Tyr161
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Home > Phosphorylation Site Page: > Tyr161  -  BIM (mouse)

Site Information
GDEFNETyTRRVFAN   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 810853200

In vivo Characterization
Methods used to characterize site in vivo:
immunoprecipitation ( 1 ) , mutation of modification site ( 1 ) , phospho-antibody ( 1 ) , western blotting ( 1 )
Relevant cell line - cell type - tissue:
293 (epithelial) ( 1 ) , HeLa (cervical) ( 1 ) , MEF (fibroblast) ( 1 )

Upstream Regulation
Kinases, in vitro:
LYN (human) ( 1 )

Downstream Regulation
Effects of modification on BIM:
protein stabilization ( 1 )
Effects of modification on biological processes:
apoptosis, inhibited ( 1 )

References 

1

Aira LE, et al. (2018) The oncogenic tyrosine kinase Lyn impairs the pro-apoptotic function of Bim. Oncogene
29391601   Curated Info