stretch-induced activation of the calcineurin-NFAT pathway. PLoS One 6, e28302 22164265 Curated Info
2	Horowitz A, Simons M (1998) Regulation of syndecan-4 phosphorylation in vivo. J Biol Chem 273, 10914-8 9556568 Curated Info