Ser141
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Home > Phosphorylation Site Page: > Ser141  -  PAK2 (rabbit)

Site Information
TVKQKYLsFTPPEKD   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 448295

In vivo Characterization
Methods used to characterize site in vivo:
[32P] bio-synthetic labeling ( 2 ) , mutation of modification site ( 2 ) , phosphopeptide mapping ( 2 )
Relevant cell line - cell type - tissue:

Upstream Regulation
Kinases, in vitro:
PAK2 (rabbit) ( 1 , 3 )

Downstream Regulation
Effects of modification on PAK2:
enzymatic activity, induced ( 1 , 2 )
Inhibit interaction with:
CDC42 iso1 (human) ( 2 )

References 

1

Hsu YH, Johnson DA, Traugh JA (2008) Analysis of conformational changes during activation of protein kinase Pak2 by amide hydrogen/deuterium exchange. J Biol Chem 283, 36397-405
18984590   Curated Info

2

Jung JH, Traugh JA (2005) Regulation of the interaction of Pak2 with Cdc42 via autophosphorylation of serine 141. J Biol Chem 280, 40025-31
16204230   Curated Info

3

Gatti A, Huang Z, Tuazon PT, Traugh JA (1999) Multisite autophosphorylation of p21-activated protein kinase gamma-PAK as a function of activation. J Biol Chem 274, 8022-8
10075701   Curated Info