Tyr14
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Home > Phosphorylation Site Page: > Tyr14  -  caveolin-1 (dog)

Site Information
VDSEGHLyTVPIREQ   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 448422

In vivo Characterization
Methods used to characterize site in vivo:
flow cytometry ( 1 ) , mutation of modification site ( 1 ) , phospho-antibody ( 1 , 2 ) , western blotting ( 1 , 2 )
Relevant cell line - cell type - tissue:

Upstream Regulation
Treatments:
cholesterol ( 2 ) , dIgA ( 2 ) , methyl-beta-cyclodextrin ( 2 ) , transferrin ( 2 )

Downstream Regulation
Effects of modification on caveolin-1:
molecular association, regulation ( 1 )
Effects of modification on biological processes:
cell adhesion, induced ( 1 ) , cell motility, induced ( 1 )

References 

1

Ortiz R, et al. (2016) Extracellular matrix-specific Caveolin-1 phosphorylation on tyrosine 14 is linked to augmented melanoma metastasis but not tumorigenesis. Oncotarget 7, 40571-40593
27259249   Curated Info

2

Leyt J, et al. (2007) Cholesterol-sensitive modulation of transcytosis. Mol Biol Cell 18, 2057-71
17392516   Curated Info