Tyr141
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Home > Phosphorylation Site Page: > Tyr141  -  ADRB2 (hamster)

Site Information
AITSPFKyQSLLTKN   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 449832

In vivo Characterization
Methods used to characterize site in vivo:
immunoprecipitation ( 1 ) , mutation of modification site ( 1 ) , phospho-antibody ( 1 ) , western blotting ( 1 )
Relevant cell line - cell type - tissue:
A431 (epithelial) ( 1 ) , CHO (fibroblast) [EphB1 (human), transfection] ( 1 )

Upstream Regulation
Kinases, in vitro:
INSR (human) ( 2 )
Treatments:
isoproterenol ( 1 )

References 

1

Fan G, Shumay E, Malbon CC, Wang H (2001) c-Src tyrosine kinase binds the beta 2-adrenergic receptor via phospho-Tyr-350, phosphorylates G-protein-linked receptor kinase 2, and mediates agonist-induced receptor desensitization. J Biol Chem 276, 13240-7
11278940   Curated Info

2

Baltensperger K, et al. (1996) The beta-adrenergic receptor is a substrate for the insulin receptor tyrosine kinase. J Biol Chem 271, 1061-4
8557631   Curated Info