Ser105
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Home > Phosphorylation Site Page: > Ser105  -  GATA4 (human)

Site Information
AYTPPPVsPRFsFPG   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 449604

In vivo Characterization
Methods used to characterize site in vivo:
[32P] ATP in vitro ( 1 ) , mutation of modification site ( 1 ) , phospho-antibody ( 1 ) , western blotting ( 1 )
Relevant cell line - cell type - tissue:
HeLa (cervical) ( 1 )

Upstream Regulation
Regulatory protein:
CCND1 (human) ( 1 )
Putative in vivo kinases:
CDK4 (human) ( 1 )
Kinases, in vitro:
CDK4 (human) ( 1 )
Treatments:
PD0332991 ( 1 )

Downstream Regulation
Effects of modification on GATA4:
protein degradation ( 1 )
Effects of modification on biological processes:
cell differentiation, inhibited ( 1 ) , cell growth, induced ( 1 )

References 

1

Nakajima K, et al. (2011) Coordinated regulation of differentiation and proliferation of embryonic cardiomyocytes by a jumonji (Jarid2)-cyclin D1 pathway. Development 138, 1771-82
21447557   Curated Info

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