Ser44
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Home > Phosphorylation Site Page: > Ser44  -  BIM iso2 (human)

Site Information
QTEPQDRsPAPMSCD   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 449602

In vivo Characterization
Methods used to characterize site in vivo:
[32P] bio-synthetic labeling ( 2 ) , electrophoretic mobility shift ( 2 ) , mass spectrometry (in vitro) ( 1 ) , mutation of modification site ( 2 ) , phosphoamino acid analysis ( 2 )
Relevant cell line - cell type - tissue:

Upstream Regulation
Putative in vivo kinases:
JNK1 (human) ( 2 )
Kinases, in vitro:
CDK1 (human) ( 1 ) , JNK1 (human) ( 2 )
Treatments:
UV ( 2 )

References 

1

Mac Fhearraigh S, Mc Gee MM (2011) Cyclin B1 interacts with the BH3-only protein Bim and mediates its phosphorylation by Cdk1 during mitosis. Cell Cycle 10, 3886-96
22071694   Curated Info

2

Lei K, Davis RJ (2003) JNK phosphorylation of Bim-related members of the Bcl2 family induces Bax-dependent apoptosis. Proc Natl Acad Sci U S A 100, 2432-7
12591950   Curated Info