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Site Information |
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sHEDLPAsQERSEVN SwissProt Entrez-Gene |
Blast this site against: NCBI SwissProt PDB |
Site Group ID: 481705 |
In vivo Characterization | |
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Methods used to characterize site in vivo: | |
Disease tissue studied: | |
Relevant cell line - cell type - tissue: |
Upstream Regulation | |
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Putative in vivo kinases: | |
Kinases, in vitro: | |
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Downstream Regulation | |
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Effects of modification on BUB1: | |
Effects of modification on biological processes: |
References | |
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Stuart SA, et al. (2015) A Phosphoproteomic Comparison of B-RAFV600E and MKK1/2 Inhibitors in Melanoma Cells. Mol Cell Proteomics 14, 1599-615
25850435 Curated Info |
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Asghar A, et al. (2015) Bub1 autophosphorylation feeds back to regulate kinetochore docking and promote localized substrate phosphorylation. Nat Commun 6, 8364
26399325 Curated Info |
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Yang C, et al. (2014) ATM-mediated Mad1 Serine 214 phosphorylation regulates Mad1 dimerization and the spindle assembly checkpoint. Carcinogenesis 35, 2007-13
24728176 Curated Info |
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Beli P, et al. (2012) Proteomic Investigations Reveal a Role for RNA Processing Factor THRAP3 in the DNA Damage Response. Mol Cell 46, 212-25
22424773 Curated Info |
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Yang C, et al. (2012) The kinetochore protein Bub1 participates in the DNA damage response. DNA Repair (Amst) 11, 185-91
22071147 Curated Info |
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Yang C, et al. (2011) Aurora-B Mediated ATM Serine 1403 Phosphorylation Is Required for Mitotic ATM Activation and the Spindle Checkpoint. Mol Cell 44, 597-608
22099307 Curated Info |
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Oppermann FS, et al. (2009) Large-scale proteomics analysis of the human kinome. Mol Cell Proteomics 8, 1751-64
19369195 Curated Info |
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Matsuoka S, et al. (2007) ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage. Science 316, 1160-6
17525332 Curated Info |