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Phosphorylation Site Page:
Ser100 - YB-1 (rat)

Site Information
NPRKYLRsVGDGETV   SwissProt Entrez-Gene
Predicted information:  Scansite
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 455636

In vivo Characterization
Methods used to characterize site in vivo: immunoprecipitation (1), mass spectrometry (2), mutation of modification site (1), phospho-antibody (1), western blotting (1)
Relevant cell line - cell type - tissue: 'kidney, inner medulla' (2), granulosa (1)

Controlled by
Treatments: 8-CPT-2Me-cAMP (1), BI-D1870 (1), cAMP_analog (1), EGF (1), forskolin (1), FSH (1), IGF-1 (1), PD98059 (1), tautomycin (1), wortmannin (1)

Downstream Regulation
Effects of modification on YB-1: intracellular localization (1)
Effects of modification on biological processes: transcription, induced (1)



Donaubauer EM, Hunzicker-Dunn ME (2016) Extracellular Signal-regulated Kinase (ERK)-dependent Phosphorylation of Y-Box-binding Protein 1 (YB-1) Enhances Gene Expression in Granulosa Cells in Response to Follicle-stimulating Hormone (FSH). J Biol Chem 291, 12145-60
27080258   Curated Info


Hoffert JD, et al. (2006) Quantitative phosphoproteomics of vasopressin-sensitive renal cells: regulation of aquaporin-2 phosphorylation at two sites. Proc Natl Acad Sci U S A 103, 7159-64
16641100   Curated Info

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