Thr366
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Home > Phosphorylation Site Page: > Thr366  -  PTEN (mouse)

Site Information
ASSSTSVtPDVsDNE   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 449634

In vivo Characterization
Methods used to characterize site in vivo:
mass spectrometry (in vitro) ( 1 ) , mutation of modification site ( 1 ) , phospho-antibody ( 1 ) , western blotting ( 1 )
Relevant cell line - cell type - tissue:
HEK293T (epithelial) ( 1 ) , MEF (fibroblast) ( 1 )

Upstream Regulation
Putative in vivo kinases:
GSK3B (mouse) ( 1 )
Treatments:
lithium ( 1 )

Downstream Regulation
Effects of modification on PTEN:
protein stabilization ( 1 )

References 

1

Xu D, et al. (2010) Regulation of PTEN stability and activity by Plk3. J Biol Chem 285, 39935-42
20940307   Curated Info