Ser462
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Home > Phosphorylation Site Page: > Ser462  -  CTPS (human)

Site Information
tLFQTkNsVMRkLYG   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 479852

In vivo Characterization
Methods used to characterize site in vivo:
[32P] bio-synthetic labeling ( 1 ) , mutation of modification site ( 1 ) , phosphopeptide mapping ( 1 )
Relevant cell line - cell type - tissue:
yeast cell ( 1 )

Upstream Regulation
Putative in vivo kinases:
PKCA (human) ( 1 )
Kinases, in vitro:
PKCA (human) ( 1 )

Downstream Regulation
Effects of modification on CTPS:
enzymatic activity, induced ( 1 )
Effects of modification on biological processes:
cell growth, altered ( 1 )

References 

1

Chang YF, Martin SS, Baldwin EP, Carman GM (2007) Phosphorylation of human CTP synthetase 1 by protein kinase C: identification of Ser(462) and Thr(455) as major sites of phosphorylation. J Biol Chem 282, 17613-22
17463002   Curated Info