Thr51
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Home > Phosphorylation Site Page: > Thr51  -  ATF-2 (rat)

Site Information
SVIVADQtPtPtRFL   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 448224

In vivo Characterization
Methods used to characterize site in vivo:
mass spectrometry ( 1 , 2 , 3 ) , phospho-antibody ( 4 )
Relevant cell line - cell type - tissue:
adipose tissue ( 2 ) , IEC-6 (epithelial) ( 1 ) , kidney ( 2 ) , liver ( 2 , 3 ) , lung ( 2 ) , PC-12 (chromaffin) ( 4 ) , spleen ( 2 )

Upstream Regulation
Regulatory protein:
MTPN (human) ( 4 )
Treatments:
colforsin ( 4 ) , NGF ( 4 )

References 

1

Courcelles M, et al. (2013) Phosphoproteome dynamics reveal novel ERK1/2 MAP kinase substrates with broad spectrum of functions. Mol Syst Biol 9, 669
23712012   Curated Info

2

Lundby A, et al. (2012) Quantitative maps of protein phosphorylation sites across 14 different rat organs and tissues. Nat Commun 3, 876
22673903   Curated Info

3

Demirkan G, et al. (2011) Phosphoproteomic Profiling of In Vivo Signaling in Liver by the Mammalian Target of Rapamycin Complex 1 (mTORC1). PLoS One 6, e21729
21738781   Curated Info

4

Suzuki T, Yamakuni T, Hagiwara M, Ichinose H (2002) Identification of ATF-2 as a transcriptional regulator for the tyrosine hydroxylase gene. J Biol Chem 277, 40768-74
12196528   Curated Info

5

Livingstone C, Patel G, Jones N (1995) ATF-2 contains a phosphorylation-dependent transcriptional activation domain. EMBO J 14, 1785-97
7737129   Curated Info