Ser6

Site Information
__MEPDNsPRKIQFT SwissProt Entrez-Gene
Blast this site against: NCBI SwissProt PDB
Site Group ID: 478275

In vivo Characterization
Methods used to characterize site in vivo:	mass spectrometry ( 1 ) , phospho-antibody ( 2 )
Relevant cell line - cell type - tissue:	'brain, cerebellum' ( 1 ) , 'brain, cerebral cortex' ( 1 , 2 ) , 'brain, hippocampus' ( 2 ) , 'brain, striatum' ( 2 ) , adipose tissue ( 1 ) , kidney ( 1 ) , muscle ( 1 ) , PC-12 (chromaffin) ( 2 )

Upstream Regulation
Putative in vivo kinases:	CDK5 (mouse) ( 2 )
Kinases, in vitro:	CDK5 (human) ( 2 )
Putative upstream phosphatases:	PPP1CA (mouse) ( 2 ) , PPP2R5A (mouse) ( 2 )
Treatments:	butyrolactone ( 2 ) , ciclosporin ( 2 ) , colforsin ( 2 ) , fostriecin ( 2 ) , indolinone_A ( 2 ) , indolinone_B ( 2 ) , neurabin ( 2 ) , NMDA ( 2 ) , okadaic_acid ( 2 ) , seliciclib ( 2 ) , U0126 ( 2 )

References
1	Lundby A, et al. (2012) Quantitative maps of protein phosphorylation sites across 14 different rat organs and tissues. Nat Commun 3, 876 22673903 Curated Info
2	Nguyen C, et al. (2007) Regulation of protein phosphatase inhibitor-1 by cyclin-dependent kinase 5. J Biol Chem 282, 16511-20 17400554 Curated Info