Thr2314
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Home > Phosphorylation Site Page: > Thr2314  -  NG2 (rat)

Site Information
ELLQFCRtPNPALRN   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 483998

In vivo Characterization
Methods used to characterize site in vivo:
immunoprecipitation ( 1 ) , phospho-antibody ( 1 ) , western blotting ( 1 )
Disease tissue studied:
brain cancer ( 1 ) , glioblastoma ( 1 ) , glioma ( 1 ) , melanoma skin cancer ( 1 )
Relevant cell line - cell type - tissue:

Upstream Regulation
Regulatory protein:
MEK1 (human) ( 1 )
Putative in vivo kinases:
ERK1 (human) ( 1 ) , ERK2 (human) ( 1 )
Kinases, in vitro:
ERK2 (mouse) ( 1 )
Treatments:
PDGF ( 1 ) , U0126 ( 1 )

Downstream Regulation
Effects of modification on NG2:
intracellular localization ( 1 )
Effects of modification on biological processes:
cell growth, altered ( 1 )

References 

1

Makagiansar IT, Williams S, Mustelin T, Stallcup WB (2007) Differential phosphorylation of NG2 proteoglycan by ERK and PKCalpha helps balance cell proliferation and migration. J Cell Biol 178, 155-65
17591920   Curated Info