Tyr350
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Home > Phosphorylation Site Page: > Tyr350  -  ADRB2 (human)

Site Information
RRssLKAyGNGyssN   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 449808

In vivo Characterization
Methods used to characterize site in vivo:
[32P] bio-synthetic labeling ( 4 ) , mutation of modification site ( 4 ) , phospho-antibody ( 1 ) , phosphoamino acid analysis ( 4 ) , western blotting ( 4 )
Relevant cell line - cell type - tissue:
'muscle, smooth' ( 1 ) , CHO (fibroblast) ( 4 ) , mast ( 1 )

Upstream Regulation
Treatments:
anti-CADM1 ( 1 ) , anti-SCF ( 1 ) , genistein ( 3 ) , SCF ( 3 )

References 

1

Lewis RJ, et al. (2016) Bidirectional Counterregulation of Human Lung Mast Cell and Airway Smooth Muscle β2 Adrenoceptors. J Immunol 196, 55-63
26608913   Curated Info

2

Nobles KN, et al. (2011) Distinct phosphorylation sites on the β(2)-adrenergic receptor establish a barcode that encodes differential functions of β-arrestin. Sci Signal 4, ra51
21868357   Curated Info

3

Cruse G, et al. (2010) Counterregulation of beta(2)-adrenoceptor function in human mast cells by stem cell factor. J Allergy Clin Immunol 125, 257-63.e1-5
19864009   Curated Info

4

Valiquette M, Parent S, Loisel TP, Bouvier M (1995) Mutation of tyrosine-141 inhibits insulin-promoted tyrosine phosphorylation and increased responsiveness of the human beta 2-adrenergic receptor. EMBO J 14, 5542-9
8521811   Curated Info