Tyr182
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Home > Phosphorylation Site Page: > Tyr182  -  TGFBR1 (human)

Site Information
TtLkDLIyDMttsGs   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 7791190

In vivo Characterization
Methods used to characterize site in vivo:
mutation of modification site ( 1 ) , phospho-antibody ( 1 )
Disease tissue studied:
prostate cancer ( 1 )
Relevant cell line - cell type - tissue:

Upstream Regulation
Putative in vivo kinases:
TGFBR2 ( 1 )

Downstream Regulation
Effects of modification on TGFBR1:
molecular association, regulation ( 1 )
Induce interaction with:
Src (human) ( 1 )

References 

1

Yakymovych I, et al. (2022) The type II TGF-β receptor phosphorylates Tyr in the type I receptor to activate downstream Src signaling. Sci Signal 15, eabp9521
36378749   Curated Info