Tyr1176

Site Information
LDGEVTPyANTNNNA SwissProt Entrez-Gene
Blast this site against: NCBI SwissProt PDB
Site Group ID: 449557

In vivo Characterization
Methods used to characterize site in vivo:	[32P] bio-synthetic labeling ( 2 ) , immunoprecipitation ( 2 ) , phospho-antibody ( 1 , 2 ) , western blotting ( 1 , 2 )
Relevant cell line - cell type - tissue:	endothelial-aorta ( 1 ) , platelet-blood ( 2 )

Upstream Regulation
Putative in vivo kinases:	FAK (human) ( 2 )
Treatments:	AG490 ( 2 ) , G-1 ( 1 ) , geldanamycin ( 2 ) , herbimycin_A ( 2 ) , lavendustin_A ( 2 ) , PP2 ( 2 ) , RGDS ( 2 ) , thrombin ( 2 )

References
1	Tran QK, et al. (2015) Hetero-oligomeric Complex between the G Protein-coupled Estrogen Receptor 1 and the Plasma Membrane Ca2+-ATPase 4b. J Biol Chem 290, 13293-307 25847233 Curated Info
2	Wan TC, Zabe M, Dean WL (2003) Plasma membrane Ca2+-ATPase isoform 4b is phosphorylated on tyrosine 1176 in activated human platelets. Thromb Haemost 89, 122-31 12540962 Curated Info