Ser183
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Home > Phosphorylation Site Page: > Ser183  -  RALA (human)

Site Information
RARKMEDsKEKNGKK   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 483988

In vivo Characterization
Methods used to characterize site in vivo:
mass spectrometry ( 2 ) , mutation of modification site ( 1 , 2 ) , phospho-antibody ( 2 ) , western blotting ( 2 )
Disease tissue studied:
lung cancer ( 2 ) , non-small cell lung cancer ( 2 ) , non-small cell lung adenocarcinoma ( 2 )
Relevant cell line - cell type - tissue:

Upstream Regulation
Putative upstream phosphatases:
PPP2CA (human) ( 2 )

Downstream Regulation
Effects of modification on RALA:
enzymatic activity, induced ( 2 )
Effects of modification on biological processes:
carcinogenesis, induced ( 2 ) , cell growth, induced ( 2 )

References 

1

Pollock SR, et al. (2019) RalA and RalB relocalization to depolarized mitochondria depends on clathrin-mediated endocytosis and facilitates TBK1 activation. PLoS One 14, e0214764
30995277   Curated Info

2

Sablina AA, et al. (2007) The tumor suppressor PP2A Abeta regulates the RalA GTPase. Cell 129, 969-82
17540176   Curated Info