Thr1483
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Home > Phosphorylation Site Page: > Thr1483  -  MEKK4 (mouse)

Site Information
KLKNNAQtMPGEVNS   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 479428

In vivo Characterization
Methods used to characterize site in vivo:
immunoprecipitation ( 1 ) , mass spectrometry ( 1 , 2 ) , multiple reaction monitoring (MRM) ( 1 ) , phospho-antibody ( 1 ) , western blotting ( 1 )
Relevant cell line - cell type - tissue:
'3T3-L1, differentiated' (adipocyte) ( 2 ) , 'muscle, skeletal' ( 1 )

Downstream Regulation
Effects of modification on MEKK4:
enzymatic activity, induced ( 1 ) , molecular association, regulation ( 1 )
Induce interaction with:
GADD45A (mouse) ( 1 )

References 

1

Bullard SA, et al. (2016) Gadd45a Protein Promotes Skeletal Muscle Atrophy by Forming a Complex with the Protein Kinase MEKK4. J Biol Chem 291, 17496-509
27358404   Curated Info

2

Humphrey SJ, et al. (2013) Dynamic Adipocyte Phosphoproteome Reveals that Akt Directly Regulates mTORC2. Cell Metab 17, 1009-20
23684622   Curated Info