Tyr796

Site Information
GGTGGSVyTEDNDDD SwissProt Entrez-Gene
Blast this site against: NCBI SwissProt PDB
Site Group ID: 449861

In vivo Characterization
Methods used to characterize site in vivo:	[32P] bio-synthetic labeling ( 4 ) , immunoprecipitation ( 3 ) , mass spectrometry ( 1 , 2 ) , mutation of modification site ( 3 ) , phospho-antibody ( 3 ) , phosphopeptide mapping ( 4 )
Relevant cell line - cell type - tissue:	293 (epithelial) ( 3 ) , 3T3 (fibroblast) [SHP-2 (mouse), homozygous knockout] ( 3 ) , A431 (epithelial) ( 3 ) , BW125.1C (T lymphocyte) ( 4 ) , COS (fibroblast) ( 3 ) , HepG2 (hepatic) ( 3 ) , liver ( 1 , 2 ) , MDCK (epithelial) ( 3 ) , REF52 (fibroblast) ( 3 ) , Saos-2 (bone cell) ( 3 )

Upstream Regulation
Putative upstream phosphatases:	PTPN3 (human) ( 3 )

References
1	Guo A (2009) CST Curation Set: 7791; Year: 2009; Biosample/Treatment: tissue, liver(STK11)/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: RXXp[ST] Antibodies Used to Purify Peptides prior to LCMS: Phospho-(Ser/Thr) PKD Substrate Antibody Cat#: 4381, PTMScan(R) Phospho-PKD Substrate Motif (LXRXXpS/pT) Immunoaffinity Beads Cat#: 1986 Curated Info
2	Guo A (2009) CST Curation Set: 7792; Year: 2009; Biosample/Treatment: tissue, liver(STK11)/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: RXXp[ST] Antibodies Used to Purify Peptides prior to LCMS: Phospho-(Ser/Thr) PKD Substrate Antibody Cat#: 4381, PTMScan(R) Phospho-PKD Substrate Motif (LXRXXpS/pT) Immunoaffinity Beads Cat#: 1986 Curated Info
3	Zhang SH, Liu J, Kobayashi R, Tonks NK (1999) Identification of the cell cycle regulator VCP (p97/CDC48) as a substrate of the band 4.1-related protein-tyrosine phosphatase PTPH1. J Biol Chem 274, 17806-12 10364224 Curated Info
4	Egerton M, Samelson LE (1994) Biochemical characterization of valosin-containing protein, a protein tyrosine kinase substrate in hematopoietic cells. J Biol Chem 269, 11435-41 8157674 Curated Info