Ser233
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Home > Phosphorylation Site Page: > Ser233  -  UBC3B (human)

Site Information
DCYDDDDsGNEEs__   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 449751

In vivo Characterization
Methods used to characterize site in vivo:
[32P] bio-synthetic labeling ( 2 ) , mass spectrometry ( 1 ) , mutation of modification site ( 2 ) , western blotting ( 2 )
Relevant cell line - cell type - tissue:

Upstream Regulation
Putative in vivo kinases:
CK2A1 (human) ( 2 )
Kinases, in vitro:
CK2A1 (human) ( 2 )
Treatments:
TBB ( 2 )

Downstream Regulation
Effects of modification on UBC3B:
molecular association, regulation ( 2 )
Effects of modification on biological processes:
transcription, altered ( 2 )
Induce interaction with:
BRD8 iso2 (human) ( 2 )

References 

1

Dephoure N, et al. (2008) A quantitative atlas of mitotic phosphorylation. Proc Natl Acad Sci U S A 105, 10762-7
18669648   Curated Info

2

Semplici F, Meggio F, Pinna LA, Oliviero S (2002) CK2-dependent phosphorylation of the E2 ubiquitin conjugating enzyme UBC3B induces its interaction with beta-TrCP and enhances beta-catenin degradation. Oncogene 21, 3978-87
12037680   Curated Info