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Site Information |
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NTVQDPAsMRDVGGM SwissProt Entrez-Gene |
Blast this site against: NCBI SwissProt PDB |
Site Group ID: 449609 |
In vivo Characterization | |
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Methods used to characterize site in vivo: | |
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Upstream Regulation | |
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Downstream Regulation | |
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Effects of modification on KOR-1: | |
Effects of modification on biological processes: |
References | |
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Schattauer SS, et al. (2019) Reactive oxygen species (ROS) generation is stimulated by κ opioid receptor activation through phosphorylated c-Jun N-terminal kinase and inhibited by p38 mitogen-activated protein kinase (MAPK) activation. J Biol Chem 294, 16884-16896
31575661 Curated Info |
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Lemos JC, Roth CA, Chavkin C (2011) Signaling Events Initiated by Kappa Opioid Receptor Activation: Quantification and Immunocolocalization Using Phospho-Selective KOR, p38 MAPK, and K(IR) 3.1 Antibodies. Methods Mol Biol 717, 197-219
21370032 Curated Info |
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Bruchas MR, Macey TA, Lowe JD, Chavkin C (2006) Kappa opioid receptor activation of p38 MAPK is GRK3- and arrestin-dependent in neurons and astrocytes. J Biol Chem 281, 18081-9
16648139 Curated Info |
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McLaughlin JP, Xu M, Mackie K, Chavkin C (2003) Phosphorylation of a carboxyl-terminal serine within the kappa-opioid receptor produces desensitization and internalization. J Biol Chem 278, 34631-40
12815037 Curated Info |