Ser129
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Home > Phosphorylation Site Page: > Ser129  -  BAD (rat)

Site Information
EGMEEELsPFRGRsR   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 447861

In vivo Characterization
Methods used to characterize site in vivo:
mutation of modification site ( 1 ) , phospho-antibody ( 1 )
Relevant cell line - cell type - tissue:
'neuron, cerebellar granule'-brain ( 1 )

Upstream Regulation
Putative in vivo kinases:
CDK1 (rat) ( 1 )
Kinases, in vitro:
CDK1 (rat) ( 1 )
Treatments:
KCl_withdrawal ( 1 ) , nimodipine ( 1 ) , seliciclib ( 1 )

Downstream Regulation
Effects of modification on BAD:
molecular association, regulation ( 1 )
Effects of modification on biological processes:
apoptosis, induced ( 1 )
Inhibit interaction with:
14-3-3 zeta (human) ( 1 )

References 

1

Konishi Y, Lehtinen M, Donovan N, Bonni A (2002) Cdc2 phosphorylation of BAD links the cell cycle to the cell death machinery. Mol Cell 9, 1005-16
12049737   Curated Info