Thr135
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Home > Phosphorylation Site Page: > Thr135  -  IRF3 (human)

Site Information
GGGSTSDtQEDILDE   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 477901

In vivo Characterization
Methods used to characterize site in vivo:
immunoprecipitation ( 1 ) , mutation of modification site ( 1 ) , phospho-antibody ( 1 ) , western blotting ( 1 )
Relevant cell line - cell type - tissue:

Upstream Regulation
Putative in vivo kinases:
DNAPK (human) ( 1 )
Kinases, in vitro:
DNAPK (human) ( 1 )
Treatments:
dsDNA ( 1 ) , virus infection ( 1 )

Downstream Regulation
Effects of modification on IRF3:
intracellular localization ( 1 ) , protein stabilization ( 1 )

References 

1

Karpova AY, et al. (2002) Interferon regulatory factor-3 is an in vivo target of DNA-PK. Proc Natl Acad Sci U S A 99, 2818-23
11867762   Curated Info