Ser114
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Home > Phosphorylation Site Page: > Ser114  -  p21Cip1 (human)

Site Information
EEDHVDLsLSCTLVP   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 478191

In vivo Characterization
Methods used to characterize site in vivo:
mutation of modification site ( 1 )
Relevant cell line - cell type - tissue:

Upstream Regulation
Putative in vivo kinases:
GSK3B (human) ( 1 )
Kinases, in vitro:
GSK3B (human) ( 1 )
Treatments:
caffeine ( 1 ) , lithium ( 1 ) , siRNA ( 1 ) , TDZD-8 ( 1 ) , UV ( 1 )

Downstream Regulation
Effects of modification on p21Cip1:
protein degradation ( 1 )

References 

1

Lee JY, et al. (2007) Glycogen synthase kinase 3beta phosphorylates p21WAF1/CIP1 for proteasomal degradation after UV irradiation. Mol Cell Biol 27, 3187-98
17283049   Curated Info