Ser266

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Home > Phosphorylation Site Page: > Ser266 - SREBP-1 iso4 (mouse)

Site Information
IEKRYRssINDKIVE SwissProt Entrez-Gene
Blast this site against: NCBI SwissProt PDB
Site Group ID: 458357

In vivo Characterization
Methods used to characterize site in vivo:	mutation of modification site ( 1 ) , western blotting ( 1 )
Disease tissue studied:	liver cancer ( 1 )
Relevant cell line - cell type - tissue:	HepG2 (hepatic) ( 1 )

Downstream Regulation
Effects of modification on SREBP-1 iso4:	molecular association, regulation ( 1 )
Effects of modification on biological processes:	transcription, altered ( 1 )
Inhibit interaction with:	DNA ( 1 )

References
1	Yoon YS, et al. (2009) Salt-inducible kinase regulates hepatic lipogenesis by controlling SREBP-1c phosphorylation. J Biol Chem 284, 10446-52 19244231 Curated Info

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