Ser47

Site Information
RVGsssssFRGSMGT SwissProt Entrez-Gene
Blast this site against: NCBI SwissProt PDB
Site Group ID: 484005

In vivo Characterization
Methods used to characterize site in vivo:	2D analysis ( 4 ) , immunoprecipitation ( 4 ) , mass spectrometry ( 1 , 2 , 3 , 4 ) , phospho-antibody ( 4 ) , western blotting ( 4 )
Relevant cell line - cell type - tissue:	GH4C1 (pituitary cell) ( 4 ) , liver ( 1 , 2 ) , liver [leptin (mouse), homozygous knockout] ( 2 ) , mpkCCD (renal) ( 3 )

Upstream Regulation
Kinases, in vitro:	PKCE (human) ( 4 )

References
1	Robles MS, Humphrey SJ, Mann M (2017) Phosphorylation Is a Central Mechanism for Circadian Control of Metabolism and Physiology. Cell Metab 25, 118-127 27818261 Curated Info
2	Grimsrud PA, et al. (2012) A quantitative map of the liver mitochondrial phosphoproteome reveals posttranslational control of ketogenesis. Cell Metab 16, 672-83 23140645 Curated Info
3	Rinschen MM, et al. (2010) Quantitative phosphoproteomic analysis reveals vasopressin V2-receptor-dependent signaling pathways in renal collecting duct cells. Proc Natl Acad Sci U S A 107, 3882-7 20139300 Curated Info
4	Akita Y, et al. (2007) Protein kinase C epsilon phosphorylates keratin 8 at Ser8 and Ser23 in GH4C1 cells stimulated by thyrotropin-releasing hormone. FEBS J 274, 3270-85 17553064 Curated Info