Thr454
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Home > Phosphorylation Site Page: > Thr454  -  CTNND2 (mouse)

Site Information
tGTFRtstAPssPGV   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 480958

In vivo Characterization
Methods used to characterize site in vivo:
immunoprecipitation ( 3 ) , mass spectrometry ( 1 , 2 ) , mutation of modification site ( 3 )
Relevant cell line - cell type - tissue:
'neuron, hippocampal'-brain ( 3 ) , 3T3 (fibroblast) ( 3 ) , brain ( 2 ) , MEF (fibroblast) ( 3 ) , neuron:postsynaptic density-'brain, hippocampus, CA1 region' ( 1 )

Upstream Regulation
Kinases, in vitro:
Akt1 (human) ( 3 )

Downstream Regulation
Effects of modification on CTNND2:
molecular association, regulation ( 3 )
Effects of modification on biological processes:
cytoskeletal reorganization ( 3 )
Induce interaction with:
RGNEF (mouse) ( 3 )

References 

1

Li J, et al. (2016) Long-term potentiation modulates synaptic phosphorylation networks and reshapes the structure of the postsynaptic interactome. Sci Signal 9, rs8
27507650   Curated Info

2

Huttlin EL, et al. (2010) A tissue-specific atlas of mouse protein phosphorylation and expression. Cell 143, 1174-89
21183079   Curated Info

3

Kim H, et al. (2008) Delta-catenin-induced dendritic morphogenesis. An essential role of p190RhoGEF interaction through Akt1-mediated phosphorylation. J Biol Chem 283, 977-87
17993462   Curated Info