Lys275
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Home > Acetylation Site Page: > Lys275  -  BACE (human)

Site Information
EINGQDLkMDCkEYN   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 478257

In vivo Characterization
Methods used to characterize site in vivo:
[14C] acetate labeling ( 1 ) , immunoprecipitation ( 1 ) , mass spectrometry (in vitro) ( 1 ) , mutation of modification site ( 1 ) , western blotting ( 1 )
Disease tissue studied:
neuroblastoma ( 1 )
Relevant cell line - cell type - tissue:

Downstream Regulation
Effects of modification on BACE:
intracellular localization ( 1 ) , protein stabilization ( 1 )

References 

1

Costantini C, Ko MH, Jonas MC, Puglielli L (2007) A reversible form of lysine acetylation in the ER and Golgi lumen controls the molecular stabilization of BACE1. Biochem J 407, 383-95
17425515   Curated Info