Ser353
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Home > Phosphorylation Site Page: > Ser353  -  CXCR4 (mouse)

Site Information
sVsTESEsssFHSs_   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 7997136

In vivo Characterization
Methods used to characterize site in vivo:
mutation of modification site ( 1 ) , phospho-antibody ( 1 ) , western blotting ( 1 )
Relevant cell line - cell type - tissue:

Upstream Regulation
Regulatory protein:
CXCR4 (human) ( 1 )
Putative in vivo kinases:
GRK2 (human) ( 1 ) , GRK3 (human) ( 1 )
Treatments:
CXCL12 ( 1 ) , EGF ( 1 ) , NKH_477 ( 1 ) , phorbol_ester ( 1 ) , siRNA ( 1 ) , staurosporine ( 1 )

Downstream Regulation
Effects of modification on CXCR4:
phosphorylation ( 1 ) , receptor desensitization, inhibited ( 1 ) , receptor internalization, induced ( 1 )

References 

1

Mueller W, et al. (2013) Hierarchical organization of multi-site phosphorylation at the CXCR4 C terminus. PLoS One 8, e64975
23734232   Curated Info