Thr290
Javascript is not enabled on this browser. This site will not work properly without Javascript.
PhosphoSitePlus Homepage PhosphoSitePlus® v6.5.9.1
Powered by Cell Signaling Technology
Home > Phosphorylation Site Page: > Thr290  -  CXADR (human)

Site Information
PPkSRtStARsyIGs   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 801662702

In vivo Characterization
Methods used to characterize site in vivo:
immunoprecipitation ( 1 ) , mutation of modification site ( 1 ) , phospho-antibody ( 1 ) , western blotting ( 1 )
Disease tissue studied:
lung cancer ( 1 ) , non-small cell lung cancer ( 1 ) , non-small cell lung adenocarcinoma ( 1 )
Relevant cell line - cell type - tissue:

Upstream Regulation
Regulatory protein:
PKCD (human) ( 1 )
Treatments:
EGF ( 1 )

Downstream Regulation
Effects of modification on CXADR:
intracellular localization ( 1 ) , molecular association, regulation ( 1 )
Induce interaction with:
KIF22 (human) ( 1 )

References 

1

Pike R, et al. (2018) KIF22 coordinates CAR and EGFR dynamics to promote cancer cell proliferation. Sci Signal 11
29382784   Curated Info