Thr203
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Site Information
HDHtGFLtEyVAtRW   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 447542

In vivo Characterization
Methods used to characterize site in vivo:
[32P] ATP in vitro ( 241 ) , [32P] bio-synthetic labeling ( 338 , 414 ) , flow cytometry ( 144 , 257 ) , immunoprecipitation ( 5 , 8 , 12 , 36 , 41 , 132 , 169 , 178 , 189 , 241 , 418 ) , mass spectrometry ( 3 , 6 , 7 , 17 , 28 , 43 , 44 , 45 , 46 , 49 , 53 , 55 , 58 , 59 , 61 , 62 , 69 , 70 , 71 , 72 , 73 , 74 , 88 , 89 , 103 , 125 , 126 , 134 , 135 , 136 , 143 , 146 , 147 , 148 , 149 , 150 , 151 , 152 , 153 , 154 , 155 , 156 , 157 , 158 , 161 , 162 , 164 , 165 , 166 , 172 , 173 , 174 , 183 , 184 , 185 , 186 , 187 , 194 , 195 , 196 , 197 , 198 , 202 , 204 , 205 , 206 , 207 , 208 , 209 , 210 , 212 , 213 , 214 , 215 , 216 , 218 , 219 , 220 , 221 , 222 , 224 , 225 , 226 , 228 , 229 , 232 , 233 , 234 , 235 , 236 , 237 , 242 , 246 , 247 , 248 , 253 , 265 , 266 , 267 , 268 , 269 , 270 , 271 , 272 , 274 , 277 , 281 , 282 , 283 , 284 , 285 , 286 , 291 , 316 ) , mass spectrometry (in vitro) ( 128 ) , microscopy-colocalization with upstream kinase ( 393 ) , mutation of modification site ( 5 , 8 , 12 , 189 , 191 , 230 , 239 , 241 , 309 , 312 , 338 , 341 , 342 , 369 ) , peptide sequencing ( 322 ) , phospho-antibody ( 2 , 5 , 8 , 9 , 10 , 11 , 12 , 14 , 15 , 16 , 19 , 21 , 22 , 23 , 25 , 26 , 27 , 29 , 30 , 31 , 32 , 33 , 36 , 37 , 38 , 40 , 41 , 47 , 48 , 51 , 52 , 54 , 56 , 63 , 64 , 65 , 68 , 77 , 83 , 86 , 87 , 90 , 91 , 96 , 97 , 98 , 100 , 101 , 102 , 105 , 106 , 107 , 108 , 109 , 110 , 111 , 112 , 114 , 115 , 117 , 118 , 119 , 120 , 121 , 122 , 123 , 124 , 127 , 129 , 130 , 131 , 132 , 133 , 137 , 138 , 139 , 140 , 141 , 142 , 144 , 145 , 159 , 160 , 163 , 168 , 169 , 170 , 171 , 176 , 177 , 178 , 179 , 180 , 181 , 182 , 188 , 189 , 190 , 191 , 192 , 199 , 200 , 201 , 203 , 217 , 227 , 230 , 231 , 238 , 239 , 240 , 243 , 244 , 245 , 250 , 252 , 254 , 255 , 256 , 257 , 258 , 259 , 260 , 261 , 262 , 264 , 273 , 275 , 276 , 278 , 279 , 280 , 287 , 288 , 289 , 290 , 292 , 293 , 294 , 295 , 296 , 297 , 298 , 299 , 300 , 301 , 302 , 303 , 304 , 305 , 306 , 307 , 308 , 309 , 310 , 311 , 312 , 313 , 314 , 315 , 317 , 318 , 319 , 320 , 321 , 324 , 328 , 329 , 331 , 332 , 333 , 334 , 335 , 336 , 337 , 338 , 339 , 340 , 341 , 342 , 343 , 344 , 345 , 346 , 347 , 348 , 349 , 350 , 351 , 352 , 353 , 354 , 355 , 356 , 357 , 358 , 359 , 360 , 362 , 363 , 364 , 365 , 366 , 367 , 369 , 370 , 371 , 372 , 373 , 374 , 375 , 376 , 377 , 378 , 379 , 380 , 381 , 382 , 383 , 385 , 386 , 387 , 388 , 389 , 390 , 391 , 392 , 393 , 394 , 395 , 396 , 397 , 398 , 399 , 400 , 401 , 402 , 403 , 404 , 405 , 406 , 407 , 408 , 409 , 410 , 411 , 412 , 413 , 414 , 415 , 416 , 418 , 419 , 420 , 421 , 422 ) , phosphopeptide mapping ( 414 ) , western blotting ( 2 , 5 , 8 , 9 , 10 , 11 , 12 , 14 , 15 , 16 , 19 , 21 , 22 , 23 , 25 , 26 , 27 , 29 , 30 , 31 , 32 , 33 , 36 , 37 , 38 , 40 , 41 , 47 , 48 , 51 , 52 , 54 , 56 , 63 , 64 , 65 , 68 , 77 , 83 , 86 , 87 , 90 , 91 , 96 , 97 , 98 , 100 , 101 , 102 , 105 , 106 , 107 , 108 , 109 , 110 , 111 , 112 , 114 , 115 , 117 , 118 , 120 , 121 , 122 , 123 , 124 , 127 , 129 , 130 , 131 , 132 , 133 , 137 , 138 , 139 , 140 , 141 , 142 , 144 , 145 , 159 , 160 , 163 , 168 , 169 , 170 , 171 , 176 , 177 , 178 , 179 , 180 , 181 , 182 , 188 , 189 , 190 , 191 , 192 , 199 , 200 , 201 , 203 , 217 , 227 , 230 , 231 , 238 , 239 , 240 , 241 , 243 , 245 , 250 , 252 , 254 , 255 , 256 , 258 , 259 , 260 , 261 , 262 , 264 , 273 , 275 , 276 , 278 , 279 , 280 , 287 , 288 , 292 , 293 , 294 , 295 , 296 , 297 , 298 , 299 , 300 , 301 , 302 , 303 , 304 , 305 , 306 , 307 , 308 , 309 , 310 , 311 , 312 , 313 , 314 , 317 , 318 , 319 , 320 , 322 , 324 , 328 , 331 , 333 , 335 , 341 , 344 , 345 , 346 , 347 , 348 , 349 , 350 , 351 , 353 , 354 , 355 , 356 , 358 , 359 , 360 , 362 , 363 , 364 , 366 , 369 , 370 , 373 , 374 , 375 , 376 , 377 , 378 , 381 , 382 , 383 , 385 , 386 , 388 , 389 , 390 , 392 , 397 , 400 , 401 , 405 , 406 , 411 , 412 , 413 , 414 , 415 , 416 , 418 , 419 , 420 , 421 , 422 )
Disease tissue studied:
adrenal cancer ( 381 ) , pheochromocytoma ( 381 ) , breast cancer ( 300 , 322 , 413 ) , cervical cancer ( 386 ) , cervical adenocarcinoma ( 386 ) , colorectal cancer ( 356 ) , colorectal carcinoma ( 356 ) , leukemia ( 165 , 166 , 231 , 247 , 248 ) , acute erythroid leukemias, including erythroleukemia (M6a) and very rare pure erythroid leukemia (M6b) ( 231 ) , chronic myelogenous leukemia ( 247 , 248 ) , liver cancer ( 312 ) , lung cancer ( 107 , 224 , 225 , 226 , 228 , 229 , 232 , 233 , 234 , 235 , 236 , 237 , 280 , 303 ) , non-small cell lung cancer ( 107 , 224 , 225 , 226 , 232 , 233 , 234 , 235 , 236 , 237 ) , lymphoma ( 391 ) , B cell lymphoma ( 391 ) , neuroblastoma ( 98 , 354 , 385 ) , pancreatic cancer ( 139 , 240 ) , pancreatic carcinoma ( 139 , 240 ) , melanoma skin cancer ( 63 , 183 , 189 ) , testicular cancer ( 134 , 136 , 358 ) , diabetes mellitus ( 190 , 312 ) , type 2 diabetes ( 190 , 312 ) , Huntington's disease ( 36 ) , Turner-like syndrome ( 186 , 187 )
Relevant cell line - cell type - tissue:
'3T3-L1, differentiated' (adipocyte) ( 6 , 17 , 31 , 45 ) , 'B lymphocyte, precursor' ( 230 ) , 'brain, cerebellum' ( 335 , 412 ) , 'brain, cerebral cortex' ( 5 , 301 , 352 , 407 ) , 'brain, cerebrum' ( 335 , 412 ) , 'brain, embryonic' ( 281 , 283 ) , 'brain, embryonic' [BAG1 (mouse)] ( 330 ) , 'brain, hippocampus' ( 38 , 137 , 179 , 288 , 313 , 367 ) , 'brain, hippocampus' [DLG3 (mouse), homozygous knockout] ( 287 ) , 'brain, hypothalamus, suprachiasmatic nucleus' ( 340 ) , 'brain, striatum' ( 36 , 292 , 334 , 346 , 353 , 360 , 403 ) , 'epithelial, lung' [homozygous knockout] ( 115 ) , 'liver, fetal' ( 311 ) , 'muscle, skeletal' ( 168 , 227 , 275 , 359 ) , 'neuron, cortical'-brain ( 37 , 54 , 132 , 382 , 387 , 396 ) , 'neuron, cortical'-brain [NYAP2 (mouse), homozygous knockout] ( 68 ) , 'neuron, dorsal horn'-spinal cord ( 244 ) , 'neuron, hippocampal'-brain [neurogranin (mouse)] ( 400 ) , 'neuron, superior cervical ganglion' ( 200 ) , 'renal, podocyte' ( 123 ) , 'stem, embryonic' ( 143 , 146 , 147 , 148 , 149 , 150 , 151 , 152 , 227 ) , 'stem, mesenchymal' ( 253 ) , 10T1/2 (fibroblast) ( 212 , 213 , 214 , 371 ) , 293 (epithelial) ( 32 , 181 , 241 , 324 , 341 , 342 , 414 ) , 293T (epithelial) ( 8 , 54 ) , 32D (myeloid) ( 102 , 378 , 419 ) , 3T3 (fibroblast) ( 2 , 43 , 108 , 169 , 178 , 252 , 305 , 309 , 322 , 333 , 355 , 369 , 386 , 389 , 406 , 420 , 421 ) , 3T3 (fibroblast) [CDC42 (human), transfection] ( 43 ) , 3T3 (fibroblast) [INSR (human)] ( 414 ) , 3T3 (fibroblast) [INSR (mouse), transfection] ( 178 ) , 3T3 (fibroblast) [KRas (human), transfection] ( 43 ) , 3T3 (fibroblast) [SHP-2 (mouse), homozygous knockout] ( 321 , 329 , 339 , 341 , 348 , 366 , 376 , 380 , 399 , 422 ) , 3T3 (fibroblast) [Src (human)] ( 303 ) , 3T3-L1 (fibroblast) ( 52 , 86 , 138 , 260 , 262 , 273 , 316 , 370 ) , 4T1 (breast cell) ( 413 ) , AB.1 (T lymphocyte) ( 120 ) , adipocyte-adipose tissue ( 411 ) , adipose tissue ( 227 ) , adipose tissue [DUSP6 (mouse), homozygous knockout] ( 33 ) , alphaT3-1 (pituitary cell) ( 40 ) , artery ( 238 ) , B lymphocyte ( 71 , 230 ) , B lymphocyte-spleen ( 105 , 131 , 295 ) , B lymphocyte-spleen [PTEN (mouse), transgenic] ( 145 ) , B16 (melanocyte) ( 63 ) , B16F1 (melanocyte) ( 189 ) , B16F10 ( 10 ) , BAC1.2F5 (macrophage) ( 402 ) , BaF3 ('B lymphocyte, precursor') ( 47 , 129 , 140 , 178 , 188 , 231 , 247 , 248 , 261 , 298 , 331 , 332 , 378 , 390 ) , BaF3 ('B lymphocyte, precursor') [EGFR (human)] ( 303 ) , BaF3 ('B lymphocyte, precursor') [FLT3 (human)] ( 314 ) , BALB/MK (keratinocyte) ( 418 ) , beta-pancreas ( 139 ) , beta-pancreas [INSR (mouse), transgenic] ( 124 ) , bladder ( 243 ) , BMMC (mast) ( 112 , 415 ) , bone marrow ( 9 , 298 ) , brain ( 58 , 61 , 62 , 126 , 164 , 242 , 282 , 284 , 393 ) , brain [DARPP-32 (mouse), homozygous knockout] ( 349 ) , brain [NYAP2 (mouse), homozygous knockout] ( 68 ) , C2C12 (myoblast) ( 11 , 344 , 373 ) , C2C12-D (muscle cell) ( 285 , 286 ) , C3H10T1/2 (fibroblast) ( 297 ) , CCE ( 351 ) , CHO (fibroblast) ( 8 ) , CMT-93 (intestinal) ( 356 ) , colon ( 118 ) , COS (fibroblast) ( 16 , 47 , 178 , 307 , 355 , 369 , 388 ) , CTL-EN (T lymphocyte) ( 245 ) , dendritic cell ( 252 ) , dendritic cell [MAPKAPK2 (mouse), homozygous knockout] ( 252 ) , dendritic cell [MSK1 (mouse), homozygous knockout] ( 252 ) , E14 ('neuron, hippocampal') ( 56 ) , E14tg2a ('stem, embryonic') ( 351 ) , embryo ( 62 , 311 ) , embryonic ( 48 ) , endothelial-pulmonary artery ( 127 ) , endothelial-vein ( 127 ) , epithelial ( 365 ) , epithelial-'kidney, tubule' ( 256 ) , epithelial-lens ( 276 ) , erythroblast ( 231 ) , ES (stem) ( 32 , 318 , 320 ) , F9 (testicular) ( 134 , 358 ) , Fao (hepatic) ( 312 ) , fibroblast-embryo [BAG1 (mouse)] ( 330 ) , GD25 (fibroblast) ( 375 ) , GL261 (glial) ( 141 ) , GT1-7 (neuron) ( 254 , 315 , 379 ) , HaCaT (keratinocyte) ( 255 ) , heart ( 46 , 181 , 184 , 185 , 186 , 187 , 227 , 258 , 274 , 277 , 299 ) , HEL (erythroid) ( 231 ) , HeLa (cervical) ( 101 ) , HeLa S3 (cervical) ( 386 ) , hepatocyte ( 320 ) , HepG2 (hepatic) ( 312 ) , HT-22 (neuron) ( 387 ) , HT-4 (neuron) ( 387 ) , HUVEC (endothelial) ( 100 ) , IBE (endothelial) ( 392 ) , J774 (macrophage) ( 377 , 397 ) , JB (epithelial) ( 347 , 409 ) , JB6 RT101 (epidermal) ( 319 ) , Jurkat (T lymphocyte) ( 191 ) , keratinocyte-skin [IGF1 (mouse)] ( 324 ) , liver ( 3 , 44 , 55 , 62 , 177 , 227 , 269 , 270 , 271 , 272 , 291 , 312 , 404 ) , liver [Akt2 (mouse), homozygous knockout] ( 265 , 266 , 267 , 268 ) , LLC-PK1 (epithelial) ( 364 ) , lung ( 202 , 224 , 225 , 226 , 280 ) , lung [EGFR (mouse), transgenic] ( 228 ) , lung [HRas (mouse), transgenic] ( 229 ) , lung [p27Kip1 (mouse), genetic knockin] ( 87 ) , macrophage ( 307 ) , macrophage-blood ( 342 ) , macrophage-bone marrow ( 19 , 51 , 125 , 289 , 294 , 336 ) , macrophage-bone marrow [Cot (mouse)] ( 250 ) , macrophage-bone marrow [DUSP1 (mouse), homozygous knockout] ( 125 ) , macrophage-bone marrow [NFkB-p105 (human)] ( 250 ) , macrophage-peritoneum ( 12 , 53 , 97 , 416 ) , mast-bone marrow ( 15 , 121 , 180 , 246 , 295 , 308 , 383 ) , mast-bone marrow [PTPRA (mouse), homozygous knockout] ( 192 ) , mast-bone marrow [SHP-2 (mouse), homozygous knockout] ( 159 ) , MC/9 (mast) ( 378 ) , MCF-7 (breast cell) ( 322 ) , MCP-5 (mast) ( 246 ) , MCT cells (epithelial) ( 190 ) , MEF (fibroblast) ( 12 , 49 , 65 , 101 , 105 , 114 , 163 , 172 , 174 , 198 , 204 , 217 , 239 , 255 , 259 , 264 , 278 , 299 , 304 , 307 , 309 , 310 , 350 , 374 , 409 , 410 ) , MEF (fibroblast) [HRas (mouse), HRas V12] ( 173 ) , MEF (fibroblast) [IGF1R (mouse)] ( 290 , 337 , 343 , 357 ) , MEF (fibroblast) [LKB1 (mouse)] ( 363 ) , MEF (fibroblast) [MSK1 (mouse), homozygous knockout, msk2] ( 405 ) , MEF (fibroblast) [p53 (mouse), homozygous knockout] ( 88 ) , MEF (fibroblast) [PDGFRA (mouse), genetic knockin] ( 176 ) , MEF (fibroblast) [PKR (mouse), homozygous knockout] ( 110 ) , MEF (fibroblast) [PTP1B (mouse), homozygous knockout] ( 198 ) , MEF (fibroblast) [RAF1 (mouse), homozygous knockout] ( 199 ) , MEF (fibroblast) [Raptor (mouse), knockdown] ( 49 ) , MEF (fibroblast) [RICTOR (mouse), knockdown] ( 49 ) , MEF (fibroblast) [TSC2 (mouse), homozygous knockout] ( 89 ) , Mel-Ab (melanocyte) ( 106 ) , mesangial ( 372 ) , microglia ( 293 ) , microvessel endothelial-lung [GIT1 (mouse), homozygous knockout] ( 41 ) , mIMCD-3 (epithelial) ( 401 ) , MIN6 (pancreatic) ( 139 , 240 ) , MLE (epithelial) ( 338 ) , mLEC (epithelial) ( 96 ) , MLO-Y4 (osteoblast) ( 14 ) , MLP-29 ( 160 ) , MS1 (endothelial) ( 344 ) , myeloid ( 294 ) , myeloid-bone marrow ( 231 ) , myocyte-heart ( 30 , 181 , 299 , 328 ) , N18 (neuron) ( 385 ) , Neuro-2a (neuron) ( 98 ) , neuron:postsynaptic density-'brain, hippocampus, CA1 region' ( 7 ) , NMuMG (epithelial) ( 413 ) , NSCLC (pulmonary) ( 107 ) , osteoclast ( 294 ) , P19 (testicular) ( 136 ) , PC-12 (chromaffin) ( 381 ) , platelet-blood ( 119 ) , preosteoclast ( 317 ) , prostate ( 64 ) , R1 ('stem, embryonic') ( 385 ) , R22 ('muscle, smooth') ( 239 ) , RAW 264 (macrophage) ( 342 , 345 ) , RAW 264.7 (macrophage) ( 28 , 109 , 165 , 166 , 171 ) , REF52 (fibroblast) ( 388 ) , SCC16-5 (fibroblast) ( 408 ) , skin ( 371 ) , skin [Fyn (mouse), transgenic] ( 142 ) , skin [mGluR1 (mouse), transgenic, TG mutant mice] ( 183 ) , SN56 (neuron) ( 354 ) , spleen ( 154 , 158 , 162 ) , STC-1 (endocrine) ( 395 ) , stromal ( 91 ) , Swiss 3T3 (fibroblast) ( 362 ) , SYF (fibroblast) ( 122 , 239 , 309 ) , SYF (fibroblast) [Src (mouse), transfection] ( 59 ) , T lymphocyte ( 201 ) , T lymphocyte [FOXO1A (mouse), transgenic] ( 90 ) , T lymphocyte [PELI1 (mouse), homozygous knockout] ( 77 ) , T lymphocyte-blood ( 182 , 257 ) , T lymphocyte-lymph node ( 144 , 279 , 295 ) , T lymphocyte-lymph node [PRKD1 (mouse), genetic knockin] ( 117 ) , T lymphocyte-lymph node [PRKD2 (mouse), genetic knockin] ( 117 ) , T lymphocyte-spleen ( 103 , 111 , 302 ) , T lymphocyte-spleen [LAT (mouse), transgenic] ( 133 ) , T47D (breast cell) ( 300 ) , testis ( 153 , 156 , 161 ) , thymocyte ( 306 ) , thymocyte [CBL (mouse), homozygous knockout] ( 130 ) , thymus ( 155 , 157 ) , thyroid [BRAF (human), genetic knockin] ( 83 ) , uterus ( 21 ) , vascular smooth muscle cell ('muscle, smooth') ( 203 , 239 ) , WEHI-231 (B lymphocyte) ( 391 )

Upstream Regulation
Regulatory protein:
ADRB1 (mouse) ( 46 ) , AIF1 (mouse) ( 23 ) , Akt1 (mouse) ( 415 ) , ALK (human) ( 129 ) , ARAF (human) ( 240 ) , ARAF (mouse) ( 240 ) , ARHGEF7 (mouse) ( 309 ) , ARRB1 (mouse) ( 139 ) , BAG1 (mouse) ( 330 ) , Bcl-10 (mouse) ( 295 ) , BCR-ABL1 (human) ( 303 ) , BRAF (human) ( 200 ) , BRAF (mouse) ( 357 ) , CAMK2D (human) ( 254 ) , CARD11 (mouse) ( 295 ) , CARD9 (mouse) ( 24 ) , CBL (mouse) ( 306 ) , Cbl-b (mouse) ( 306 ) , CD151 (mouse) ( 15 ) , CD44 (mouse) ( 307 ) , CD74 (mouse) ( 307 ) , CDC42 (mouse) ( 43 ) , CDC42 iso1 (mouse) ( 309 ) , CDK5R1 (mouse) ( 346 ) , Cot (mouse) ( 337 ) , dectin-1 (mouse) ( 24 ) , DLG3 (mouse) ( 287 ) , DOK3 (mouse) ( 51 ) , DUSP6 (mouse) ( 33 ) , EAR-2 (mouse) ( 201 ) , EGFR (mouse) ( 239 ) , ERG (mouse) ( 64 ) , ERK2 (mouse) ( 319 ) , FADD (mouse) ( 29 ) , FAK iso2 (mouse) ( 350 , 369 ) , FCER1A (mouse) ( 246 ) , Fes (mouse) ( 180 , 402 ) , FGFR1 (human) ( 261 ) , FMR1 (mouse) ( 5 , 313 ) , FOXP1 (mouse) ( 90 ) , GAB2 (mouse) ( 9 ) , GIPC1 (mouse) ( 127 ) , GIT1 (human) ( 41 ) , GLRX1 (mouse) ( 276 ) , GRB10 (human) ( 47 ) , GRB10 (mouse) ( 20 ) , HePTP (mouse) ( 182 ) , HRas (mouse) ( 65 , 107 , 414 ) , ICMT (mouse) ( 374 ) , IGF1R (mouse) ( 361 ) , IL17RD (mouse) ( 376 ) , IRS1 (mouse) ( 411 ) , ITGA9 (human) ( 298 ) , JAK2 (human) ( 231 , 390 ) , JNK2 (mouse) ( 19 , 65 , 99 ) , KRas (mouse) ( 43 , 64 , 304 , 418 ) , KSR (human) ( 114 ) , LAB (mouse) ( 302 ) , LAT (mouse) ( 133 ) , MAPKAPK2 (mouse) ( 252 ) , MAPKAPK3 (mouse) ( 252 ) , MEK1 (mouse) ( 96 , 388 ) , MEKK1 (mouse) ( 32 ) , mGluR5 (mouse) ( 244 ) , MRas (human) ( 378 ) , MSK1 (human) ( 405 ) , MSK1 (mouse) ( 405 ) , MSK2 (mouse) ( 405 ) , neurogranin (mouse) ( 400 ) , NPC1 (mouse) ( 335 , 412 ) , NPM1 (human) ( 129 ) , NYAP2 (mouse) ( 68 ) , PAG (rat) ( 217 ) , PAK1 (human) ( 388 ) , PDGFRA (mouse) ( 176 ) , PDK1 (mouse) ( 227 , 320 ) , PELI1 (mouse) ( 77 ) , PKCT (mouse) ( 238 ) , PPP1CC (human) ( 203 ) , PRKD1 (mouse) ( 362 ) , PTEN (mouse) ( 25 ) , PTP1B (mouse) ( 127 ) , PTPRB (mouse) ( 127 ) , PTPRJ (mouse) ( 127 ) , PTPRM (mouse) ( 127 ) , RAB11A (mouse) ( 127 ) , Rab7 (mouse) ( 127 ) , RAC1 (mouse) ( 388 ) , RAF1 (mouse) ( 388 ) , RAIG1 (mouse) ( 115 ) , Ret (human) ( 200 , 305 ) , RHOC (mouse) ( 63 ) , ROCK1 (mouse) ( 168 ) , RSK2 (mouse) ( 255 ) , SH3BP2 (mouse) ( 294 ) , SHC1 iso2 (human) ( 290 ) , SHP-2 (mouse) ( 159 , 399 ) , SOCS1 (mouse) ( 369 ) , SOCS3 (mouse) ( 369 ) , Src (human) ( 303 ) , Src (mouse) ( 63 ) , Syk (mouse) ( 230 ) , TAK1 (mouse) ( 299 ) , TBK1 (mouse) ( 304 ) , Tel (human) ( 390 ) , TSC2 (mouse) ( 124 , 310 ) , UCP2 (mouse) ( 289 ) , VEGFR3 (mouse) ( 96 ) , Vinculin (mouse) ( 358 ) , ZAP70 (mouse) ( 230 )
Putative in vivo kinases:
MEK1 (mouse) ( 322 )
Kinases, in vitro:
MEK1 (mouse) ( 388 , 423 ) , MEK1 (rat) ( 128 )
Putative upstream phosphatases:
PPP2CA (mouse) ( 402 ) , STS-1 (mouse) ( 119 )
Phosphatases, in vitro:
STS-1 (mouse) ( 119 )
Treatments:
15d-PGJ2 ( 356 ) , 17-beta-estradiol ( 21 ) , 1Na-PP1 ( 132 ) , 22-hydroxycholesterol ( 338 ) , 5'-methylthioadenosine ( 79 ) , 8-(3-chlorostyryl) caffeine ( 258 ) , 9d ( 179 ) , A23187 ( 416 ) , acadesine ( 363 ) , adriamycin ( 110 ) , AG1478 ( 123 , 167 ) , AG490 ( 32 , 377 ) , AGEs ( 12 ) , Akt-I-1 ( 240 ) , Akt_activator_compound_11 ( 108 ) , Akt_inhibitor_VIII ( 178 ) , alloxazine ( 258 ) , alpha-lipoic_acid ( 98 ) , amino_acid_starvation ( 178 ) , amino_acids ( 178 ) , amphoterin ( 385 ) , angiopoietin-1 ( 344 ) , angiopoietin-2 ( 344 ) , anisomycin ( 252 , 405 , 416 ) , anti-CD3 ( 120 , 130 , 191 , 257 , 279 , 306 , 323 ) , anti-CD3/CD28 ( 90 , 111 , 130 , 302 ) , anti-CD4 ( 130 , 306 ) , anti-CD8 ( 306 ) , anti-CTLA-4 ( 144 ) , anti-Fas ( 199 ) , anti-IgB ( 230 ) , anti-IgE ( 159 ) , anti-IgM ( 131 , 145 ) , anti-ITGA4 ( 344 ) , anti-ITGA6 ( 344 ) , anti-ITGB3 ( 344 ) , antichymotrypsin ( 301 ) , antigenic stimulation ( 121 ) , antitrypsin ( 301 ) , aphidicolin ( 355 ) , apigenin ( 377 ) , apomorphine ( 334 ) , atorvastatin ( 258 ) , bacterial infection ( 118 ) , BAPTA-AM ( 392 , 395 , 406 ) , Bay61-3606 ( 121 ) , BDNF ( 54 , 132 , 421 ) , benzo(a)pyrene ( 280 ) , beta-amyloid_40 ( 354 ) , BFD-22 ( 10 ) , BI-D1870 ( 12 , 144 , 252 ) , BIRA766 ( 121 ) , BIRB-0796 ( 252 ) , bisindolylmaleimide ( 385 ) , bombesin ( 167 , 362 ) , bradykinin ( 22 ) , BRL37344 ( 348 ) , caffeine ( 292 ) , calphostin_C ( 385 ) , calyculin_A ( 418 ) , cAMP_analog ( 380 , 392 ) , cell_adhesion ( 182 ) , cell_detachment ( 358 ) , CGP77675 ( 364 ) , CGS_21680 ( 292 ) , chelerythrine ( 385 ) , ciclopirox_olamine ( 96 ) , cocaine ( 346 , 349 ) , cold_water_stress ( 288 ) , colforsin ( 114 , 292 , 341 , 343 , 392 , 400 ) , compound_56 ( 167 ) , ConA ( 177 ) , convulxin ( 119 ) , curcumin ( 109 ) , curdlan ( 24 ) , CXCL12 ( 251 , 391 ) , cyclic_stretch ( 123 ) , cycloheximide ( 170 ) , cytochalasin_D ( 364 ) , DDA ( 182 ) , depolarization ( 353 ) , dexamethasone ( 260 , 297 ) , DHPG ( 244 , 313 ) , differentiation ( 107 ) , DMNQ ( 203 ) , DNP ( 415 ) , DPCPX ( 258 ) , dronabinol ( 37 ) , EDTA ( 344 ) , EGF ( 22 , 32 , 99 , 114 , 115 , 169 , 255 , 256 , 278 , 296 , 297 , 309 , 341 , 348 , 355 , 357 , 362 , 374 , 376 , 388 , 398 , 399 , 401 , 405 , 410 , 413 , 414 , 418 , 422 ) , EGTA ( 170 ) , Epo ( 140 , 231 , 327 ) , epoxomicin ( 160 ) , estradiol ( 354 , 407 ) , ethanol ( 393 , 404 ) , ether ( 288 ) , faslodex ( 300 , 354 ) , fedratinib ( 231 ) , FGF1 ( 2 , 193 , 387 ) , FGF2 ( 376 , 381 , 392 ) , fibronectin ( 341 , 388 ) , fingolimod ( 36 ) , fisetin ( 38 ) , FL ( 314 ) , fluid_shear_stress ( 14 ) , food deprivation ( 288 ) , G-CSF ( 298 ) , GDNF ( 200 ) , gefitinib ( 303 ) , gelatin ( 385 ) , GF109203X ( 167 , 392 ) , GH ( 321 ) , GLP-1 ( 139 ) , glucose ( 123 , 124 , 190 , 368 , 372 ) , GM-CSF ( 245 ) , GnRH ( 40 , 254 ) , Go_6976 ( 385 ) , guanosine ( 293 ) , GW4869 ( 31 ) , H-89 ( 114 , 139 , 182 , 300 , 341 , 385 ) , H2O2 ( 120 , 123 , 290 , 333 ) , heparin sodium ( 317 ) , herstatin ( 398 ) , HGF ( 79 ) , honokiol ( 86 ) , hydroxyurea ( 322 ) , hypertonic_buffer ( 329 ) , hypoxia ( 138 , 396 ) , IBMX ( 114 , 260 , 297 , 341 , 343 ) , IFN-alpha ( 163 ) , IFN-gamma ( 293 , 377 , 408 ) , IgE ( 415 ) , IGF-1 ( 30 , 325 , 348 , 361 , 368 , 418 , 419 ) , IGF-2 ( 325 ) , IgG ( 336 ) , IL-18 ( 16 ) , IL-1b ( 337 ) , IL-3 ( 129 , 231 , 331 , 378 , 390 , 419 ) , IL-33 ( 28 ) , IL-4 ( 378 ) , IL-9 ( 378 ) , imatinib ( 129 ) , insulin ( 11 , 45 , 86 , 124 , 168 , 178 , 190 , 211 , 227 , 238 , 260 , 262 , 315 , 316 , 325 , 339 , 348 , 359 , 370 , 406 , 411 , 414 ) , ionomycin ( 77 , 120 , 295 , 418 ) , ischemia/reperfusion ( 326 ) , isoproterenol ( 348 , 380 ) , iturelix ( 254 ) , kaempferol ( 255 ) , kainic_acid ( 367 ) , KN-93 ( 254 ) , L-744,832 ( 418 ) , laminin-1 ( 385 ) , leptin ( 397 ) , levamfetamine ( 349 ) , LG268 ( 359 ) , licochalcone_A ( 171 ) , licochalcone_B ( 171 ) , licochalcone_C ( 171 ) , licochalcone_D ( 171 ) , LIF ( 318 , 351 ) , LIF withdrawal ( 13 ) , light ( 18 , 340 ) , lonafarnib ( 29 ) , long-term_potentiation ( 137 ) , low_glucose ( 123 ) , LPA ( 92 , 348 , 357 , 410 ) , LPS ( 19 , 51 , 97 , 109 , 125 , 171 , 252 , 289 , 336 , 342 , 345 , 356 , 404 ) , LY294002 ( 11 , 144 , 178 , 191 , 311 , 327 , 351 , 387 , 392 , 414 ) , M-CSF ( 263 , 294 , 389 , 402 ) , methotrexate ( 374 ) , methyl-beta-cyclodextrin ( 297 ) , MG132 ( 160 , 345 ) , midazolam ( 328 ) , MIF ( 307 ) , miR-181a ( 279 ) , MMS ( 310 ) , MPTP ( 360 ) , MRS-1523 ( 258 ) , muramyl_dipeptide ( 91 ) , NAC ( 98 ) , nicotine ( 373 ) , nifedipine ( 139 ) , NMDA ( 287 ) , nocodazole ( 355 ) , nomifensine ( 360 ) , NP68 ( 144 ) , NSC697923 ( 32 ) , NTCU ( 280 ) , OH-BBN ( 243 ) , okadaic_acid ( 303 , 416 ) , orantinib ( 305 ) , OVA ( 117 ) , PACAP ( 340 ) , palmitate ( 238 , 259 ) , Pam3CSK4 ( 252 ) , PAR1-activating_peptide ( 383 ) , PD0325901 ( 29 ) , PD169316 ( 409 ) , PD184352 ( 21 , 252 , 405 ) , PD90059 ( 300 ) , PD98059 ( 11 , 12 , 40 , 98 , 118 , 240 , 331 , 338 , 348 , 354 , 356 , 377 , 381 , 384 , 386 , 387 , 392 , 394 , 397 , 409 , 414 , 418 , 419 ) , PDGF ( 176 , 273 , 276 , 366 , 376 , 410 ) , peptones ( 395 ) , PGE2 ( 14 , 249 ) , phorbol_ester ( 77 , 170 , 252 , 295 , 321 , 357 , 364 , 392 , 400 , 405 , 410 , 416 , 418 ) , pilocarpine ( 367 ) , PKC-theta_pseudosubstrate ( 238 ) , pomegranate_wine ( 280 ) , PP1 ( 40 , 366 , 414 ) , PP2 ( 191 , 297 , 307 , 361 , 366 , 392 , 407 ) , progestin_R5020 ( 300 ) , quinpirole ( 382 ) , racepinefrine ( 275 , 380 ) , Raf1_kinase_inhibitor_I ( 240 ) , RANKL ( 294 ) , rapamycin ( 21 , 26 , 30 , 124 , 144 , 178 , 320 , 384 , 418 ) , restraint stress ( 57 ) , retinoic_acid ( 338 , 385 ) , RGD ( 344 ) , RGE ( 344 ) , rosiglitazone ( 86 , 359 ) , rottlerin ( 290 ) , S107 ( 57 ) , SB202190 ( 296 , 409 , 416 , 418 ) , SB203580 ( 170 , 252 , 364 , 405 ) , SCF ( 188 , 192 , 308 , 383 ) , seliciclib ( 353 ) , semaxanib ( 305 ) , serum ( 170 , 199 , 320 , 333 , 357 , 376 , 410 , 418 ) , serum_withdrawal ( 386 ) , silibinin ( 243 ) , silymarin ( 243 ) , siRNA ( 255 , 262 , 309 ) , SKF38393 ( 382 ) , SKF82958 ( 367 ) , SL0101 ( 252 ) , SL327 ( 334 ) , SMI11293 ( 132 ) , sorbitol ( 422 ) , SP600125 ( 361 ) , sphingomyelin ( 31 ) , sphingosine_1-phosphate ( 25 , 106 ) , SPT ( 258 ) , staurosporine ( 290 ) , streptozotocin ( 312 ) , SU5402 ( 311 ) , SU6656 ( 303 ) , sunitinib ( 305 ) , TAK1_inhibitor ( 32 ) , TCAP-1 ( 56 ) , TCDD ( 297 ) , TDZD-8 ( 141 ) , TGF-alpha ( 398 ) , TGF-beta ( 32 , 83 , 239 , 403 , 413 ) , Theophylline ( 258 ) , thrombin ( 328 , 383 ) , thrombospondin ( 350 ) , TNF ( 252 , 264 , 293 , 337 , 417 ) , triciribine ( 98 ) , TTX ( 352 ) , TUG-891 ( 8 ) , U0126 ( 48 , 56 , 83 , 96 , 109 , 120 , 124 , 139 , 144 , 163 , 170 , 178 , 182 , 200 , 230 , 240 , 256 , 258 , 261 , 297 , 308 , 311 , 321 , 322 , 333 , 343 , 351 , 353 , 354 , 383 , 385 , 386 , 387 , 392 , 401 , 416 ) , urethane ( 87 ) , UV ( 319 , 347 , 371 , 384 , 394 , 405 , 409 ) , vasopressin ( 167 , 362 ) , VEGF ( 127 ) , visual experience ( 352 ) , vitronectin ( 344 ) , WIN ( 37 ) , wortmannin ( 98 , 124 , 139 , 144 , 261 , 392 , 418 ) , XL-147 ( 1 ) , Y27632 ( 364 ) , YM-254890 ( 8 ) , Zn(2+) ( 132 ) , zymosan ( 416 )

Downstream Regulation
Effects of modification on ERK1:
activity, induced ( 65 ) , enzymatic activity, induced ( 179 , 329 , 338 , 379 , 398 , 423 )
Effects of modification on biological processes:
carcinogenesis, inhibited ( 65 ) , cell growth, inhibited ( 65 ) , transcription, altered ( 416 ) , transcription, induced ( 22 )

Disease / Diagnostics Relevance
Relevant diseases:
cancer, squamous cell carcinoma ( 142 )

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72

Ren H (2011) CST Curation Set: 12895; Year: 2011; Biosample/Treatment: /untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
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73

Ren H (2011) CST Curation Set: 12896; Year: 2011; Biosample/Treatment: /untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
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74

Ren H (2011) CST Curation Set: 12897; Year: 2011; Biosample/Treatment: /untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
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George J, et al. (2011) Resveratrol and black tea polyphenol combination synergistically suppress mouse skin tumors growth by inhibition of activated MAPKs and p53. PLoS One 6, e23395
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Smith FD, et al. (2010) AKAP-Lbc enhances cyclic AMP control of the ERK1/2 cascade. Nat Cell Biol 12, 1242-9
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Chen Y, et al. (2010) Gprc5a deletion enhances the transformed phenotype in normal and malignant lung epithelial cells by eliciting persistent Stat3 signaling induced by autocrine leukemia inhibitory factor. Cancer Res 70, 8917-26
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Wu Z, et al. (2010) MAPK phosphatase-3 promotes hepatic gluconeogenesis through dephosphorylation of forkhead box O1 in mice. J Clin Invest 120, 3901-11
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Matthews SA, et al. (2010) Unique functions for protein kinase D1 and protein kinase D2 in mammalian cells. Biochem J 432, 153-63
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Chandrakesan P, et al. (2010) Novel changes in NF-{kappa}B activity during progression and regression phases of hyperplasia: role of MEK, ERK, and p38. J Biol Chem 285, 33485-98
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Chen X, et al. (2010) Determination of the substrate specificity of protein-tyrosine phosphatase TULA-2 and identification of Syk as a TULA-2 substrate. J Biol Chem 285, 31268-76
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120

Lysechko TL, Cheung SM, Ostergaard HL (2010) Regulation of the tyrosine kinase Pyk2 by calcium is through production of reactive oxygen species in cytotoxic T lymphocytes. J Biol Chem 285, 31174-84
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121

Sanderson MP, et al. (2010) Syk and Lyn mediate distinct Syk phosphorylation events in FcɛRI-signal transduction: implications for regulation of IgE-mediated degranulation. Mol Immunol 48, 171-8
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122

Zheng Y, et al. (2010) Protein tyrosine kinase 6 directly phosphorylates AKT and promotes AKT activation in response to epidermal growth factor. Mol Cell Biol 30, 4280-92
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123

Faour WH, Thibodeau JF, Kennedy CR (2010) Mechanical stretch and prostaglandin E2 modulate critical signaling pathways in mouse podocytes. Cell Signal 22, 1222-30
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Bartolomé A, Guillén C, Benito M (2010) Role of the TSC1-TSC2 complex in the integration of insulin and glucose signaling involved in pancreatic beta-cell proliferation. Endocrinology 151, 3084-94
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Weintz G, et al. (2010) The phosphoproteome of toll-like receptor-activated macrophages. Mol Syst Biol 6, 371
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126

Wiśniewski JR, et al. (2010) Brain phosphoproteome obtained by a FASP-based method reveals plasma membrane protein topology. J Proteome Res 9, 3280-9
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Lanahan AA, et al. (2010) VEGF receptor 2 endocytic trafficking regulates arterial morphogenesis. Dev Cell 18, 713-24
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Morandell S, et al. (2010) QIKS--Quantitative identification of kinase substrates. Proteomics 10, 2015-25
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Anastasov N, et al. (2010) C/EBPbeta expression in ALK-positive anaplastic large cell lymphomas is required for cell proliferation and is induced by the STAT3 signaling pathway. Haematologica 95, 760-7
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Thien CB, et al. (2010) c-Cbl promotes T cell receptor-induced thymocyte apoptosis by activating the phosphatidylinositol 3-kinase/Akt pathway. J Biol Chem 285, 10969-81
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Damdinsuren B, et al. (2010) Single round of antigen receptor signaling programs naive B cells to receive T cell help. Immunity 32, 355-66
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132

Huang YZ, McNamara JO (2010) Mutual regulation of Src family kinases and the neurotrophin receptor TrkB. J Biol Chem 285, 8207-17
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133

Chuck MI, Zhu M, Shen S, Zhang W (2010) The role of the LAT-PLC-gamma1 interaction in T regulatory cell function. J Immunol 184, 2476-86
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134

Zhou J (2010) CST Curation Set: 9105; Year: 2010; Biosample/Treatment: cell line, F9/untreated; Disease: testicular cancer; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-102) Cat#: 9416
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135

Zhou J (2010) CST Curation Set: 9104; Year: 2010; Biosample/Treatment: cell line, ES J1/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-102) Cat#: 9416
Curated Info

136

Zhou J (2010) CST Curation Set: 9109; Year: 2010; Biosample/Treatment: cell line, P19/untreated; Disease: testicular cancer; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-102) Cat#: 9416
Curated Info

137

Racaniello M, et al. (2010) Phosphorylation changes of CaMKII, ERK1/2, PKB/Akt kinases and CREB activation during early long-term potentiation at Schaffer collateral-CA1 mouse hippocampal synapses. Neurochem Res 35, 239-46
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138

Park YK, Park H (2010) Prevention of CCAAT/enhancer-binding protein beta DNA binding by hypoxia during adipogenesis. J Biol Chem 285, 3289-99
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139

Quoyer J, et al. (2010) GLP-1 mediates antiapoptotic effect by phosphorylating Bad through a beta-arrestin 1-mediated ERK1/2 activation in pancreatic beta-cells. J Biol Chem 285, 1989-2002
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140

Liron T, Nahari T, Souroujon MC, Neumann D (2010) Insertion of an NPVY sequence into the cytosolic domain of the erythropoietin receptor selectively affects erythropoietin-mediated signalling and function. Biochem J 427, 305-12
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141

Aguilar-Morante D, et al. (2010) Inhibition of glioblastoma growth by the thiadiazolidinone compound TDZD-8. PLoS One 5, e13879
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142

Zhao L, et al. (2009) Srcasm inhibits Fyn-induced cutaneous carcinogenesis with modulation of Notch1 and p53. Cancer Res 69, 9439-47
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143

Tucker M (2009) CST Curation Set: 8602; Year: 2009; Biosample/Treatment: cell line, embryonic stem cells (mouse)(PTEN)/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: p[ST]P
Curated Info

144

Salmond RJ, Emery J, Okkenhaug K, Zamoyska R (2009) MAPK, phosphatidylinositol 3-kinase, and mammalian target of rapamycin pathways converge at the level of ribosomal protein S6 phosphorylation to control metabolic signaling in CD8 T cells. J Immunol 183, 7388-97
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145

Browne CD, et al. (2009) Suppression of phosphatidylinositol 3,4,5-trisphosphate production is a key determinant of B cell anergy. Immunity 31, 749-60
19896393   Curated Info

146

Tucker M (2009) CST Curation Set: 8084; Year: 2009; Biosample/Treatment: cell line, embryonic stem cells (mouse)(PTEN)/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

147

Tucker M (2009) CST Curation Set: 8081; Year: 2009; Biosample/Treatment: cell line, embryonic stem cells (mouse)(PTEN)/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

148

Tucker M (2009) CST Curation Set: 8088; Year: 2009; Biosample/Treatment: cell line, embryonic stem cells (mouse)(PTEN)/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

149

Tucker M (2009) CST Curation Set: 8077; Year: 2009; Biosample/Treatment: cell line, embryonic stem cells (mouse)(PTEN)/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: p[STY] Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine (P-Tyr-1000) Rabbit mAb Cat#: 8954, Phospho-Tyrosine Rabbit mAb (p-Tyr-1000) Immunoaffinity Beads Cat#: 8876
Curated Info

150

Tucker M (2009) CST Curation Set: 8085; Year: 2009; Biosample/Treatment: cell line, embryonic stem cells (mouse)(PTEN)/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

151

Tucker M (2009) CST Curation Set: 8080; Year: 2009; Biosample/Treatment: cell line, embryonic stem cells (mouse)(PTEN)/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

152

Tucker M (2009) CST Curation Set: 8072; Year: 2009; Biosample/Treatment: cell line, embryonic stem cells (mouse)(PTEN)/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: p[STY] Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine (P-Tyr-1000) Rabbit mAb Cat#: 8954, Phospho-Tyrosine Rabbit mAb (p-Tyr-1000) Immunoaffinity Beads Cat#: 8876
Curated Info

153

Guo A (2009) CST Curation Set: 8168; Year: 2009; Biosample/Treatment: tissue, testis/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: (F/Y/M)Xp[ST](L/I/M)
Curated Info

154

Guo A (2009) CST Curation Set: 8166; Year: 2009; Biosample/Treatment: tissue, spleen/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: (F/Y/M)Xp[ST](L/I/M)
Curated Info

155

Guo A (2009) CST Curation Set: 8170; Year: 2009; Biosample/Treatment: tissue, thymus/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: (F/Y/M)Xp[ST](L/I/M)
Curated Info

156

Guo A (2009) CST Curation Set: 8167; Year: 2009; Biosample/Treatment: tissue, testis/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: (F/Y/M)Xp[ST](L/I/M)
Curated Info

157

Guo A (2009) CST Curation Set: 8169; Year: 2009; Biosample/Treatment: tissue, thymus/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: (F/Y/M)Xp[ST](L/I/M)
Curated Info

158

Guo A (2009) CST Curation Set: 8165; Year: 2009; Biosample/Treatment: tissue, spleen/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: (F/Y/M)Xp[ST](L/I/M)
Curated Info

159

McPherson VA, et al. (2009) SH2 domain-containing phosphatase-2 protein-tyrosine phosphatase promotes Fc(epsilon)RI-induced activation of Fyn and Erk pathways leading to TNF(alpha) release from bone marrow-derived mast cells. J Immunol 183, 4940-7
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160

Santamaría E, et al. (2009) Regulation of stathmin phosphorylation in mouse liver progenitor-29 cells during proteasome inhibition. Proteomics 9, 4495-506
19688729   Curated Info

161

Guo A (2009) CST Curation Set: 7709; Year: 2009; Biosample/Treatment: tissue, testis/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

162

Guo A (2009) CST Curation Set: 7708; Year: 2009; Biosample/Treatment: tissue, spleen/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

163

Joshi S, et al. (2009) Type I interferon (IFN)-dependent activation of Mnk1 and its role in the generation of growth inhibitory responses. Proc Natl Acad Sci U S A 106, 12097-102
19574459   Curated Info

164

Zhou J (2009) CST Curation Set: 7383; Year: 2009; Biosample/Treatment: tissue, brain/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: QXp[ST]
Curated Info

165

Possemato A (2009) CST Curation Set: 7168; Year: 2009; Biosample/Treatment: cell line, RAW 264.7/LPS; Disease: leukemia; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

166

Possemato A (2009) CST Curation Set: 7167; Year: 2009; Biosample/Treatment: cell line, RAW 264.7/LPS; Disease: leukemia; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

167

Sinnett-Smith J, et al. (2009) Protein Kinase D Mediates Mitogenic Signaling by Gq-coupled Receptors through Protein Kinase C-independent Regulation of Activation Loop Ser744 and Ser748 Phosphorylation. J Biol Chem 284, 13434-45
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168

Lee DH, et al. (2009) Targeted disruption of ROCK1 causes insulin resistance in vivo. J Biol Chem 284, 11776-80
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169

Chung BM, et al. (2009) The role of cooperativity with Src in oncogenic transformation mediated by non-small cell lung cancer-associated EGF receptor mutants. Oncogene 28, 1821-32
19305428   Curated Info

170

Tucker DE, et al. (2009) Role of Phosphorylation and Basic Residues in the Catalytic Domain of Cytosolic Phospholipase A2{alpha} in Regulating Interfacial Kinetics and Binding and Cellular Function. J Biol Chem 284, 9596-611
19176526   Curated Info

171

Furusawa J, et al. (2009) Glycyrrhiza inflata-derived chalcones, Licochalcone A, Licochalcone B and Licochalcone D, inhibit phosphorylation of NF-kappaB p65 in LPS signaling pathway. Int Immunopharmacol 9, 499-507
19291859   Curated Info

172

Li Y (2009) CST Curation Set: 6297; Year: 2009; Biosample/Treatment: cell line, MEF/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

173

Li Y (2009) CST Curation Set: 6299; Year: 2009; Biosample/Treatment: cell line, MEF Ras v12/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

174

Li Y (2009) CST Curation Set: 6296; Year: 2009; Biosample/Treatment: cell line, MEF/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
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175

Catalanotti F, et al. (2009) A Mek1-Mek2 heterodimer determines the strength and duration of the Erk signal. Nat Struct Mol Biol 16, 294-303
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176

Olson LE, Soriano P (2009) Increased PDGFRalpha activation disrupts connective tissue development and drives systemic fibrosis. Dev Cell 16, 303-13
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177

Das M, et al. (2009) Induction of hepatitis by JNK-mediated expression of TNF-alpha. Cell 136, 249-60
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178

van Gorp AG, et al. (2009) AGC kinases regulate phosphorylation and activation of eukaryotic translation initiation factor 4B. Oncogene 28, 95-106
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Tallent MK, et al. (2009) In vivo modulation of O-GlcNAc levels regulates hippocampal synaptic plasticity through interplay with phosphorylation. J Biol Chem 284, 174-81
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180

McPherson VA, et al. (2009) Contributions of F-BAR and SH2 domains of Fes protein tyrosine kinase for coupling to the FcepsilonRI pathway in mast cells. Mol Cell Biol 29, 389-401
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181

Lorenz K, Schmitt JP, Schmitteckert EM, Lohse MJ (2009) A new type of ERK1/2 autophosphorylation causes cardiac hypertrophy. Nat Med 15, 75-83
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182

Conche C, Boulla G, Trautmann A, Randriamampita C (2009) T cell adhesion primes antigen receptor-induced calcium responses through a transient rise in adenosine 3',5'-cyclic monophosphate. Immunity 30, 33-43
19144315   Curated Info

183

Zanivan S, et al. (2008) Solid tumor proteome and phosphoproteome analysis by high resolution mass spectrometry. J Proteome Res 7, 5314-26
19367708   Curated Info

184

Stokes M (2008) CST Curation Set: 5664; Year: 2008; Biosample/Treatment: tissue, heart/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

185

Stokes M (2008) CST Curation Set: 5665; Year: 2008; Biosample/Treatment: tissue, heart/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

186

Stokes M (2008) CST Curation Set: 5666; Year: 2008; Biosample/Treatment: cell line, Noonan Syndrome mouse heart/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

187

Stokes M (2008) CST Curation Set: 5667; Year: 2008; Biosample/Treatment: cell line, Noonan Syndrome mouse heart/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

188

Simon C, et al. (2008) Lnk adaptor protein down-regulates specific Kit-induced signaling pathways in primary mast cells. Blood 112, 4039-47
18753636   Curated Info

189

Kaneda T, et al. (2008) Mutation of Y925F in focal adhesion kinase (FAK) suppresses melanoma cell proliferation and metastasis. Cancer Lett 270, 354-61
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190

Mariappan MM, et al. (2008) Glycogen synthase kinase 3beta is a novel regulator of high glucose- and high insulin-induced extracellular matrix protein synthesis in renal proximal tubular epithelial cells. J Biol Chem 283, 30566-75
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191

Bécart S, et al. (2008) Tyrosine-phosphorylation-dependent translocation of the SLAT protein to the immunological synapse is required for NFAT transcription factor activation. Immunity 29, 704-19
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192

Samayawardhena LA, Pallen CJ (2008) Protein-tyrosine phosphatase alpha regulates stem cell factor-dependent c-Kit activation and migration of mast cells. J Biol Chem 283, 29175-85
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193

Partovian C, et al. (2008) Syndecan-4 regulates subcellular localization of mTOR Complex2 and Akt activation in a PKCalpha-dependent manner in endothelial cells. Mol Cell 32, 140-9
18851840   Curated Info

194

Rikova K (2008) CST Curation Set: 5291; Year: 2008; Biosample/Treatment: cell line, Dana Farber-S1/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: p[ST]Q
Curated Info

195

Rikova K (2008) CST Curation Set: 5292; Year: 2008; Biosample/Treatment: cell line, Dana Farber-S2/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: p[ST]Q
Curated Info

196

Rikova K (2008) CST Curation Set: 5293; Year: 2008; Biosample/Treatment: cell line, Dana Farber-S3/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: p[ST]Q
Curated Info

197

Rikova K (2008) CST Curation Set: 5296; Year: 2008; Biosample/Treatment: cell line, Dana Farber-KTL(LN)-4/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: p[ST]Q
Curated Info

198

Mertins P, et al. (2008) Investigation of protein-tyrosine phosphatase 1B function by quantitative proteomics. Mol Cell Proteomics 7, 1763-77
18515860   Curated Info

199

Noble C, et al. (2008) CRAF autophosphorylation of serine 621 is required to prevent its proteasome-mediated degradation. Mol Cell 31, 862-72
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200

Encinas M, et al. (2008) Analysis of Ret knockin mice reveals a critical role for IKKs, but not PI 3-K, in neurotrophic factor-induced survival of sympathetic neurons. Cell Death Differ 15, 1510-21
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201

Hermann-Kleiter N, et al. (2008) The nuclear orphan receptor NR2F6 suppresses lymphocyte activation and T helper 17-dependent autoimmunity. Immunity 29, 205-16
18701084   Curated Info

202

Rikova K (2008) CST Curation Set: 4985; Year: 2008; Biosample/Treatment: tissue, lung/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

203

Tchivilev I, et al. (2008) Identification of a protective role for protein phosphatase 1cgamma1 against oxidative stress-induced vascular smooth muscle cell apoptosis. J Biol Chem 283, 22193-205
18540044   Curated Info

204

Luo W, et al. (2008) Global impact of oncogenic Src on a phosphotyrosine proteome. J Proteome Res 7, 3447-60
18563927   Curated Info

205

Rikova K (2008) CST Curation Set: 4790; Year: 2008; Biosample/Treatment: cell line, Dana Farber-KT-1/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

206

Rikova K (2008) CST Curation Set: 4771; Year: 2008; Biosample/Treatment: cell line, Dana Farber-KTL-1/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

207

Rikova K (2008) CST Curation Set: 4839; Year: 2008; Biosample/Treatment: cell line, Dana Farber-S1/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

208

Rikova K (2008) CST Curation Set: 4840; Year: 2008; Biosample/Treatment: cell line, Dana Farber-S2/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

209

Rikova K (2008) CST Curation Set: 4763; Year: 2008; Biosample/Treatment: cell line, Dana Farber-S1/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

210

Rikova K (2008) CST Curation Set: 4765; Year: 2008; Biosample/Treatment: cell line, Dana Farber-S2/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

211

Cha HC, et al. (2008) Phosphorylation of CCAAT/enhancer-binding protein alpha regulates GLUT4 expression and glucose transport in adipocytes. J Biol Chem 283, 18002-11
18408001   Curated Info

212

Li Y (2008) CST Curation Set: 4544; Year: 2008; Biosample/Treatment: cell line, 10T1/2/FGF; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

213

Li Y (2008) CST Curation Set: 4543; Year: 2008; Biosample/Treatment: cell line, 10T1/2/FGF; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

214

Li Y (2008) CST Curation Set: 4542; Year: 2008; Biosample/Treatment: cell line, 10T1/2/FGF; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

215

Rikova K (2008) CST Curation Set: 4476; Year: 2008; Biosample/Treatment: cell line, MD Ander 1158(393P)/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

216

Rikova K (2008) CST Curation Set: 4481; Year: 2008; Biosample/Treatment: cell line, MD Ander a0859/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

217

Oneyama C, et al. (2008) The lipid raft-anchored adaptor protein Cbp controls the oncogenic potential of c-Src. Mol Cell 30, 426-36
18498747   Curated Info

218

Rikova K (2008) CST Curation Set: 4477; Year: 2008; Biosample/Treatment: cell line, MD Ander 1154/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

219

Rikova K (2008) CST Curation Set: 4478; Year: 2008; Biosample/Treatment: cell line, MD Ander 0895/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

220

Rikova K (2008) CST Curation Set: 4479; Year: 2008; Biosample/Treatment: cell line, MD Ander 1202(344SQ)/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

221

Rikova K (2008) CST Curation Set: 4480; Year: 2008; Biosample/Treatment: cell line, MD Ander 1249/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

222

Rikova K (2008) CST Curation Set: 4474; Year: 2008; Biosample/Treatment: cell line, MD Ander 393LN/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

223

Rikova K (2008) CST Curation Set: 4437; Year: 2008; Biosample/Treatment: tissue, lung/untreated; Disease: non-small cell lung cancer; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

224

Rikova K (2008) CST Curation Set: 4438; Year: 2008; Biosample/Treatment: tissue, lung/untreated; Disease: non-small cell lung cancer; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

225

Rikova K (2008) CST Curation Set: 4439; Year: 2008; Biosample/Treatment: tissue, lung/untreated; Disease: non-small cell lung cancer; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

226

Rikova K (2008) CST Curation Set: 4440; Year: 2008; Biosample/Treatment: tissue, lung/untreated; Disease: non-small cell lung cancer; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

227

Bayascas JR, et al. (2008) Mutation of the PDK1 PH domain inhibits protein kinase B/Akt, leading to small size and insulin resistance. Mol Cell Biol 28, 3258-72
18347057   Curated Info

228

Ren H (2008) CST Curation Set: 4335; Year: 2008; Biosample/Treatment: cell line, EGFR_WT/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

229

Ren H (2008) CST Curation Set: 4337; Year: 2008; Biosample/Treatment: cell line, Ras_WT/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

230

Yasuda T, et al. (2008) Erk kinases link pre-B cell receptor signaling to transcriptional events required for early B cell expansion. Immunity 28, 499-508
18356083   Curated Info

231

Wernig G, et al. (2008) Efficacy of TG101348, a selective JAK2 inhibitor, in treatment of a murine model of JAK2V617F-induced polycythemia vera. Cancer Cell 13, 311-20
18394554   Curated Info

232

Rikova K (2008) CST Curation Set: 4249; Year: 2008; Biosample/Treatment: tissue, lung/untreated; Disease: non-small cell lung cancer; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

233

Rikova K (2008) CST Curation Set: 4250; Year: 2008; Biosample/Treatment: tissue, lung/Tarceva; Disease: non-small cell lung cancer; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

234

Rikova K (2008) CST Curation Set: 4251; Year: 2008; Biosample/Treatment: tissue, lung/untreated; Disease: non-small cell lung cancer; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

235

Rikova K (2008) CST Curation Set: 4252; Year: 2008; Biosample/Treatment: tissue, lung/untreated; Disease: non-small cell lung cancer; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

236

Rikova K (2008) CST Curation Set: 4253; Year: 2008; Biosample/Treatment: tissue, lung/Tarceva; Disease: non-small cell lung cancer; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

237

Rikova K (2008) CST Curation Set: 4254; Year: 2008; Biosample/Treatment: tissue, lung/untreated; Disease: non-small cell lung cancer; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

238

Bakker W, et al. (2008) Protein kinase C theta activation induces insulin-mediated constriction of muscle resistance arteries. Diabetes 57, 706-13
18086904   Curated Info

239

Samarakoon R, Higgins SP, Higgins CE, Higgins PJ (2008) TGF-beta1-induced plasminogen activator inhibitor-1 expression in vascular smooth muscle cells requires pp60(c-src)/EGFR(Y845) and Rho/ROCK signaling. J Mol Cell Cardiol 44, 527-38
18255094   Curated Info

240

Alejandro EU, Johnson JD (2008) Inhibition of Raf-1 alters multiple downstream pathways to induce pancreatic beta-cell apoptosis. J Biol Chem 283, 2407-17
18006502   Curated Info

241

Takatori A, et al. (2008) Differential transmission of MEKK1 morphogenetic signals by JNK1 and JNK2. Development 135, 23-32
18032450   Curated Info

242

Ballif BA, Carey GR, Sunyaev SR, Gygi SP (2008) Large-scale identification and evolution indexing of tyrosine phosphorylation sites from murine brain. J Proteome Res 7, 311-8
18034455   Curated Info

243

Tyagi A, et al. (2007) Chemopreventive effects of silymarin and silibinin on N-butyl-N-(4-hydroxybutyl) nitrosamine induced urinary bladder carcinogenesis in male ICR mice. Mol Cancer Ther 6, 3248-55
18089718   Curated Info

244

Hu HJ, et al. (2007) Metabotropic glutamate receptor 5 modulates nociceptive plasticity via extracellular signal-regulated kinase-Kv4.2 signaling in spinal cord dorsal horn neurons. J Neurosci 27, 13181-91
18045912   Curated Info

245

Ramshaw HS, et al. (2007) The Shc-binding site of the {beta}c subunit of the GM-CSF/IL-3/IL-5 receptors is a negative regulator of hematopoiesis. Blood 110, 3582-90
17638849   Curated Info

246

Cao L, et al. (2007) Quantitative time-resolved phosphoproteomic analysis of mast cell signaling. J Immunol 179, 5864-76
17947660   Curated Info

247

Gu T (2007) CST Curation Set: 3404; Year: 2007; Biosample/Treatment: cell line, Baf3(MSCV-NEO-FLT3/ITD)/IL3 withdrawal; Disease: chronic myelogenous leukemia; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

248

Gu T (2007) CST Curation Set: 3405; Year: 2007; Biosample/Treatment: cell line, Baf3(MSCV-NEO-FLT3/ITD)/IL3 withdrawal; Disease: chronic myelogenous leukemia; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

249

Schenning M, van Tiel CM, Wirtz KW, Snoek GT (2007) The anti-apoptotic MAP kinase pathway is inhibited in NIH3T3 fibroblasts with increased expression of phosphatidylinositol transfer protein beta. Biochim Biophys Acta 1773, 1664-71
17683809   Curated Info

250

Robinson MJ, et al. (2007) Phosphorylation of TPL-2 on serine 400 is essential for lipopolysaccharide activation of extracellular signal-regulated kinase in macrophages. Mol Cell Biol 27, 7355-64
17709378   Curated Info

251

Le Y, et al. (2007) SOCS3 protein developmentally regulates the chemokine receptor CXCR4-FAK signaling pathway during B lymphopoiesis. Immunity 27, 811-23
18031698   Curated Info

252

Zaru R, et al. (2007) The MAPK-activated kinase Rsk controls an acute Toll-like receptor signaling response in dendritic cells and is activated through two distinct pathways. Nat Immunol 8, 1227-35
17906627   Curated Info

253

Yu J (2007) CST Curation Set: 3380; Year: 2007; Biosample/Treatment: cell line, Mouse Mesenchymal Stem Cells/bFGF; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

254

Yamanaka A, et al. (2007) Involvement of CaM kinase II in gonadotropin-releasing hormone-induced activation of MAP kinase in cultured hypothalamic neurons. Arch Biochem Biophys 466, 234-41
17706588   Curated Info

255

Cho YY, et al. (2007) Ribosomal S6 kinase 2 is a key regulator in tumor promoter induced cell transformation. Cancer Res 67, 8104-12
17804722   Curated Info

256

Falin RA, Cotton CU (2007) Acute downregulation of ENaC by EGF involves the PY motif and putative ERK phosphorylation site. J Gen Physiol 130, 313-28
17724164   Curated Info

257

McNeill L, et al. (2007) The differential regulation of Lck kinase phosphorylation sites by CD45 is critical for T cell receptor signaling responses. Immunity 27, 425-37
17719247   Curated Info

258

Merla R, et al. (2007) The central role of adenosine in statin-induced ERK1/2, Akt, and eNOS phosphorylation. Am J Physiol Heart Circ Physiol 293, H1918-28
17616749   Curated Info

259

Jaeschke A, Davis RJ (2007) Metabolic stress signaling mediated by mixed-lineage kinases. Mol Cell 27, 498-508
17679097   Curated Info

260

Li X, et al. (2007) Role of cdk2 in the sequential phosphorylation/activation of C/EBPbeta during adipocyte differentiation. Proc Natl Acad Sci U S A 104, 11597-602
17601773   Curated Info

261

Dong S, et al. (2007) 14-3-3 Integrates prosurvival signals mediated by the AKT and MAPK pathways in ZNF198-FGFR1-transformed hematopoietic cells. Blood 110, 360-9
17389761   Curated Info

262

Yoshizaki T, et al. (2007) Myosin 5a is an insulin-stimulated Akt2 (protein kinase Bbeta) substrate modulating GLUT4 vesicle translocation. Mol Cell Biol 27, 5172-83
17515613   Curated Info

263

Takeshita S, et al. (2007) c-Fms tyrosine 559 is a major mediator of M-CSF-induced proliferation of primary macrophages. J Biol Chem 282, 18980-90
17420255   Curated Info

264

Schlaepfer DD, et al. (2007) Tumor necrosis factor-alpha stimulates focal adhesion kinase activity required for mitogen-activated kinase-associated interleukin 6 expression. J Biol Chem 282, 17450-9
17438336   Curated Info

265

Guo A (2007) CST Curation Set: 2987; Year: 2007; Biosample/Treatment: tissue, liver/-; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

266

Guo A (2007) CST Curation Set: 2988; Year: 2007; Biosample/Treatment: tissue, liver/-; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

267

Guo A (2007) CST Curation Set: 2989; Year: 2007; Biosample/Treatment: tissue, liver/Insulin; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

268

Guo A (2007) CST Curation Set: 2990; Year: 2007; Biosample/Treatment: tissue, liver/Insulin; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

269

Guo A (2007) CST Curation Set: 2983; Year: 2007; Biosample/Treatment: tissue, liver/-; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

270

Guo A (2007) CST Curation Set: 2984; Year: 2007; Biosample/Treatment: tissue, liver/-; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

271

Guo A (2007) CST Curation Set: 2985; Year: 2007; Biosample/Treatment: tissue, liver/Insulin; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

272

Guo A (2007) CST Curation Set: 2986; Year: 2007; Biosample/Treatment: tissue, liver/Insulin; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

273

Artemenko Y, Gagnon A, Ibrahim S, Sorisky A (2007) Regulation of PDGF-stimulated SHIP2 tyrosine phosphorylation and association with Shc in 3T3-L1 preadipocytes. J Cell Physiol 211, 598-607
17219406   Curated Info

274

Guo A (2007) CST Curation Set: 2923; Year: 2007; Biosample/Treatment: tissue, heart/-; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: p[ST](D/E)X(D/E) Antibodies Used to Purify Peptides prior to LCMS: Phospho(Ser/Thr) CKII Substrate Antibody (polyAb) Cat#: 5808, PTMScan(R) Phospho-CK Substrate Motif (S*/T*D/EXD/E) Immunoaffinity Beads Cat#: 1994
Curated Info

275

Toole BJ, Cohen PT (2007) The skeletal muscle-specific glycogen-targeted protein phosphatase 1 plays a major role in the regulation of glycogen metabolism by adrenaline in vivo. Cell Signal 19, 1044-55
17257813   Curated Info

276

Xing K, et al. (2007) Low molecular weight protein tyrosine phosphatase (LMW-PTP) and its possible physiological functions of redox signaling in the eye lens. Biochim Biophys Acta 1774, 545-55
17428749   Curated Info

277

Guo A (2007) CST Curation Set: 2827; Year: 2007; Biosample/Treatment: tissue, heart/-; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

278

Jo M, et al. (2007) Urokinase receptor primes cells to proliferate in response to epidermal growth factor. Oncogene 26, 2585-94
17043637   Curated Info

279

Li QJ, et al. (2007) miR-181a is an intrinsic modulator of T cell sensitivity and selection. Cell 129, 147-61
17382377   Curated Info

280

Khan N, et al. (2007) Oral consumption of pomegranate fruit extract inhibits growth and progression of primary lung tumors in mice. Cancer Res 67, 3475-82
17389758   Curated Info

281

Guo A (2007) CST Curation Set: 2672; Year: 2007; Biosample/Treatment: tissue, brain/-; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

282

Guo A (2007) CST Curation Set: 2675; Year: 2007; Biosample/Treatment: tissue, brain/LY; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

283

Guo A (2007) CST Curation Set: 2677; Year: 2007; Biosample/Treatment: tissue, brain/-; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: p[ST]Q Antibodies Used to Purify Peptides prior to LCMS: Phospho-(Ser/Thr) ATM/ATR Substrate Antibody Cat#: 2851
Curated Info

284

Guo A (2007) CST Curation Set: 2682; Year: 2007; Biosample/Treatment: tissue, brain/-; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: p[ST]Q Antibodies Used to Purify Peptides prior to LCMS: Phospho-(Ser/Thr) ATM/ATR Substrate Antibody Cat#: 2851
Curated Info

285

Guo A (2007) CST Curation Set: 2564; Year: 2007; Biosample/Treatment: cell line, C2C12-D/-; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

286

Guo A (2007) CST Curation Set: 2565; Year: 2007; Biosample/Treatment: cell line, C2C12-D/Insulin; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

287

Cuthbert PC, et al. (2007) Synapse-associated protein 102/dlgh3 couples the NMDA receptor to specific plasticity pathways and learning strategies. J Neurosci 27, 2673-82
17344405   Curated Info

288

Ikeda Y, Ishiguro K, Fujita SC (2007) Ether stress-induced Alzheimer-like tau phosphorylation in the normal mouse brain. FEBS Lett 581, 891-7
17289030   Curated Info

289

Emre Y, et al. (2007) Mitochondria contribute to LPS-induced MAPK activation via uncoupling protein UCP2 in macrophages. Biochem J 402, 271-8
17073824   Curated Info

290

Hu Y, Kang C, Philp RJ, Li B (2007) PKC delta phosphorylates p52ShcA at Ser29 to regulate ERK activation in response to H2O2. Cell Signal 19, 410-8
16963224   Curated Info

291

Villén J, Beausoleil SA, Gerber SA, Gygi SP (2007) Large-scale phosphorylation analysis of mouse liver. Proc Natl Acad Sci U S A 104, 1488-93
17242355   Curated Info

292

Sahin B, et al. (2007) Evaluation of neuronal phosphoproteins as effectors of caffeine and mediators of striatal adenosine A2A receptor signaling. Brain Res 1129, 1-14
17157277   Curated Info

293

D'Alimonte I, et al. (2007) Guanosine inhibits CD40 receptor expression and function induced by cytokines and beta amyloid in mouse microglia cells. J Immunol 178, 720-31
17202332   Curated Info

294

Ueki Y, et al. (2007) Increased myeloid cell responses to M-CSF and RANKL cause bone loss and inflammation in SH3BP2 "cherubism" mice. Cell 128, 71-83
17218256   Curated Info

295

Blonska M, et al. (2007) The CARMA1-Bcl10 signaling complex selectively regulates JNK2 kinase in the T cell receptor-signaling pathway. Immunity 26, 55-66
17189706   Curated Info

296

Frey MR, Dise RS, Edelblum KL, Polk DB (2006) p38 kinase regulates epidermal growth factor receptor downregulation and cellular migration. EMBO J 25, 5683-92
17139251   Curated Info

297

Liu X, Jefcoate C (2006) 2,3,7,8-tetrachlorodibenzo-p-dioxin and epidermal growth factor cooperatively suppress peroxisome proliferator-activated receptor-gamma1 stimulation and restore focal adhesion complexes during adipogenesis: selective contributions of Src, Rho, and Erk distinguish these overlapping processes in C3H10T1/2 cells. Mol Pharmacol 70, 1902-15
16971554   Curated Info

298

Chen C, et al. (2006) The Integrin alpha9beta1 contributes to granulopoiesis by enhancing granulocyte colony-stimulating factor receptor signaling. Immunity 25, 895-906
17137800   Curated Info

299

Xie M, et al. (2006) A pivotal role for endogenous TGF-beta-activated kinase-1 in the LKB1/AMP-activated protein kinase energy-sensor pathway. Proc Natl Acad Sci U S A 103, 17378-83
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