Tyr205
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Site Information
HtGFLtEyVAtRWyR   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 447543
Associated spectra:  2 CST

In vivo Characterization
Methods used to characterize site in vivo:
[32P] bio-synthetic labeling ( 420 , 439 , 453 , 513 ) , flow cytometry ( 102 , 158 , 308 ) , immunoprecipitation ( 17 , 19 , 23 , 47 , 52 , 143 , 188 , 200 , 211 , 518 ) , mass spectrometry ( 15 , 18 , 28 , 39 , 54 , 55 , 56 , 57 , 60 , 65 , 68 , 69 , 71 , 72 , 74 , 79 , 80 , 81 , 82 , 83 , 84 , 85 , 96 , 97 , 121 , 133 , 134 , 135 , 136 , 139 , 145 , 146 , 147 , 148 , 149 , 156 , 157 , 160 , 161 , 162 , 163 , 164 , 165 , 166 , 167 , 168 , 169 , 170 , 171 , 172 , 173 , 176 , 177 , 178 , 180 , 181 , 182 , 183 , 184 , 185 , 191 , 192 , 193 , 194 , 195 , 196 , 205 , 206 , 207 , 208 , 209 , 216 , 217 , 218 , 219 , 220 , 224 , 226 , 227 , 228 , 229 , 230 , 231 , 232 , 233 , 234 , 235 , 236 , 237 , 238 , 239 , 240 , 241 , 242 , 243 , 244 , 245 , 246 , 247 , 249 , 250 , 251 , 252 , 253 , 254 , 256 , 257 , 258 , 259 , 260 , 261 , 263 , 264 , 265 , 267 , 268 , 269 , 270 , 271 , 272 , 273 , 276 , 277 , 278 , 279 , 280 , 281 , 286 , 290 , 291 , 292 , 293 , 294 , 295 , 296 , 297 , 298 , 303 , 304 , 317 , 318 , 319 , 320 , 321 , 322 , 323 , 324 , 326 , 329 , 333 , 334 , 335 , 336 , 337 , 338 , 344 , 350 , 351 , 354 , 355 , 361 , 363 , 364 , 376 , 382 , 383 , 384 , 385 , 386 , 391 , 392 , 393 , 394 , 401 , 402 , 403 , 405 , 406 , 407 , 410 , 411 , 412 , 415 , 416 , 417 , 418 , 425 , 426 , 427 , 429 , 430 , 431 , 432 , 433 , 434 , 435 , 443 , 459 , 466 , 467 ) , mass spectrometry (in vitro) ( 138 ) , microscopy-colocalization with upstream kinase ( 494 ) , mutation of modification site ( 17 , 19 , 23 , 211 , 213 , 274 , 283 , 369 , 372 , 420 , 423 , 424 , 439 , 458 , 469 ) , peptide sequencing ( 387 ) , phospho-antibody ( 10 , 12 , 14 , 17 , 19 , 20 , 21 , 22 , 23 , 24 , 25 , 26 , 27 , 30 , 32 , 33 , 34 , 35 , 36 , 37 , 38 , 40 , 41 , 42 , 43 , 44 , 46 , 47 , 48 , 49 , 51 , 52 , 53 , 58 , 59 , 61 , 62 , 63 , 64 , 66 , 70 , 73 , 74 , 75 , 77 , 78 , 86 , 87 , 88 , 89 , 90 , 92 , 94 , 95 , 98 , 99 , 103 , 104 , 105 , 106 , 107 , 108 , 109 , 110 , 112 , 113 , 114 , 115 , 116 , 117 , 118 , 119 , 120 , 122 , 123 , 124 , 125 , 126 , 127 , 128 , 129 , 130 , 131 , 132 , 137 , 140 , 141 , 142 , 143 , 144 , 150 , 151 , 152 , 153 , 154 , 155 , 158 , 159 , 174 , 175 , 179 , 187 , 188 , 189 , 190 , 198 , 199 , 200 , 201 , 202 , 203 , 204 , 210 , 211 , 212 , 213 , 214 , 215 , 221 , 222 , 223 , 225 , 255 , 266 , 274 , 275 , 282 , 283 , 284 , 287 , 288 , 289 , 300 , 302 , 305 , 306 , 307 , 308 , 309 , 310 , 311 , 312 , 313 , 314 , 316 , 325 , 327 , 328 , 330 , 331 , 332 , 339 , 340 , 341 , 342 , 343 , 345 , 346 , 347 , 348 , 349 , 352 , 353 , 356 , 357 , 358 , 359 , 360 , 362 , 365 , 366 , 367 , 368 , 369 , 370 , 371 , 372 , 373 , 374 , 375 , 377 , 378 , 379 , 380 , 381 , 389 , 397 , 398 , 400 , 404 , 408 , 409 , 413 , 414 , 419 , 420 , 421 , 422 , 423 , 424 , 428 , 436 , 437 , 438 , 440 , 441 , 442 , 444 , 445 , 446 , 447 , 448 , 449 , 450 , 451 , 452 , 453 , 454 , 455 , 456 , 458 , 459 , 460 , 461 , 462 , 463 , 464 , 465 , 469 , 470 , 471 , 472 , 473 , 474 , 475 , 476 , 477 , 478 , 479 , 480 , 481 , 482 , 483 , 484 , 486 , 487 , 488 , 489 , 490 , 491 , 492 , 493 , 494 , 495 , 496 , 497 , 498 , 499 , 500 , 501 , 502 , 503 , 504 , 505 , 506 , 507 , 508 , 509 , 510 , 511 , 512 , 513 , 514 , 515 , 516 , 518 , 519 , 520 , 521 , 522 ) , phosphopeptide mapping ( 513 ) , western blotting ( 10 , 12 , 14 , 17 , 19 , 20 , 21 , 22 , 23 , 24 , 25 , 26 , 27 , 30 , 32 , 33 , 34 , 35 , 36 , 37 , 38 , 40 , 41 , 42 , 43 , 44 , 46 , 47 , 48 , 49 , 51 , 52 , 53 , 58 , 59 , 61 , 62 , 63 , 64 , 66 , 70 , 73 , 74 , 75 , 77 , 78 , 86 , 87 , 88 , 89 , 90 , 92 , 94 , 95 , 98 , 99 , 103 , 104 , 105 , 106 , 107 , 108 , 109 , 110 , 112 , 113 , 114 , 115 , 116 , 117 , 118 , 119 , 120 , 122 , 123 , 124 , 125 , 126 , 128 , 129 , 130 , 131 , 132 , 137 , 140 , 141 , 142 , 143 , 144 , 150 , 151 , 152 , 153 , 154 , 155 , 158 , 159 , 174 , 175 , 179 , 187 , 188 , 189 , 190 , 198 , 199 , 200 , 201 , 202 , 203 , 204 , 210 , 211 , 212 , 213 , 214 , 215 , 221 , 222 , 223 , 225 , 255 , 266 , 274 , 275 , 282 , 283 , 284 , 287 , 289 , 300 , 302 , 305 , 306 , 307 , 309 , 310 , 311 , 312 , 313 , 314 , 316 , 325 , 327 , 328 , 330 , 331 , 332 , 339 , 340 , 342 , 345 , 346 , 347 , 348 , 349 , 352 , 353 , 356 , 357 , 358 , 359 , 360 , 362 , 365 , 366 , 367 , 368 , 369 , 370 , 371 , 372 , 373 , 374 , 377 , 378 , 379 , 380 , 387 , 389 , 397 , 400 , 408 , 413 , 423 , 437 , 438 , 440 , 441 , 442 , 444 , 445 , 446 , 448 , 449 , 450 , 451 , 453 , 454 , 455 , 456 , 458 , 460 , 461 , 462 , 464 , 469 , 470 , 473 , 474 , 475 , 476 , 477 , 478 , 479 , 482 , 483 , 484 , 486 , 487 , 489 , 490 , 491 , 493 , 498 , 501 , 502 , 505 , 506 , 510 , 511 , 512 , 513 , 514 , 515 , 518 , 519 , 520 , 521 , 522 )
Disease tissue studied:
adrenal cancer ( 482 ) , pheochromocytoma ( 482 ) , breast cancer ( 70 , 357 , 387 , 512 ) , cervical cancer ( 487 ) , cervical adenocarcinoma ( 487 ) , colorectal cancer ( 451 ) , colorectal carcinoma ( 451 ) , leukemia ( 182 , 183 , 184 , 185 , 275 , 291 , 292 , 293 , 294 , 295 , 296 , 297 , 298 ) , acute erythroid leukemias, including erythroleukemia (M6a) and very rare pure erythroid leukemia (M6b) ( 275 ) , chronic myelogenous leukemia ( 291 , 292 , 293 , 294 , 295 , 296 , 297 , 298 ) , liver cancer ( 124 , 372 ) , lung cancer ( 114 , 263 , 264 , 265 , 267 , 268 , 269 , 276 , 277 , 278 , 279 , 280 , 281 , 332 , 360 ) , non-small cell lung cancer ( 114 , 133 , 263 , 264 , 265 , 276 , 277 , 278 , 279 , 280 , 281 ) , lymphoma ( 492 ) , B cell lymphoma ( 492 ) , neuroblastoma ( 106 , 449 , 486 ) , pancreatic cancer ( 152 , 284 ) , pancreatic carcinoma ( 152 , 284 ) , prostate cancer ( 74 ) , melanoma skin cancer ( 73 , 89 , 205 , 211 ) , testicular cancer ( 146 , 148 , 454 ) , diabetes mellitus ( 212 , 372 ) , type 2 diabetes ( 212 , 372 ) , Huntington's disease ( 47 ) , Turner-like syndrome ( 208 , 209 )
Relevant cell line - cell type - tissue:
'3T3-L1, differentiated' (adipocyte) ( 28 , 42 , 56 , 88 ) , 'B lymphocyte, precursor' ( 274 ) , 'brain, cerebellum' ( 413 , 511 ) , 'brain, cerebral cortex' ( 17 , 358 , 447 , 507 ) , 'brain, cerebrum' ( 413 , 511 ) , 'brain, embryonic' ( 271 , 333 , 335 ) , 'brain, embryonic' [BAG1 (mouse)] ( 399 ) , 'brain, hippocampus' ( 49 , 150 , 201 , 340 , 373 , 465 ) , 'brain, hippocampus' [DLG3 (mouse), homozygous knockout] ( 339 ) , 'brain, hypothalamus, suprachiasmatic nucleus' ( 422 ) , 'brain, striatum' ( 47 , 345 , 409 , 440 , 448 , 456 ) , 'epithelial, lung' [homozygous knockout] ( 123 ) , 'fat, brown' ( 121 ) , 'liver, fetal' ( 371 ) , 'muscle, skeletal' ( 187 , 266 , 327 , 455 ) , 'neuron, cortical'-brain ( 48 , 64 , 143 , 483 , 488 , 497 ) , 'neuron, cortical'-brain [NYAP2 (mouse), homozygous knockout] ( 78 ) , 'neuron, dorsal horn'-spinal cord ( 288 ) , 'neuron, hippocampal'-brain [neurogranin (mouse)] ( 501 ) , 'neuron, superior cervical ganglion' ( 222 ) , 'renal, podocyte' ( 131 ) , 'stem, embryonic' ( 156 , 157 , 160 , 161 , 162 , 163 , 164 , 165 , 166 , 167 , 266 ) , 'stem, mesenchymal' ( 303 , 304 ) , 293 (epithelial) [DOR-1 (mouse)] ( 516 ) , 293 (epithelial) ( 43 , 203 , 389 , 423 , 424 , 513 ) , 32D (myeloid) ( 110 , 478 , 519 ) , 3T3 (fibroblast) [CDC42 (human), transfection] ( 54 ) , 3T3 (fibroblast) [INSR (human)] ( 513 ) , 3T3 (fibroblast) [INSR (mouse), transfection] ( 200 ) , 3T3 (fibroblast) [KRas (human), transfection] ( 54 ) , 3T3 (fibroblast) [Pyk2 (human), transfection, stable Pyk2 (v5-His tagged) transfection, in RU-486 (mifepristone)-inducible expression system] ( 139 ) , 3T3 (fibroblast) [SHP-2 (mouse), homozygous knockout] ( 381 , 398 , 421 , 423 , 439 , 442 , 464 , 476 , 481 , 500 , 522 ) , 3T3 (fibroblast) [Src (human)] ( 360 ) , 3T3 (fibroblast) ( 14 , 54 , 115 , 188 , 200 , 302 , 365 , 369 , 387 , 408 , 431 , 432 , 433 , 434 , 435 , 450 , 466 , 467 , 469 , 487 , 490 , 506 , 520 , 521 ) , 3T3-L1 (fibroblast) ( 63 , 94 , 151 , 312 , 314 , 325 , 376 , 470 ) , 4T1 (breast cell) ( 512 ) , AB.1 (T lymphocyte) ( 128 ) , adipocyte-adipose tissue ( 510 ) , adipose tissue ( 266 ) , adipose tissue [DUSP6 (mouse), homozygous knockout] ( 44 ) , alphaT3-1 (pituitary cell) ( 51 ) , aorta ( 342 ) , artery ( 282 ) , B lymphocyte ( 82 , 274 ) , B lymphocyte-spleen ( 112 , 142 , 348 ) , B lymphocyte-spleen [PTEN (mouse), transgenic] ( 159 ) , B16 (melanocyte) ( 73 ) , B16F1 (melanocyte) ( 89 , 211 ) , B16F10 ( 21 ) , BAC1.2F5 (macrophage) ( 503 ) , BaF3 ('B lymphocyte, precursor') [EGFR (human)] ( 360 ) , BaF3 ('B lymphocyte, precursor') [FLT3 (human)] ( 374 ) , BaF3 ('B lymphocyte, precursor') ( 58 , 140 , 153 , 181 , 200 , 210 , 275 , 291 , 292 , 293 , 294 , 295 , 296 , 297 , 298 , 313 , 353 , 382 , 383 , 384 , 385 , 386 , 391 , 392 , 393 , 394 , 400 , 401 , 402 , 403 , 404 , 405 , 406 , 407 , 410 , 411 , 412 , 415 , 416 , 417 , 418 , 425 , 426 , 427 , 443 , 478 , 491 ) , BALB/MK (keratinocyte) ( 518 ) , beta-pancreas ( 152 ) , beta-pancreas [INSR (mouse), transgenic] ( 132 ) , bladder ( 287 ) , BMMC (mast) ( 46 , 119 , 514 ) , bone marrow ( 20 , 353 ) , brain ( 10 , 68 , 71 , 72 , 121 , 136 , 180 , 270 , 286 , 334 , 336 , 494 ) , brain [DARPP-32 (mouse), homozygous knockout] ( 444 ) , brain [NYAP2 (mouse), homozygous knockout] ( 78 ) , breast cell ( 70 ) , C2C12 (myoblast) ( 22 , 226 , 227 , 228 , 229 , 230 , 231 , 232 , 233 , 437 , 458 , 473 ) , C2C12-D (muscle cell) ( 337 , 338 ) , C3H10T1/2 (fibroblast) ( 249 , 250 , 251 , 252 , 352 , 471 ) , CCE ( 446 ) , CD4+ (T lymphocyte) ( 102 ) , CHO (fibroblast) ( 19 ) , CMT-93 (intestinal) ( 451 ) , colon ( 126 ) , COS (fibroblast) ( 27 , 58 , 200 , 367 , 450 , 469 , 489 ) , CTL-EN (T lymphocyte) ( 289 ) , dendritic cell ( 12 , 302 ) , dendritic cell [MAPKAPK2 (mouse), homozygous knockout] ( 302 ) , dendritic cell [MSK1 (mouse), homozygous knockout] ( 302 ) , E14 ('neuron, hippocampal') ( 66 ) , E14tg2a ('stem, embryonic') ( 24 , 446 ) , embryo ( 72 , 371 ) , embryonic ( 59 ) , endothelial ( 215 ) , endothelial-pulmonary artery ( 137 ) , endothelial-vein ( 137 ) , epithelial ( 463 ) , epithelial-'kidney, tubule' ( 307 ) , epithelial-lens ( 328 ) , erythroblast ( 275 ) , ES (stem) ( 43 , 378 , 380 ) , F9 (testicular) ( 146 , 454 ) , Fao (hepatic) ( 124 , 372 ) , fibroblast-embryo [BAG1 (mouse)] ( 399 ) , GD25 (fibroblast) ( 475 ) , GL261 (glial) ( 154 ) , GT1-7 (neuron) ( 305 , 375 , 480 ) , HaCaT (keratinocyte) ( 306 ) , heart ( 57 , 121 , 203 , 206 , 207 , 208 , 209 , 235 , 266 , 272 , 309 , 326 , 329 , 356 ) , HEK293T (epithelial) ( 19 , 64 , 77 , 90 ) , HEL (erythroid) ( 275 ) , HeLa (cervical) ( 109 , 439 ) , HeLa S3 (cervical) ( 487 ) , hepatocyte ( 380 ) , HepG2 (hepatic) ( 372 ) , HT-22 (neuron) ( 488 ) , HT-4 (neuron) ( 488 ) , HUVEC (endothelial) ( 108 , 215 ) , IBE (endothelial) ( 493 ) , J774 (macrophage) ( 477 , 498 ) , JB (epithelial) ( 441 , 508 ) , JB6 RT101 (epidermal) ( 379 ) , Jurkat (T lymphocyte) ( 213 ) , keratinocyte ( 86 ) , keratinocyte-skin [IGF1 (mouse)] ( 389 ) , kidney ( 121 ) , liver ( 15 , 55 , 65 , 72 , 121 , 124 , 199 , 266 , 273 , 321 , 322 , 323 , 324 , 344 , 372 , 504 ) , liver [Akt2 (mouse), homozygous knockout] ( 317 , 318 , 319 , 320 ) , LLC-PK1 (renal) ( 462 ) , lung ( 121 , 133 , 215 , 224 , 263 , 264 , 265 , 332 , 350 , 351 ) , lung [EGFR (mouse), transgenic, mutant] ( 268 ) , lung [EGFR (mouse), transgenic] ( 267 ) , lung [HRas (mouse), transgenic] ( 269 ) , lung [p27Kip1 (mouse), genetic knockin] ( 95 ) , macrophage ( 367 ) , macrophage-blood ( 424 ) , macrophage-bone marrow ( 30 , 62 , 134 , 341 , 347 , 414 ) , macrophage-bone marrow [Cot (mouse)] ( 300 ) , macrophage-bone marrow [DUSP1 (mouse), homozygous knockout] ( 134 ) , macrophage-bone marrow [NFkB-p105 (human)] ( 300 ) , macrophage-peritoneum ( 23 , 105 , 515 ) , mast-bone marrow ( 26 , 129 , 202 , 290 , 348 , 368 , 484 ) , mast-bone marrow [PTPRA (mouse), homozygous knockout] ( 214 ) , mast-bone marrow [SHP-2 (mouse), homozygous knockout] ( 174 ) , MC/9 (mast) ( 478 ) , MCF-7 (breast cell) ( 387 ) , MCP-5 (mast) ( 290 ) , MCT cells (epithelial) ( 212 ) , MDPC-23 (dental pulp cells) ( 61 ) , MEDF [HRas (mouse), HRas V12, HDAC6 -/+] ( 191 , 192 ) , MEF (fibroblast) [HRas (mouse), HRas V12] ( 194 , 195 ) , MEF (fibroblast) [IGF1R (mouse)] ( 343 , 419 , 436 , 452 ) , MEF (fibroblast) [LKB1 (mouse)] ( 461 ) , MEF (fibroblast) [MSK1 (mouse), homozygous knockout, msk2] ( 505 ) , MEF (fibroblast) [p53 (mouse), homozygous knockout] ( 96 ) , MEF (fibroblast) [PDGFRA (mouse), genetic knockin] ( 198 ) , MEF (fibroblast) [PKR (mouse), homozygous knockout] ( 117 ) , MEF (fibroblast) [PTP1B (mouse), homozygous knockout] ( 220 ) , MEF (fibroblast) [RAF1 (mouse), homozygous knockout] ( 221 ) , MEF (fibroblast) [Raptor (mouse), knockdown] ( 60 ) , MEF (fibroblast) [RICTOR (mouse), knockdown] ( 60 ) , MEF (fibroblast) [TSC2 (mouse), homozygous knockout] ( 97 ) , MEF (fibroblast) ( 23 , 53 , 60 , 75 , 77 , 89 , 90 , 97 , 109 , 112 , 122 , 179 , 193 , 196 , 220 , 234 , 255 , 283 , 306 , 310 , 316 , 330 , 354 , 355 , 356 , 362 , 363 , 364 , 367 , 369 , 370 , 445 , 474 , 508 , 509 ) , Mel-Ab (melanocyte) ( 113 ) , mesangial ( 472 ) , Met-1 (breast cell) ( 70 ) , microglia ( 346 ) , microvessel endothelial-lung [GIT1 (mouse), homozygous knockout] ( 52 ) , mIMCD-3 (epithelial) ( 502 ) , MIN6 (pancreatic) ( 152 , 284 ) , MLE (epithelial) ( 420 ) , mLEC (epithelial) ( 104 ) , MLO-Y4 (osteoblast) ( 25 ) , MLP-29 ( 175 ) , MMTV-PyMT (breast cell) [JNK2 (mouse), homozygous knockout] ( 107 ) , mpkCCD (renal) ( 145 ) , MS1 (endothelial) ( 437 ) , muscle ( 458 ) , myeloid ( 347 ) , myeloid-bone marrow ( 275 ) , myocyte-heart ( 41 , 203 , 311 , 356 , 397 ) , N18 (neuron) ( 486 ) , Neuro-2a (neuron) ( 106 ) , neuron-'brain, cerebral cortex' ( 103 ) , neuron:postsynaptic density-'brain, hippocampus, CA1 region' ( 18 ) , NHDF (fibroblast) ( 53 ) , NMuMG (epithelial) ( 512 ) , NSCLC (pulmonary) ( 114 ) , osteoclast ( 347 ) , P19 (testicular) ( 148 ) , pancreas ( 121 ) , PC-12 (chromaffin) ( 428 , 482 ) , platelet-blood ( 127 ) , preosteoclast ( 377 ) , prostate ( 74 ) , PYS-2 (epithelial) ( 149 ) , R1 ('stem, embryonic') ( 486 ) , R22 ('muscle, smooth') ( 283 ) , RAW 264 (macrophage) ( 424 , 438 , 453 ) , RAW 264.7 (macrophage) ( 39 , 116 , 182 , 183 , 184 , 185 , 190 ) , REF52 (fibroblast) ( 489 ) , skin ( 120 , 471 ) , skin [Fyn (mouse), transgenic] ( 155 ) , skin [mGluR1 (mouse), transgenic, TG mutant mice] ( 205 ) , SN56 (neuron) ( 449 ) , Sor577 ( 429 ) , SorA ( 430 ) , spleen ( 121 , 169 , 173 , 178 ) , STC-1 (endocrine) ( 496 ) , stromal ( 99 ) , Swiss 3T3 (fibroblast) ( 460 ) , SYF (fibroblast) [Src iso1 (mouse), transfection] ( 69 ) , SYF (fibroblast) ( 130 , 283 , 369 ) , T lymphocyte ( 223 ) , T lymphocyte [FOXO1A (mouse), transgenic] ( 98 ) , T lymphocyte [PELI1 (mouse), homozygous knockout] ( 87 ) , T lymphocyte-blood ( 102 , 204 , 308 ) , T lymphocyte-lymph node ( 135 , 158 , 331 , 348 ) , T lymphocyte-lymph node [PRKD1 (mouse), genetic knockin] ( 125 ) , T lymphocyte-lymph node [PRKD2 (mouse), genetic knockin] ( 125 ) , T lymphocyte-spleen ( 118 , 359 ) , T lymphocyte-spleen [LAT (mouse), transgenic] ( 144 ) , T lymphocyte-thymus ( 102 ) , T47D (breast cell) ( 357 ) , testis ( 121 , 168 , 171 , 177 ) , thymocyte ( 366 ) , thymocyte [CBL (mouse), homozygous knockout] ( 141 ) , thymus ( 170 , 172 , 176 ) , thyroid [BRAF (human), genetic knockin] ( 92 ) , uterus ( 32 ) , vascular smooth muscle cell ('muscle, smooth') ( 225 , 283 ) , VSMC-aorta ( 479 ) , WEHI-231 (B lymphocyte) ( 492 )

Upstream Regulation
Regulatory protein:
ADRB1 (mouse) ( 57 ) , AIF1 (mouse) ( 34 ) , Akt1 (mouse) ( 514 ) , ALK (human) ( 140 ) , ARAF (human) ( 284 ) , ARAF (mouse) ( 284 ) , ARHGEF7 (mouse) ( 369 ) , ARRB1 (mouse) ( 152 ) , BAG1 (mouse) ( 399 ) , Bcl-10 (mouse) ( 348 ) , BCR-ABL1 (human) ( 360 ) , BRAF (human) ( 222 ) , BRAF iso1 (mouse) ( 452 ) , CAMK2D (human) ( 305 ) , CARD11 (mouse) ( 348 ) , CARD9 (mouse) ( 35 ) , CBL (mouse) ( 366 ) , Cbl-b (mouse) ( 366 ) , CD151 (mouse) ( 26 ) , CD44 (mouse) ( 367 ) , CD74 (mouse) ( 367 ) , CDC42 iso1 (mouse) ( 369 ) , CDK5R1 (mouse) ( 440 ) , Cot (human) ( 90 ) , Cot (mouse) ( 419 ) , dectin-1 (mouse) ( 35 ) , DLG3 (mouse) ( 339 ) , DOK3 (mouse) ( 62 ) , DUSP6 (mouse) ( 44 , 124 ) , EAR-2 (mouse) ( 223 ) , EGFR (mouse) ( 283 ) , eNOS (mouse) ( 311 ) , ERG (mouse) ( 74 ) , ERK2 (mouse) ( 379 ) , FADD (mouse) ( 40 ) , FAK iso2 (mouse) ( 445 , 469 ) , FCER1A (mouse) ( 290 ) , Fes (mouse) ( 202 , 503 ) , FGFR1 (human) ( 313 ) , FGFR2 (human) ( 439 ) , FLT3 (human) ( 404 ) , FMR1 (mouse) ( 17 , 373 ) , FOXO1A (mouse) ( 124 ) , FOXP1 (mouse) ( 98 ) , G-alpha i2 (human) ( 90 ) , G-beta 1 (mouse) ( 90 ) , GAB2 (mouse) ( 20 ) , GIPC1 (mouse) ( 137 ) , GIT1 (human) ( 52 ) , GLRX1 (mouse) ( 328 ) , GRB10 (human) ( 58 ) , GRB10 (mouse) ( 31 ) , HePTP (mouse) ( 204 ) , HRas (mouse) ( 75 , 114 , 513 ) , ICMT (mouse) ( 474 ) , IGF1R (mouse) ( 457 ) , IL17RD (mouse) ( 476 ) , IRS1 (mouse) ( 510 ) , ITGA9 (human) ( 353 ) , JAK2 (human) ( 275 , 491 ) , JNK2 (mouse) ( 30 , 75 , 107 ) , KRas (mouse) ( 54 , 74 , 362 , 518 ) , KSR (human) ( 122 ) , LAB (mouse) ( 359 ) , LAT (mouse) ( 144 ) , MAPKAPK2 (mouse) ( 302 ) , MAPKAPK3 (mouse) ( 302 ) , MEK1 (mouse) ( 104 , 489 ) , MEKK1 (mouse) ( 43 ) , mGluR5 (mouse) ( 288 ) , MRas (human) ( 478 ) , MSK1 (human) ( 505 ) , MSK1 (mouse) ( 505 ) , MSK2 (mouse) ( 505 ) , neurogranin (mouse) ( 501 ) , NPC1 (mouse) ( 413 , 511 ) , NPM1 (human) ( 140 ) , NYAP2 (mouse) ( 78 ) , PAG (rat) ( 255 ) , PAK1 (human) ( 489 ) , PDGFRA (mouse) ( 198 ) , PDK1 (mouse) ( 266 , 380 ) , PELI1 (mouse) ( 87 ) , PHLPP (mouse) ( 102 ) , PKCA (mouse) ( 215 ) , PKCT (mouse) ( 282 ) , PPP1CC (human) ( 225 ) , PRKD1 (mouse) ( 460 ) , PRMT5 (human) ( 89 ) , PRMT5 (mouse) ( 89 ) , PRMT5 (rat) ( 89 ) , PTEN (mouse) ( 36 ) , PTP1B (mouse) ( 137 ) , PTPRB (mouse) ( 137 ) , PTPRJ (mouse) ( 137 ) , PTPRM (mouse) ( 137 ) , RAB11A (mouse) ( 137 ) , Rab7 (mouse) ( 137 ) , RAC1 (mouse) ( 489 ) , RAF1 (human) ( 89 ) , RAF1 (mouse) ( 489 ) , RAIG1 (mouse) ( 123 ) , Ret (human) ( 222 , 365 ) , RHOC (mouse) ( 73 ) , ROCK1 (mouse) ( 187 ) , RSK2 (mouse) ( 306 ) , SGPL1 (mouse) ( 90 ) , SH3BP2 (mouse) ( 347 ) , SHC1 iso2 (human) ( 343 ) , SHP-2 (mouse) ( 174 , 500 ) , SOCS1 (mouse) ( 469 ) , SOCS3 (mouse) ( 469 ) , Src (human) ( 360 ) , Src iso1 (mouse) ( 69 , 73 ) , Syk (mouse) ( 274 ) , syndecan-4 (mouse) ( 215 ) , TAK1 (mouse) ( 356 ) , TBK1 (mouse) ( 362 ) , Tel (human) ( 491 ) , TSC2 (mouse) ( 132 , 370 ) , UCP2 (mouse) ( 341 ) , VEGFR3 (mouse) ( 104 ) , Vinculin (mouse) ( 454 ) , ZAP70 (mouse) ( 274 )
Putative in vivo kinases:
MEK1 (mouse) ( 387 )
Kinases, in vitro:
MEK1 (mouse) ( 489 ) , MEK1 (rat) ( 138 )
Putative upstream phosphatases:
PPP2CA (mouse) ( 503 ) , STS-1 (mouse) ( 127 )
Phosphatases, in vitro:
STS-1 (mouse) ( 127 )
Treatments:
15d-PGJ2 ( 451 ) , 17-beta-estradiol ( 32 ) , 1Na-PP1 ( 143 ) , 22-hydroxycholesterol ( 420 ) , 5'-methylthioadenosine ( 89 ) , 8-(3-chlorostyryl) caffeine ( 309 ) , 9d ( 201 ) , A23187 ( 515 ) , acadesine ( 461 ) , adriamycin ( 117 ) , AG1296 ( 404 ) , AG1478 ( 86 , 131 , 186 , 428 , 480 ) , AG490 ( 43 , 477 ) , AGEs ( 23 ) , Akt-I-1 ( 284 ) , Akt_activator_compound_11 ( 115 ) , Akt_inhibitor_VIII ( 200 ) , alloxazine ( 309 ) , alpha-lipoic_acid ( 106 ) , amino_acid_starvation ( 200 ) , amino_acids ( 77 , 200 ) , amphoterin ( 486 ) , angiopoietin-1 ( 437 ) , angiopoietin-2 ( 437 ) , anisomycin ( 302 , 505 , 515 ) , anti-CD3 ( 128 , 141 , 213 , 308 , 331 , 366 , 388 ) , anti-CD3/CD28 ( 98 , 118 , 141 , 359 ) , anti-CD4 ( 141 , 366 ) , anti-CD8 ( 366 ) , anti-CTLA-4 ( 158 ) , anti-Fas ( 221 ) , anti-IgB ( 274 ) , anti-IgE ( 174 ) , anti-IgM ( 142 , 159 ) , anti-ITGA4 ( 437 ) , anti-ITGA6 ( 437 ) , anti-ITGB3 ( 437 ) , antichymotrypsin ( 358 ) , antigenic stimulation ( 129 ) , antitrypsin ( 358 ) , aphidicolin ( 450 ) , apigenin ( 477 ) , apomorphine ( 409 ) , atorvastatin ( 309 ) , AZD8055 ( 53 ) , bacterial infection ( 12 , 126 ) , BAPTA-AM ( 480 , 493 , 496 , 506 ) , Bay61-3606 ( 129 ) , BDNF ( 64 , 143 , 521 ) , benzo(a)pyrene ( 332 ) , beta-amyloid_40 ( 449 ) , BFD-22 ( 21 ) , BI-D1870 ( 23 , 158 , 302 ) , bicuculline ( 103 ) , BIRA766 ( 129 ) , BIRB-0796 ( 302 ) , bisindolylmaleimide ( 486 ) , black_tea_polyphenols ( 120 ) , bombesin ( 186 , 460 ) , bradykinin ( 33 ) , BRL37344 ( 442 ) , caffeine ( 345 ) , calphostin_C ( 486 ) , calyculin_A ( 518 ) , cAMP_analog ( 481 , 493 ) , cell_adhesion ( 204 ) , cell_detachment ( 454 ) , CGP77675 ( 462 ) , CGS_21680 ( 345 ) , chelerythrine ( 486 ) , ciclopirox_olamine ( 104 ) , cocaine ( 440 , 444 ) , cold_water_stress ( 340 ) , colforsin ( 122 , 345 , 423 , 436 , 493 , 501 ) , compound_56 ( 186 ) , ConA ( 199 ) , convulxin ( 127 ) , curcumin ( 116 ) , curdlan ( 35 ) , CXCL12 ( 301 , 492 ) , cyclic_stretch ( 131 ) , cycloheximide ( 189 ) , cytochalasin_D ( 462 ) , dactolisib ( 70 ) , DDA ( 204 ) , depolarization ( 448 ) , desmopressin ( 145 ) , DETA-NONOate ( 311 ) , dexamethasone ( 312 , 352 ) , DHPG ( 288 , 373 ) , differentiation ( 61 , 114 ) , DMNQ ( 225 ) , DNP ( 514 ) , DPCPX ( 309 ) , DPDPE ( 516 ) , DPGlu ( 480 ) , dronabinol ( 48 ) , DTLET ( 516 ) , EDTA ( 437 ) , EGF ( 33 , 43 , 86 , 89 , 107 , 122 , 123 , 188 , 220 , 306 , 307 , 330 , 349 , 352 , 369 , 423 , 428 , 442 , 450 , 452 , 460 , 474 , 476 , 480 , 489 , 499 , 500 , 502 , 505 , 509 , 512 , 513 , 518 , 522 ) , EGTA ( 189 , 480 ) , Epo ( 153 , 275 , 396 ) , epoxomicin ( 175 ) , estradiol ( 449 , 507 ) , ethanol ( 494 , 504 ) , ether ( 340 ) , etoposide ( 53 ) , faslodex ( 357 , 449 ) , fedratinib ( 275 ) , FGF1 ( 14 , 89 , 488 ) , FGF2 ( 89 , 215 , 476 , 480 , 482 , 493 ) , fibronectin ( 423 , 489 ) , fingolimod ( 47 ) , fisetin ( 49 ) , FL ( 374 , 404 ) , fluid_shear_stress ( 25 ) , food deprivation ( 340 ) , G-CSF ( 353 ) , GDNF ( 222 ) , gefitinib ( 360 ) , gelatin ( 486 ) , GF109203X ( 90 , 186 , 493 ) , GH ( 381 ) , GLP-1 ( 152 ) , glucose ( 131 , 132 , 212 , 468 , 472 ) , GM-CSF ( 289 ) , GnRH ( 51 , 305 , 480 ) , Go_6976 ( 486 ) , Go_6983 ( 480 ) , guanosine ( 346 ) , GW4869 ( 42 ) , H-89 ( 122 , 152 , 204 , 357 , 423 , 486 ) , H2O2 ( 128 , 131 , 343 , 408 , 428 ) , heparin sodium ( 377 ) , herstatin ( 499 ) , HGF ( 89 ) , honokiol ( 94 ) , hydroxyurea ( 387 ) , hypertonic_buffer ( 398 ) , hypoxia ( 151 , 497 ) , IBMX ( 122 , 312 , 352 , 423 , 436 ) , IFN-alpha ( 179 ) , IFN-gamma ( 346 , 477 ) , IgE ( 514 ) , IGF-1 ( 41 , 390 , 442 , 457 , 468 , 518 , 519 ) , IGF-2 ( 390 ) , IgG ( 414 ) , IL-18 ( 27 ) , IL-1b ( 419 ) , IL-3 ( 140 , 275 , 400 , 404 , 478 , 491 , 519 ) , IL-33 ( 39 ) , IL-4 ( 478 ) , IL-6 ( 342 ) , IL-9 ( 478 ) , imatinib ( 140 ) , insulin ( 22 , 56 , 77 , 88 , 94 , 124 , 132 , 187 , 200 , 212 , 248 , 266 , 282 , 312 , 314 , 375 , 376 , 390 , 421 , 442 , 455 , 459 , 470 , 506 , 510 , 513 ) , ionizing_radiation ( 53 ) , ionomycin ( 87 , 128 , 348 , 518 ) , ischemia/reperfusion ( 10 , 311 , 395 ) , isoproterenol ( 442 , 481 ) , iturelix ( 305 ) , JNK_inhibitor_I ( 342 ) , kaempferol ( 306 ) , kainic_acid ( 465 ) , KGF ( 439 ) , KN-93 ( 305 ) , KT5823 ( 103 ) , L-744,832 ( 518 ) , L-NAME ( 103 ) , laminin-1 ( 486 ) , leptin ( 498 ) , leucine ( 89 ) , levamfetamine ( 444 ) , LG268 ( 455 ) , licochalcone_A ( 190 ) , licochalcone_B ( 190 ) , licochalcone_C ( 190 ) , licochalcone_D ( 190 ) , LIF ( 378 , 446 ) , LIF withdrawal ( 24 ) , light ( 29 , 422 ) , lonafarnib ( 40 ) , long-term_potentiation ( 150 ) , low_glucose ( 131 ) , LPA ( 86 , 100 , 442 , 452 , 509 ) , LPS ( 30 , 62 , 105 , 116 , 134 , 190 , 302 , 341 , 414 , 424 , 438 , 451 , 504 ) , LY294002 ( 22 , 158 , 200 , 213 , 371 , 396 , 446 , 488 , 493 , 513 ) , M-CSF ( 315 , 347 , 490 , 503 ) , methotrexate ( 474 ) , methyl-beta-cyclodextrin ( 352 ) , MG132 ( 175 , 438 ) , midazolam ( 397 ) , MIF ( 367 ) , miR-181a ( 331 ) , MK801 ( 103 ) , MMS ( 370 ) , MnTBAP ( 103 ) , morphine ( 516 ) , MPTP ( 456 ) , MRS-1523 ( 309 ) , MSH ( 89 ) , muramyl_dipeptide ( 99 ) , NAC ( 106 ) , neuregulin ( 458 ) , nicotine ( 473 ) , nifedipine ( 152 ) , NMDA ( 339 ) , nocodazole ( 450 ) , nomifensine ( 456 ) , NP68 ( 158 ) , NSC697923 ( 43 ) , NTCU ( 332 ) , NVP-BKM120 ( 70 ) , ODQ ( 103 ) , OH-BBN ( 287 ) , okadaic_acid ( 360 , 515 ) , orantinib ( 365 ) , OVA ( 125 ) , PACAP ( 422 ) , palmitate ( 282 , 310 ) , Pam3CSK4 ( 302 ) , PAR1-activating_peptide ( 484 ) , PD0325901 ( 40 ) , PD169316 ( 508 ) , PD184352 ( 32 , 302 , 505 ) , PD90059 ( 357 ) , PD98059 ( 22 , 23 , 51 , 88 , 106 , 126 , 215 , 284 , 342 , 400 , 420 , 442 , 449 , 451 , 477 , 479 , 482 , 485 , 487 , 488 , 493 , 495 , 498 , 508 , 513 , 518 , 519 ) , PDGF ( 198 , 325 , 328 , 464 , 476 , 479 , 509 ) , peptidoglycan ( 453 ) , peptones ( 496 ) , PGE2 ( 25 , 299 ) , phorbol_ester ( 87 , 89 , 120 , 189 , 302 , 348 , 381 , 452 , 462 , 480 , 493 , 501 , 505 , 509 , 515 , 518 ) , pilocarpine ( 465 ) , PKC-theta_pseudosubstrate ( 282 ) , pomegranate_wine ( 332 ) , PP1 ( 51 , 464 , 513 ) , PP2 ( 213 , 352 , 367 , 457 , 464 , 480 , 493 , 507 ) , progestin_R5020 ( 357 ) , PTX ( 90 , 480 ) , quinpirole ( 483 ) , racepinefrine ( 327 , 481 ) , Raf1_kinase_inhibitor_I ( 284 ) , RANKL ( 347 ) , rapamycin ( 32 , 37 , 41 , 132 , 158 , 200 , 380 , 485 , 518 ) , restraint stress ( 67 ) , resveratrol ( 120 ) , retinoic_acid ( 420 , 486 ) , RGD ( 437 ) , RGE ( 437 ) , Ro31-8220 ( 480 ) , rosiglitazone ( 94 , 455 ) , rottlerin ( 343 ) , S107 ( 67 ) , SB202190 ( 349 , 508 , 515 , 518 ) , SB203580 ( 189 , 302 , 462 , 505 ) , SCF ( 210 , 214 , 368 , 484 ) , seliciclib ( 448 , 458 ) , semaxanib ( 365 ) , serum ( 189 , 221 , 380 , 408 , 452 , 476 , 509 , 516 , 518 ) , serum_withdrawal ( 487 ) , silibinin ( 287 ) , silymarin ( 287 ) , siRNA ( 306 , 314 , 369 ) , SKF38393 ( 483 ) , SKF82958 ( 465 ) , SL0101 ( 302 ) , SL327 ( 409 ) , SMI11293 ( 143 ) , sorbitol ( 522 ) , SP600125 ( 457 ) , sphingomyelin ( 42 ) , sphingosine_1-phosphate ( 36 , 113 ) , SPT ( 309 ) , staurosporine ( 343 ) , streptozotocin ( 372 ) , SU5402 ( 371 ) , SU6656 ( 360 ) , sunitinib ( 365 ) , TAK1_inhibitor ( 43 ) , TCAP-1 ( 66 ) , TCDD ( 352 ) , TDZD-8 ( 154 ) , TGF-alpha ( 499 ) , TGF-beta ( 43 , 61 , 92 , 283 , 512 ) , Theophylline ( 309 ) , thrombin ( 90 , 397 , 484 ) , thrombospondin ( 445 ) , TNF ( 88 , 302 , 316 , 346 , 419 , 517 ) , topotecan ( 53 ) , triciribine ( 106 ) , TTX ( 447 ) , TUG-891 ( 19 ) , U0126 ( 59 , 61 , 66 , 89 , 92 , 104 , 116 , 128 , 132 , 152 , 158 , 179 , 189 , 200 , 204 , 222 , 274 , 284 , 307 , 309 , 313 , 352 , 368 , 371 , 381 , 387 , 404 , 408 , 436 , 446 , 448 , 449 , 484 , 486 , 487 , 488 , 493 , 502 , 515 ) , urethane ( 95 ) , UV ( 379 , 441 , 471 , 485 , 495 , 505 , 508 ) , vasopressin ( 186 , 460 ) , VEGF ( 137 ) , visual experience ( 447 ) , vitronectin ( 437 ) , WIN ( 48 ) , wortmannin ( 106 , 132 , 152 , 158 , 313 , 493 , 518 ) , XL-147 ( 13 ) , Y27632 ( 462 ) , YM-254890 ( 19 ) , Zn(2+) ( 143 ) , zymosan ( 515 )

Downstream Regulation
Effects of modification on ERK1:
enzymatic activity, induced ( 75 , 201 , 398 , 404 , 420 , 480 , 499 ) , intracellular localization ( 89 )
Effects of modification on biological processes:
apoptosis, inhibited ( 120 ) , carcinogenesis, induced ( 120 ) , carcinogenesis, inhibited ( 75 ) , cell growth, inhibited ( 75 ) , cytoskeletal reorganization ( 88 ) , neural plasticity ( 103 ) , signaling pathway regulation ( 88 , 89 ) , transcription, altered ( 515 ) , transcription, induced ( 33 )

Disease / Diagnostics Relevance
Relevant diseases:
cancer, squamous cell carcinoma ( 155 )

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Ren H (2011) CST Curation Set: 12902; Year: 2011; Biosample/Treatment: /untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

80

Ren H (2011) CST Curation Set: 12903; Year: 2011; Biosample/Treatment: /untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

81

Ren H (2011) CST Curation Set: 12904; Year: 2011; Biosample/Treatment: /untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

82

Ren H (2011) CST Curation Set: 12894; Year: 2011; Biosample/Treatment: primary cells, B lymphocyte/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

83

Ren H (2011) CST Curation Set: 12895; Year: 2011; Biosample/Treatment: /untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

84

Ren H (2011) CST Curation Set: 12896; Year: 2011; Biosample/Treatment: /untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

85

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Ben P, et al. (2011) Curcumin promotes degradation of inducible nitric oxide synthase and suppresses its enzyme activity in RAW 264.7 cells. Int Immunopharmacol 11, 179-86
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Peidis P, et al. (2011) Doxorubicin bypasses the cytoprotective effects of eIF2α phosphorylation and promotes PKR-mediated cell death. Cell Death Differ 18, 145-54
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Driessens G, et al. (2011) Beta-catenin inhibits T cell activation by selective interference with linker for activation of T cells-phospholipase C-γ1 phosphorylation. J Immunol 186, 784-90
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Wu Z, et al. (2010) MAPK phosphatase-3 promotes hepatic gluconeogenesis through dephosphorylation of forkhead box O1 in mice. J Clin Invest 120, 3901-11
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Bartolomé A, Guillén C, Benito M (2010) Role of the TSC1-TSC2 complex in the integration of insulin and glucose signaling involved in pancreatic beta-cell proliferation. Endocrinology 151, 3084-94
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Zhou J (2010) CST Curation Set: 9105; Year: 2010; Biosample/Treatment: cell line, F9/untreated; Disease: testicular cancer; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-102) Cat#: 9416
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147

Zhou J (2010) CST Curation Set: 9104; Year: 2010; Biosample/Treatment: cell line, ES J1/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-102) Cat#: 9416
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148

Zhou J (2010) CST Curation Set: 9109; Year: 2010; Biosample/Treatment: cell line, P19/untreated; Disease: testicular cancer; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-102) Cat#: 9416
Curated Info

149

Zhou J (2010) CST Curation Set: 9108; Year: 2010; Biosample/Treatment: cell line, PY2/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-102) Cat#: 9416
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150

Racaniello M, et al. (2010) Phosphorylation changes of CaMKII, ERK1/2, PKB/Akt kinases and CREB activation during early long-term potentiation at Schaffer collateral-CA1 mouse hippocampal synapses. Neurochem Res 35, 239-46
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Park YK, Park H (2010) Prevention of CCAAT/enhancer-binding protein beta DNA binding by hypoxia during adipogenesis. J Biol Chem 285, 3289-99
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Quoyer J, et al. (2010) GLP-1 mediates antiapoptotic effect by phosphorylating Bad through a beta-arrestin 1-mediated ERK1/2 activation in pancreatic beta-cells. J Biol Chem 285, 1989-2002
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Liron T, Nahari T, Souroujon MC, Neumann D (2010) Insertion of an NPVY sequence into the cytosolic domain of the erythropoietin receptor selectively affects erythropoietin-mediated signalling and function. Biochem J 427, 305-12
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Aguilar-Morante D, et al. (2010) Inhibition of glioblastoma growth by the thiadiazolidinone compound TDZD-8. PLoS One 5, e13879
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Zhao L, et al. (2009) Srcasm inhibits Fyn-induced cutaneous carcinogenesis with modulation of Notch1 and p53. Cancer Res 69, 9439-47
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156

Tucker M (2009) CST Curation Set: 8605; Year: 2009; Biosample/Treatment: cell line, embryonic stem cells (mouse)(PTEN)/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: p[ST]P
Curated Info

157

Tucker M (2009) CST Curation Set: 8602; Year: 2009; Biosample/Treatment: cell line, embryonic stem cells (mouse)(PTEN)/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: p[ST]P
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158

Salmond RJ, Emery J, Okkenhaug K, Zamoyska R (2009) MAPK, phosphatidylinositol 3-kinase, and mammalian target of rapamycin pathways converge at the level of ribosomal protein S6 phosphorylation to control metabolic signaling in CD8 T cells. J Immunol 183, 7388-97
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Browne CD, et al. (2009) Suppression of phosphatidylinositol 3,4,5-trisphosphate production is a key determinant of B cell anergy. Immunity 31, 749-60
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160

Tucker M (2009) CST Curation Set: 8089; Year: 2009; Biosample/Treatment: cell line, embryonic stem cells (mouse)(PTEN)/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
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161

Tucker M (2009) CST Curation Set: 8084; Year: 2009; Biosample/Treatment: cell line, embryonic stem cells (mouse)(PTEN)/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

162

Tucker M (2009) CST Curation Set: 8081; Year: 2009; Biosample/Treatment: cell line, embryonic stem cells (mouse)(PTEN)/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

163

Tucker M (2009) CST Curation Set: 8088; Year: 2009; Biosample/Treatment: cell line, embryonic stem cells (mouse)(PTEN)/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

164

Tucker M (2009) CST Curation Set: 8077; Year: 2009; Biosample/Treatment: cell line, embryonic stem cells (mouse)(PTEN)/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: p[STY] Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine (P-Tyr-1000) Rabbit mAb Cat#: 8954, Phospho-Tyrosine Rabbit mAb (p-Tyr-1000) Immunoaffinity Beads Cat#: 8876
Curated Info

165

Tucker M (2009) CST Curation Set: 8085; Year: 2009; Biosample/Treatment: cell line, embryonic stem cells (mouse)(PTEN)/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

166

Tucker M (2009) CST Curation Set: 8080; Year: 2009; Biosample/Treatment: cell line, embryonic stem cells (mouse)(PTEN)/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

167

Tucker M (2009) CST Curation Set: 8072; Year: 2009; Biosample/Treatment: cell line, embryonic stem cells (mouse)(PTEN)/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: p[STY] Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine (P-Tyr-1000) Rabbit mAb Cat#: 8954, Phospho-Tyrosine Rabbit mAb (p-Tyr-1000) Immunoaffinity Beads Cat#: 8876
Curated Info

168

Guo A (2009) CST Curation Set: 8168; Year: 2009; Biosample/Treatment: tissue, testis/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: (F/Y/M)Xp[ST](L/I/M)
Curated Info

169

Guo A (2009) CST Curation Set: 8166; Year: 2009; Biosample/Treatment: tissue, spleen/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: (F/Y/M)Xp[ST](L/I/M)
Curated Info

170

Guo A (2009) CST Curation Set: 8170; Year: 2009; Biosample/Treatment: tissue, thymus/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: (F/Y/M)Xp[ST](L/I/M)
Curated Info

171

Guo A (2009) CST Curation Set: 8167; Year: 2009; Biosample/Treatment: tissue, testis/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: (F/Y/M)Xp[ST](L/I/M)
Curated Info

172

Guo A (2009) CST Curation Set: 8169; Year: 2009; Biosample/Treatment: tissue, thymus/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: (F/Y/M)Xp[ST](L/I/M)
Curated Info

173

Guo A (2009) CST Curation Set: 8165; Year: 2009; Biosample/Treatment: tissue, spleen/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: (F/Y/M)Xp[ST](L/I/M)
Curated Info

174

McPherson VA, et al. (2009) SH2 domain-containing phosphatase-2 protein-tyrosine phosphatase promotes Fc(epsilon)RI-induced activation of Fyn and Erk pathways leading to TNF(alpha) release from bone marrow-derived mast cells. J Immunol 183, 4940-7
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175

Santamaría E, et al. (2009) Regulation of stathmin phosphorylation in mouse liver progenitor-29 cells during proteasome inhibition. Proteomics 9, 4495-506
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176

Guo A (2009) CST Curation Set: 7710; Year: 2009; Biosample/Treatment: tissue, thymus/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

177

Guo A (2009) CST Curation Set: 7709; Year: 2009; Biosample/Treatment: tissue, testis/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

178

Guo A (2009) CST Curation Set: 7708; Year: 2009; Biosample/Treatment: tissue, spleen/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
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179

Joshi S, et al. (2009) Type I interferon (IFN)-dependent activation of Mnk1 and its role in the generation of growth inhibitory responses. Proc Natl Acad Sci U S A 106, 12097-102
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180

Zhou J (2009) CST Curation Set: 7383; Year: 2009; Biosample/Treatment: tissue, brain/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: QXp[ST]
Curated Info

181

Moritz A (2009) CST Curation Set: 7223; Year: 2009; Biosample/Treatment: cell line, BaF3/serum starved; Disease: chronic myelogenous leukemia; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

182

Possemato A (2009) CST Curation Set: 7168; Year: 2009; Biosample/Treatment: cell line, RAW 264.7/LPS; Disease: leukemia; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

183

Possemato A (2009) CST Curation Set: 7169; Year: 2009; Biosample/Treatment: cell line, RAW 264.7/MG132; Disease: leukemia; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

184

Possemato A (2009) CST Curation Set: 7167; Year: 2009; Biosample/Treatment: cell line, RAW 264.7/LPS; Disease: leukemia; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

185

Possemato A (2009) CST Curation Set: 7166; Year: 2009; Biosample/Treatment: cell line, RAW 264.7/control; Disease: leukemia; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
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186

Sinnett-Smith J, et al. (2009) Protein Kinase D Mediates Mitogenic Signaling by Gq-coupled Receptors through Protein Kinase C-independent Regulation of Activation Loop Ser744 and Ser748 Phosphorylation. J Biol Chem 284, 13434-45
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Lee DH, et al. (2009) Targeted disruption of ROCK1 causes insulin resistance in vivo. J Biol Chem 284, 11776-80
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Chung BM, et al. (2009) The role of cooperativity with Src in oncogenic transformation mediated by non-small cell lung cancer-associated EGF receptor mutants. Oncogene 28, 1821-32
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Tucker DE, et al. (2009) Role of Phosphorylation and Basic Residues in the Catalytic Domain of Cytosolic Phospholipase A2{alpha} in Regulating Interfacial Kinetics and Binding and Cellular Function. J Biol Chem 284, 9596-611
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Furusawa J, et al. (2009) Glycyrrhiza inflata-derived chalcones, Licochalcone A, Licochalcone B and Licochalcone D, inhibit phosphorylation of NF-kappaB p65 in LPS signaling pathway. Int Immunopharmacol 9, 499-507
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191

Li Y (2009) CST Curation Set: 6302; Year: 2009; Biosample/Treatment: cell line, MEDF Ras V12 HDAC6-/+/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

192

Li Y (2009) CST Curation Set: 6303; Year: 2009; Biosample/Treatment: cell line, MEDF Ras V12 HDAC6-/+/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

193

Li Y (2009) CST Curation Set: 6297; Year: 2009; Biosample/Treatment: cell line, MEF/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

194

Li Y (2009) CST Curation Set: 6298; Year: 2009; Biosample/Treatment: cell line, MEF Ras v12/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

195

Li Y (2009) CST Curation Set: 6299; Year: 2009; Biosample/Treatment: cell line, MEF Ras v12/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

196

Li Y (2009) CST Curation Set: 6296; Year: 2009; Biosample/Treatment: cell line, MEF/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

197

Catalanotti F, et al. (2009) A Mek1-Mek2 heterodimer determines the strength and duration of the Erk signal. Nat Struct Mol Biol 16, 294-303
19219045   Curated Info

198

Olson LE, Soriano P (2009) Increased PDGFRalpha activation disrupts connective tissue development and drives systemic fibrosis. Dev Cell 16, 303-13
19217431   Curated Info

199

Das M, et al. (2009) Induction of hepatitis by JNK-mediated expression of TNF-alpha. Cell 136, 249-60
19167327   Curated Info

200

van Gorp AG, et al. (2009) AGC kinases regulate phosphorylation and activation of eukaryotic translation initiation factor 4B. Oncogene 28, 95-106
18836482   Curated Info

201

Tallent MK, et al. (2009) In vivo modulation of O-GlcNAc levels regulates hippocampal synaptic plasticity through interplay with phosphorylation. J Biol Chem 284, 174-81
19004831   Curated Info

202

McPherson VA, et al. (2009) Contributions of F-BAR and SH2 domains of Fes protein tyrosine kinase for coupling to the FcepsilonRI pathway in mast cells. Mol Cell Biol 29, 389-401
19001085   Curated Info

203

Lorenz K, Schmitt JP, Schmitteckert EM, Lohse MJ (2009) A new type of ERK1/2 autophosphorylation causes cardiac hypertrophy. Nat Med 15, 75-83
19060905   Curated Info

204

Conche C, Boulla G, Trautmann A, Randriamampita C (2009) T cell adhesion primes antigen receptor-induced calcium responses through a transient rise in adenosine 3',5'-cyclic monophosphate. Immunity 30, 33-43
19144315   Curated Info

205

Zanivan S, et al. (2008) Solid tumor proteome and phosphoproteome analysis by high resolution mass spectrometry. J Proteome Res 7, 5314-26
19367708   Curated Info

206

Stokes M (2008) CST Curation Set: 5664; Year: 2008; Biosample/Treatment: tissue, heart/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

207

Stokes M (2008) CST Curation Set: 5665; Year: 2008; Biosample/Treatment: tissue, heart/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

208

Stokes M (2008) CST Curation Set: 5666; Year: 2008; Biosample/Treatment: cell line, Noonan Syndrome mouse heart/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

209

Stokes M (2008) CST Curation Set: 5667; Year: 2008; Biosample/Treatment: cell line, Noonan Syndrome mouse heart/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

210

Simon C, et al. (2008) Lnk adaptor protein down-regulates specific Kit-induced signaling pathways in primary mast cells. Blood 112, 4039-47
18753636   Curated Info

211

Kaneda T, et al. (2008) Mutation of Y925F in focal adhesion kinase (FAK) suppresses melanoma cell proliferation and metastasis. Cancer Lett 270, 354-61
18606490   Curated Info

212

Mariappan MM, et al. (2008) Glycogen synthase kinase 3beta is a novel regulator of high glucose- and high insulin-induced extracellular matrix protein synthesis in renal proximal tubular epithelial cells. J Biol Chem 283, 30566-75
18701453   Curated Info

213

Bécart S, et al. (2008) Tyrosine-phosphorylation-dependent translocation of the SLAT protein to the immunological synapse is required for NFAT transcription factor activation. Immunity 29, 704-19
18976935   Curated Info

214

Samayawardhena LA, Pallen CJ (2008) Protein-tyrosine phosphatase alpha regulates stem cell factor-dependent c-Kit activation and migration of mast cells. J Biol Chem 283, 29175-85
18725415   Curated Info

215

Partovian C, et al. (2008) Syndecan-4 regulates subcellular localization of mTOR Complex2 and Akt activation in a PKCalpha-dependent manner in endothelial cells. Mol Cell 32, 140-9
18851840   Curated Info

216

Rikova K (2008) CST Curation Set: 5291; Year: 2008; Biosample/Treatment: cell line, Dana Farber-S1/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: p[ST]Q
Curated Info

217

Rikova K (2008) CST Curation Set: 5292; Year: 2008; Biosample/Treatment: cell line, Dana Farber-S2/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: p[ST]Q
Curated Info

218

Rikova K (2008) CST Curation Set: 5293; Year: 2008; Biosample/Treatment: cell line, Dana Farber-S3/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: p[ST]Q
Curated Info

219

Rikova K (2008) CST Curation Set: 5296; Year: 2008; Biosample/Treatment: cell line, Dana Farber-KTL(LN)-4/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: p[ST]Q
Curated Info

220

Mertins P, et al. (2008) Investigation of protein-tyrosine phosphatase 1B function by quantitative proteomics. Mol Cell Proteomics 7, 1763-77
18515860   Curated Info

221

Noble C, et al. (2008) CRAF autophosphorylation of serine 621 is required to prevent its proteasome-mediated degradation. Mol Cell 31, 862-72
18922468   Curated Info

222

Encinas M, et al. (2008) Analysis of Ret knockin mice reveals a critical role for IKKs, but not PI 3-K, in neurotrophic factor-induced survival of sympathetic neurons. Cell Death Differ 15, 1510-21
18497757   Curated Info

223

Hermann-Kleiter N, et al. (2008) The nuclear orphan receptor NR2F6 suppresses lymphocyte activation and T helper 17-dependent autoimmunity. Immunity 29, 205-16
18701084   Curated Info

224

Rikova K (2008) CST Curation Set: 4985; Year: 2008; Biosample/Treatment: tissue, lung/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

225

Tchivilev I, et al. (2008) Identification of a protective role for protein phosphatase 1cgamma1 against oxidative stress-induced vascular smooth muscle cell apoptosis. J Biol Chem 283, 22193-205
18540044   Curated Info

226

Possemato A (2008) CST Curation Set: 4930; Year: 2008; Biosample/Treatment: cell line, C2C12/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

227

Possemato A (2008) CST Curation Set: 4931; Year: 2008; Biosample/Treatment: cell line, C2C12/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

228

Possemato A (2008) CST Curation Set: 4932; Year: 2008; Biosample/Treatment: cell line, C2C12/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

229

Possemato A (2008) CST Curation Set: 4933; Year: 2008; Biosample/Treatment: cell line, C2C12/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

230

Possemato A (2008) CST Curation Set: 4934; Year: 2008; Biosample/Treatment: cell line, C2C12/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

231

Possemato A (2008) CST Curation Set: 4935; Year: 2008; Biosample/Treatment: cell line, C2C12/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

232

Possemato A (2008) CST Curation Set: 4936; Year: 2008; Biosample/Treatment: cell line, C2C12/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

233

Possemato A (2008) CST Curation Set: 4929; Year: 2008; Biosample/Treatment: cell line, C2C12/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

234

Luo W, et al. (2008) Global impact of oncogenic Src on a phosphotyrosine proteome. J Proteome Res 7, 3447-60
18563927   Curated Info

235

Stokes M (2008) CST Curation Set: 4847; Year: 2008; Biosample/Treatment: tissue, heart/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

236

Rikova K (2008) CST Curation Set: 4790; Year: 2008; Biosample/Treatment: cell line, Dana Farber-KT-1/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

237

Rikova K (2008) CST Curation Set: 4773; Year: 2008; Biosample/Treatment: cell line, Dana Farber-KTL-3/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

238

Rikova K (2008) CST Curation Set: 4775; Year: 2008; Biosample/Treatment: cell line, Dana Farber-KTL(LN)-4/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

239

Rikova K (2008) CST Curation Set: 4788; Year: 2008; Biosample/Treatment: cell line, Dana Farber-KTL(LN)-5/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

240

Rikova K (2008) CST Curation Set: 4769; Year: 2008; Biosample/Treatment: cell line, Dana Farber-S3/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

241

Rikova K (2008) CST Curation Set: 4771; Year: 2008; Biosample/Treatment: cell line, Dana Farber-KTL-1/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

242

Rikova K (2008) CST Curation Set: 4839; Year: 2008; Biosample/Treatment: cell line, Dana Farber-S1/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

243

Rikova K (2008) CST Curation Set: 4840; Year: 2008; Biosample/Treatment: cell line, Dana Farber-S2/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

244

Rikova K (2008) CST Curation Set: 4838; Year: 2008; Biosample/Treatment: cell line, Dana Farber-L2/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

245

Rikova K (2008) CST Curation Set: 4761; Year: 2008; Biosample/Treatment: cell line, Dana Farber-L2/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

246

Rikova K (2008) CST Curation Set: 4763; Year: 2008; Biosample/Treatment: cell line, Dana Farber-S1/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

247

Rikova K (2008) CST Curation Set: 4765; Year: 2008; Biosample/Treatment: cell line, Dana Farber-S2/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

248

Cha HC, et al. (2008) Phosphorylation of CCAAT/enhancer-binding protein alpha regulates GLUT4 expression and glucose transport in adipocytes. J Biol Chem 283, 18002-11
18408001   Curated Info

249

Li Y (2008) CST Curation Set: 4544; Year: 2008; Biosample/Treatment: cell line, 10T1/2/FGF; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

250

Li Y (2008) CST Curation Set: 4543; Year: 2008; Biosample/Treatment: cell line, 10T1/2/FGF; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

251

Li Y (2008) CST Curation Set: 4542; Year: 2008; Biosample/Treatment: cell line, 10T1/2/FGF; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

252

Li Y (2008) CST Curation Set: 4541; Year: 2008; Biosample/Treatment: cell line, 10T1/2/control; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

253

Rikova K (2008) CST Curation Set: 4476; Year: 2008; Biosample/Treatment: cell line, MD Ander 1158(393P)/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

254

Rikova K (2008) CST Curation Set: 4481; Year: 2008; Biosample/Treatment: cell line, MD Ander a0859/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

255

Oneyama C, et al. (2008) The lipid raft-anchored adaptor protein Cbp controls the oncogenic potential of c-Src. Mol Cell 30, 426-36
18498747   Curated Info

256

Rikova K (2008) CST Curation Set: 4477; Year: 2008; Biosample/Treatment: cell line, MD Ander 1154/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

257

Rikova K (2008) CST Curation Set: 4478; Year: 2008; Biosample/Treatment: cell line, MD Ander 0895/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

258

Rikova K (2008) CST Curation Set: 4479; Year: 2008; Biosample/Treatment: cell line, MD Ander 1202(344SQ)/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

259

Rikova K (2008) CST Curation Set: 4480; Year: 2008; Biosample/Treatment: cell line, MD Ander 1249/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

260

Rikova K (2008) CST Curation Set: 4474; Year: 2008; Biosample/Treatment: cell line, MD Ander 393LN/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

261

Rikova K (2008) CST Curation Set: 4475; Year: 2008; Biosample/Treatment: cell line, MD Ander 1169/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

262

Rikova K (2008) CST Curation Set: 4437; Year: 2008; Biosample/Treatment: tissue, lung/untreated; Disease: non-small cell lung cancer; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

263

Rikova K (2008) CST Curation Set: 4438; Year: 2008; Biosample/Treatment: tissue, lung/untreated; Disease: non-small cell lung cancer; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

264

Rikova K (2008) CST Curation Set: 4439; Year: 2008; Biosample/Treatment: tissue, lung/untreated; Disease: non-small cell lung cancer; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

265

Rikova K (2008) CST Curation Set: 4440; Year: 2008; Biosample/Treatment: tissue, lung/untreated; Disease: non-small cell lung cancer; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

266

Bayascas JR, et al. (2008) Mutation of the PDK1 PH domain inhibits protein kinase B/Akt, leading to small size and insulin resistance. Mol Cell Biol 28, 3258-72
18347057   Curated Info

267

Ren H (2008) CST Curation Set: 4335; Year: 2008; Biosample/Treatment: cell line, EGFR_WT/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

268

Ren H (2008) CST Curation Set: 4336; Year: 2008; Biosample/Treatment: cell line, EGFR_M/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

269

Ren H (2008) CST Curation Set: 4337; Year: 2008; Biosample/Treatment: cell line, Ras_WT/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

270

Zhou J (2008) CST Curation Set: 4322; Year: 2008; Biosample/Treatment: tissue, brain/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY
Curated Info

271

Zhou J (2008) CST Curation Set: 4323; Year: 2008; Biosample/Treatment: tissue, brain/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY
Curated Info

272

Zhou J (2008) CST Curation Set: 4324; Year: 2008; Biosample/Treatment: tissue, heart/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY
Curated Info

273

Zhou J (2008) CST Curation Set: 4325; Year: 2008; Biosample/Treatment: tissue, liver/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY
Curated Info

274

Yasuda T, et al. (2008) Erk kinases link pre-B cell receptor signaling to transcriptional events required for early B cell expansion. Immunity 28, 499-508
18356083   Curated Info

275

Wernig G, et al. (2008) Efficacy of TG101348, a selective JAK2 inhibitor, in treatment of a murine model of JAK2V617F-induced polycythemia vera. Cancer Cell 13, 311-20
18394554   Curated Info

276

Rikova K (2008) CST Curation Set: 4249; Year: 2008; Biosample/Treatment: tissue, lung/untreated; Disease: non-small cell lung cancer; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

277

Rikova K (2008) CST Curation Set: 4250; Year: 2008; Biosample/Treatment: tissue, lung/Tarceva; Disease: non-small cell lung cancer; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

278

Rikova K (2008) CST Curation Set: 4251; Year: 2008; Biosample/Treatment: tissue, lung/untreated; Disease: non-small cell lung cancer; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

279

Rikova K (2008) CST Curation Set: 4252; Year: 2008; Biosample/Treatment: tissue, lung/untreated; Disease: non-small cell lung cancer; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

280

Rikova K (2008) CST Curation Set: 4253; Year: 2008; Biosample/Treatment: tissue, lung/Tarceva; Disease: non-small cell lung cancer; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

281

Rikova K (2008) CST Curation Set: 4254; Year: 2008; Biosample/Treatment: tissue, lung/untreated; Disease: non-small cell lung cancer; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

282

Bakker W, et al. (2008) Protein kinase C theta activation induces insulin-mediated constriction of muscle resistance arteries. Diabetes 57, 706-13
18086904   Curated Info

283

Samarakoon R, Higgins SP, Higgins CE, Higgins PJ (2008) TGF-beta1-induced plasminogen activator inhibitor-1 expression in vascular smooth muscle cells requires pp60(c-src)/EGFR(Y845) and Rho/ROCK signaling. J Mol Cell Cardiol 44, 527-38
18255094   Curated Info

284

Alejandro EU, Johnson JD (2008) Inhibition of Raf-1 alters multiple downstream pathways to induce pancreatic beta-cell apoptosis. J Biol Chem 283, 2407-17
18006502   Curated Info

285

Takatori A, et al. (2008) Differential transmission of MEKK1 morphogenetic signals by JNK1 and JNK2. Development 135, 23-32
18032450   Curated Info

286

Ballif BA, Carey GR, Sunyaev SR, Gygi SP (2008) Large-scale identification and evolution indexing of tyrosine phosphorylation sites from murine brain. J Proteome Res 7, 311-8
18034455   Curated Info

287

Tyagi A, et al. (2007) Chemopreventive effects of silymarin and silibinin on N-butyl-N-(4-hydroxybutyl) nitrosamine induced urinary bladder carcinogenesis in male ICR mice. Mol Cancer Ther 6, 3248-55
18089718   Curated Info

288

Hu HJ, et al. (2007) Metabotropic glutamate receptor 5 modulates nociceptive plasticity via extracellular signal-regulated kinase-Kv4.2 signaling in spinal cord dorsal horn neurons. J Neurosci 27, 13181-91
18045912   Curated Info

289

Ramshaw HS, et al. (2007) The Shc-binding site of the {beta}c subunit of the GM-CSF/IL-3/IL-5 receptors is a negative regulator of hematopoiesis. Blood 110, 3582-90
17638849   Curated Info

290

Cao L, et al. (2007) Quantitative time-resolved phosphoproteomic analysis of mast cell signaling. J Immunol 179, 5864-76
17947660   Curated Info

291

Gu T (2007) CST Curation Set: 3402; Year: 2007; Biosample/Treatment: cell line, Baf3(MSCV-NEO)/IL3 withdrawal; Disease: chronic myelogenous leukemia; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

292

Gu T (2007) CST Curation Set: 3403; Year: 2007; Biosample/Treatment: cell line, Baf3(MSCV-NEO)/IL3 withdrawal; Disease: chronic myelogenous leukemia; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

293

Gu T (2007) CST Curation Set: 3404; Year: 2007; Biosample/Treatment: cell line, Baf3(MSCV-NEO-FLT3/ITD)/IL3 withdrawal; Disease: chronic myelogenous leukemia; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

294

Gu T (2007) CST Curation Set: 3405; Year: 2007; Biosample/Treatment: cell line, Baf3(MSCV-NEO-FLT3/ITD)/IL3 withdrawal; Disease: chronic myelogenous leukemia; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

295

Gu T (2007) CST Curation Set: 3406; Year: 2007; Biosample/Treatment: cell line, Baf3(PLXSN-NEO-FLT3/ITD)/IL3 withdrawal; Disease: chronic myelogenous leukemia; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

296

Gu T (2007) CST Curation Set: 3407; Year: 2007; Biosample/Treatment: cell line, Baf3(PLXSN-NEO-FLT3/ITD)/IL3 withdrawal; Disease: chronic myelogenous leukemia; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

297

Gu T (2007) CST Curation Set: 3408; Year: 2007; Biosample/Treatment: cell line, Baf3(PLXSN-NEO-FLT3 (D835Y))/IL3 withdrawal; Disease: chronic myelogenous leukemia; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

298

Gu T (2007) CST Curation Set: 3409; Year: 2007; Biosample/Treatment: cell line, Baf3(PLXSN-NEO-FLT3 (D835Y))/IL3 withdrawal; Disease: chronic myelogenous leukemia; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

299

Schenning M, van Tiel CM, Wirtz KW, Snoek GT (2007) The anti-apoptotic MAP kinase pathway is inhibited in NIH3T3 fibroblasts with increased expression of phosphatidylinositol transfer protein beta. Biochim Biophys Acta 1773, 1664-71
17683809   Curated Info

300

Robinson MJ, et al. (2007) Phosphorylation of TPL-2 on serine 400 is essential for lipopolysaccharide activation of extracellular signal-regulated kinase in macrophages. Mol Cell Biol 27, 7355-64
17709378   Curated Info

301

Le Y, et al. (2007) SOCS3 protein developmentally regulates the chemokine receptor CXCR4-FAK signaling pathway during B lymphopoiesis. Immunity 27, 811-23
18031698   Curated Info

302

Zaru R, et al. (2007) The MAPK-activated kinase Rsk controls an acute Toll-like receptor signaling response in dendritic cells and is activated through two distinct pathways. Nat Immunol 8, 1227-35
17906627   Curated Info

303

Yu J (2007) CST Curation Set: 3379; Year: 2007; Biosample/Treatment: cell line, Mouse Mesenchymal Stem Cells/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

304

Yu J (2007) CST Curation Set: 3380; Year: 2007; Biosample/Treatment: cell line, Mouse Mesenchymal Stem Cells/bFGF; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

305

Yamanaka A, et al. (2007) Involvement of CaM kinase II in gonadotropin-releasing hormone-induced activation of MAP kinase in cultured hypothalamic neurons. Arch Biochem Biophys 466, 234-41
17706588   Curated Info

306

Cho YY, et al. (2007) Ribosomal S6 kinase 2 is a key regulator in tumor promoter induced cell transformation. Cancer Res 67, 8104-12
17804722   Curated Info

307

Falin RA, Cotton CU (2007) Acute downregulation of ENaC by EGF involves the PY motif and putative ERK phosphorylation site. J Gen Physiol 130, 313-28
17724164   Curated Info

308

McNeill L, et al. (2007) The differential regulation of Lck kinase phosphorylation sites by CD45 is critical for T cell receptor signaling responses. Immunity 27, 425-37
17719247   Curated Info

309

Merla R, et al. (2007) The central role of adenosine in statin-induced ERK1/2, Akt, and eNOS phosphorylation. Am J Physiol Heart Circ Physiol 293, H1918-28
17616749   Curated Info

310

Jaeschke A, Davis RJ (2007) Metabolic stress signaling mediated by mixed-lineage kinases. Mol Cell 27, 498-508
17679097   Curated Info

311

Xuan YT, et al. (2007) Endothelial nitric oxide synthase plays an obligatory role in the late phase of ischemic preconditioning by activating the protein kinase C epsilon p44/42 mitogen-activated protein kinase pSer-signal transducers and activators of transcription1/3 pathway. Circulation 116, 535-44
17606840   Curated Info

312

Li X, et al. (2007) Role of cdk2 in the sequential phosphorylation/activation of C/EBPbeta during adipocyte differentiation. Proc Natl Acad Sci U S A 104, 11597-602
17601773   Curated Info

313

Dong S, et al. (2007) 14-3-3 Integrates prosurvival signals mediated by the AKT and MAPK pathways in ZNF198-FGFR1-transformed hematopoietic cells. Blood 110, 360-9
17389761   Curated Info

314

Yoshizaki T, et al. (2007) Myosin 5a is an insulin-stimulated Akt2 (protein kinase Bbeta) substrate modulating GLUT4 vesicle translocation. Mol Cell Biol 27, 5172-83
17515613   Curated Info

315

Takeshita S, et al. (2007) c-Fms tyrosine 559 is a major mediator of M-CSF-induced proliferation of primary macrophages. J Biol Chem 282, 18980-90
17420255   Curated Info

316

Schlaepfer DD, et al. (2007) Tumor necrosis factor-alpha stimulates focal adhesion kinase activity required for mitogen-activated kinase-associated interleukin 6 expression. J Biol Chem 282, 17450-9
17438336   Curated Info

317

Guo A (2007) CST Curation Set: 2987; Year: 2007; Biosample/Treatment: tissue, liver/-; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

318

Guo A (2007) CST Curation Set: 2988; Year: 2007; Biosample/Treatment: tissue, liver/-; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

319

Guo A (2007) CST Curation Set: 2989; Year: 2007; Biosample/Treatment: tissue, liver/Insulin; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

320

Guo A (2007) CST Curation Set: 2990; Year: 2007; Biosample/Treatment: tissue, liver/Insulin; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

321

Guo A (2007) CST Curation Set: 2983; Year: 2007; Biosample/Treatment: tissue, liver/-; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

322

Guo A (2007) CST Curation Set: 2984; Year: 2007; Biosample/Treatment: tissue, liver/-; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

323

Guo A (2007) CST Curation Set: 2985; Year: 2007; Biosample/Treatment: tissue, liver/Insulin; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

324

Guo A (2007) CST Curation Set: 2986; Year: 2007; Biosample/Treatment: tissue, liver/Insulin; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

325

Artemenko Y, Gagnon A, Ibrahim S, Sorisky A (2007) Regulation of PDGF-stimulated SHIP2 tyrosine phosphorylation and association with Shc in 3T3-L1 preadipocytes. J Cell Physiol 211, 598-607
17219406   Curated Info

326

Guo A (2007) CST Curation Set: 2923; Year: 2007; Biosample/Treatment: tissue, heart/-; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: p[ST](D/E)X(D/E) Antibodies Used to Purify Peptides prior to LCMS: Phospho(Ser/Thr) CKII Substrate Antibody (polyAb) Cat#: 5808, PTMScan(R) Phospho-CK Substrate Motif (S*/T*D/EXD/E) Immunoaffinity Beads Cat#: 1994
Curated Info

327

Toole BJ, Cohen PT (2007) The skeletal muscle-specific glycogen-targeted protein phosphatase 1 plays a major role in the regulation of glycogen metabolism by adrenaline in vivo. Cell Signal 19, 1044-55
17257813   Curated Info

328

Xing K, et al. (2007) Low molecular weight protein tyrosine phosphatase (LMW-PTP) and its possible physiological functions of redox signaling in the eye lens. Biochim Biophys Acta 1774, 545-55
17428749   Curated Info

329

Guo A (2007) CST Curation Set: 2827; Year: 2007; Biosample/Treatment: tissue, heart/-; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

330

Jo M, et al. (2007) Urokinase receptor primes cells to proliferate in response to epidermal growth factor. Oncogene 26, 2585-94
17043637   Curated Info

331

Li QJ, et al. (2007) miR-181a is an intrinsic modulator of T cell sensitivity and selection. Cell 129, 147-61
17382377   Curated Info

332

Khan N, et al. (2007) Oral consumption of pomegranate fruit extract inhibits growth and progression of primary lung tumors in mice. Cancer Res 67, 3475-82
17389758   Curated Info

333

Guo A (2007) CST Curation Set: 2672; Year: 2007; Biosample/Treatment: tissue, brain/-; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

334

Guo A (2007) CST Curation Set: 2675; Year: 2007; Biosample/Treatment: tissue, brain/LY; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

335

Guo A (2007) CST Curation Set: 2677; Year: 2007; Biosample/Treatment: tissue, brain/-; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: p[ST]Q Antibodies Used to Purify Peptides prior to LCMS: Phospho-(Ser/Thr) ATM/ATR Substrate Antibody Cat#: 2851
Curated Info

336

Guo A (2007) CST Curation Set: 2682; Year: 2007; Biosample/Treatment: tissue, brain/-; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: p[ST]Q Antibodies Used to Purify Peptides prior to LCMS: Phospho-(Ser/Thr) ATM/ATR Substrate Antibody Cat#: 2851
Curated Info

337

Guo A (2007) CST Curation Set: 2564; Year: 2007; Biosample/Treatment: cell line, C2C12-D/-; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

338

Guo A (2007) CST Curation Set: 2565; Year: 2007; Biosample/Treatment: cell line, C2C12-D/Insulin; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

339

Cuthbert PC, et al. (2007) Synapse-associated protein 102/dlgh3 couples the NMDA receptor to specific plasticity pathways and learning strategies. J Neurosci 27, 2673-82
17344405   Curated Info

340

Ikeda Y, Ishiguro K, Fujita SC (2007) Ether stress-induced Alzheimer-like tau phosphorylation in the normal mouse brain. FEBS Lett 581, 891-7
17289030   Curated Info

341

Emre Y, et al. (2007) Mitochondria contribute to LPS-induced MAPK activation via uncoupling protein UCP2 in macrophages. Biochem J 402, 271-8
17073824   Curated Info

342

Andreozzi F, et al. (2007) Interleukin-6 impairs the insulin signaling pathway, promoting production of nitric oxide in human umbilical vein endothelial cells. Mol Cell Biol 27, 2372-83
17242212   Curated Info

343

Hu Y, Kang C, Philp RJ, Li B (2007) PKC delta phosphorylates p52ShcA at Ser29 to regulate ERK activation in response to H2O2. Cell Signal 19, 410-8
16963224   Curated Info

344

Villén J, Beausoleil SA, Gerber SA, Gygi SP (2007) Large-scale phosphorylation analysis of mouse liver. Proc Natl Acad Sci U S A 104, 1488-93
17242355   Curated Info

345

Sahin B, et al. (2007) Evaluation of neuronal phosphoproteins as effectors of caffeine and mediators of striatal adenosine A2A receptor signaling. Brain Res 1129, 1-14
17157277   Curated Info

346

D'Alimonte I, et al. (2007) Guanosine inhibits CD40 receptor expression and function induced by cytokines and beta amyloid in mouse microglia cells. J Immunol 178, 720-31
17202332   Curated Info

347

Ueki Y, et al. (2007) Increased myeloid cell responses to M-CSF and RANKL cause bone loss and inflammation in SH3BP2 "cherubism" mice. Cell 128, 71-83
17218256   Curated Info

348

Blonska M, et al. (2007) The CARMA1-Bcl10 signaling complex selectively regulates JNK2 kinase in the T cell receptor-signaling pathway. Immunity 26, 55-66
17189706   Curated Info

349

Frey MR, Dise RS, Edelblum KL, Polk DB (2006) p38 kinase regulates epidermal growth factor receptor downregulation and cellular migration. EMBO J 25, 5683-92
1713