Lys326
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Home > Ubiquitylation Site Page: > Lys326  -  IKKG (human)

Site Information
REkLAEkkELLQEQL   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 7482002

In vivo Characterization
Methods used to characterize site in vivo:
mass spectrometry ( 1 ) , mutation of modification site ( 2 ) , western blotting ( 2 )
Disease tissue studied:
lymphoma ( 2 ) , B cell lymphoma ( 2 )
Relevant cell line - cell type - tissue:
1.3E2 (B lymphocyte) ( 2 ) , 293 (epithelial) ( 2 ) , HEp-2 (squamous) ( 1 ) , Jurkat (T lymphocyte) ( 1 )

Downstream Regulation
Effects of modification on biological processes:
signaling pathway regulation ( 2 )

References 

1

Akimov V, et al. (2018) UbiSite approach for comprehensive mapping of lysine and N-terminal ubiquitination sites. Nat Struct Mol Biol 25, 631-640
29967540   Curated Info

2

Sebban-Benin H, et al. (2007) Identification of TRAF6-dependent NEMO polyubiquitination sites through analysis of a new NEMO mutation causing incontinentia pigmenti. Hum Mol Genet 16, 2805-15
17728323   Curated Info