Ser165
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Home > Phosphorylation Site Page: > Ser165  -  HDGF (rat)

Site Information
AGDMLEDsPKRPKES   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 452720

In vivo Characterization
Methods used to characterize site in vivo:
mass spectrometry ( 1 , 2 , 3 , 5 , 6 , 7 , 8 )
Relevant cell line - cell type - tissue:
'brain, brainstem' ( 3 ) , 'brain, cerebellum' ( 3 ) , 'brain, cerebral cortex' ( 3 ) , 'kidney, inner medulla' ( 6 , 7 ) , adipose tissue ( 3 ) , blood ( 3 ) , heart ( 3 ) , IEC-6 (epithelial) ( 1 ) , intestine ( 3 ) , kidney ( 3 ) , liver ( 3 , 5 , 8 ) , lung ( 3 ) , muscle ( 3 ) , pancreas ( 3 ) , PC-12 (chromaffin) ( 2 ) , PC-12 (chromaffin) [TrkA (rat), transfection] ( 2 ) , spleen ( 3 ) , stomach ( 3 ) , testis ( 3 ) , thymus ( 3 )

Upstream Regulation
Treatments:
PDGF ( 2 ) , serum ( 1 )

References 

1

Courcelles M, et al. (2013) Phosphoproteome dynamics reveal novel ERK1/2 MAP kinase substrates with broad spectrum of functions. Mol Syst Biol 9, 669
23712012   Curated Info

2

Biarc J, Chalkley RJ, Burlingame AL, Bradshaw RA (2012) The induction of serine/threonine protein phosphorylations by a PDGFR/TrkA chimera in stably transfected PC12 cells. Mol Cell Proteomics 11, 15-30
22027198   Curated Info

3

Lundby A, et al. (2012) Quantitative maps of protein phosphorylation sites across 14 different rat organs and tissues. Nat Commun 3, 876
22673903   Curated Info

4

Everett AD, et al. (2011) Mitotic phosphorylation activates hepatoma-derived growth factor as a mitogen. BMC Cell Biol 12, 15
21489262   Curated Info

5

Demirkan G, et al. (2011) Phosphoproteomic Profiling of In Vivo Signaling in Liver by the Mammalian Target of Rapamycin Complex 1 (mTORC1). PLoS One 6, e21729
21738781   Curated Info

6

Hoffert JD, et al. (2007) An automated platform for analysis of phosphoproteomic datasets: application to kidney collecting duct phosphoproteins. J Proteome Res 6, 3501-8
17683130   Curated Info

7

Hoffert JD, et al. (2006) Quantitative phosphoproteomics of vasopressin-sensitive renal cells: regulation of aquaporin-2 phosphorylation at two sites. Proc Natl Acad Sci U S A 103, 7159-64
16641100   Curated Info

8

Moser K, White FM (2006) Phosphoproteomic analysis of rat liver by high capacity IMAC and LC-MS/MS. J Proteome Res 5, 98-104
16396499   Curated Info