Tyr129
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Home > Phosphorylation Site Page: > Tyr129  -  profilin 1 (cow)

Site Information
GMINKKCyEMASHLR   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 450514

In vivo Characterization
Methods used to characterize site in vivo:
immunoprecipitation ( 1 ) , phospho-antibody ( 1 ) , western blotting ( 1 )
Relevant cell line - cell type - tissue:
BAEC (endothelial) ( 1 ) , endothelial-aorta ( 1 ) , HUVEC (endothelial) ( 1 )

Upstream Regulation
Putative in vivo kinases:
Src (human) ( 1 ) , VEGFR2 (human) ( 1 )
Treatments:
VEGF ( 1 )

Downstream Regulation
Effects of modification on profilin 1:
molecular association, regulation ( 1 )
Effects of modification on biological processes:
cell motility, induced ( 1 )
Induce interaction with:
ACTB (cow) ( 1 )

References 

1

Fan Y, et al. (2012) Stimulus-dependent phosphorylation of profilin-1 in angiogenesis. Nat Cell Biol 14, 1046-56
23000962   Curated Info