Thr636
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Home > Phosphorylation Site Page: > Thr636  -  BRAF iso1 (mouse)

Site Information
IGDFGLAtVKsRWsG   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 447807

In vivo Characterization
Methods used to characterize site in vivo:
mutation of modification site ( 1 )
Disease tissue studied:
breast adenocarcinoma ( 1 )
Relevant cell line - cell type - tissue:
mammary gland ( 1 ) , MMTV-PyMT (breast cell) ( 1 )

Downstream Regulation
Effects of modification on BRAF iso1:
activity, induced ( 1 ) , phosphorylation ( 1 )
Effects of modification on biological processes:
carcinogenesis, induced ( 1 ) , signaling pathway regulation ( 1 )

Disease / Diagnostics Relevance
Relevant diseases:
breast cancer ( 1 )

References 

1

Köhler M, et al. (2019) B-Raf deficiency impairs tumor initiation and progression in a murine breast cancer model. Oncogene 38, 1324-1339
30659267   Curated Info

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