Tyr95
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Home > Phosphorylation Site Page: > Tyr95  -  PRKD1 (human)

Site Information
KFPECGFyGMYDKIL   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 764000

In vivo Characterization
Methods used to characterize site in vivo:
immunoprecipitation ( 1 ) , mutation of modification site ( 1 , 2 ) , phospho-antibody ( 1 , 2 ) , western blotting ( 1 , 2 )
Relevant cell line - cell type - tissue:
HeLa (cervical) ( 1 , 2 )

Upstream Regulation
Putative in vivo kinases:
Src (human) ( 2 )
Treatments:
H2O2 ( 2 ) , phorbol_ester ( 2 ) , PP2 ( 2 )

Downstream Regulation
Effects of modification on PRKD1:
enzymatic activity, induced ( 2 ) , molecular association, regulation ( 2 )
Induce interaction with:
PKCD (human) ( 2 )

References 

1

Durand N, et al. (2017) Src-mediated tyrosine phosphorylation of Protein Kinase D2 at focal adhesions regulates cell adhesion. Sci Rep 7, 9524
28842658   Curated Info

2

Döppler H, Storz P (2007) A novel tyrosine phosphorylation site in protein kinase D contributes to oxidative stress-mediated activation. J Biol Chem 282, 31873-81
17804414   Curated Info

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