Arg633

Site Information
MEQMGGrrGGrGGPG SwissProt Entrez-Gene
Blast this site against: NCBI SwissProt PDB
Site Group ID: 476735

In vivo Characterization
Methods used to characterize site in vivo:	mass spectrometry ( 1 , 3 , 4 ) , mass spectrometry (in vitro) ( 2 )
Disease tissue studied:	cervical cancer ( 3 ) , cervical adenocarcinoma ( 3 ) , leukemia ( 4 ) , T cell leukemia ( 4 )
Relevant cell line - cell type - tissue:	HeLa S3 (cervical) ( 3 ) , Jurkat (T lymphocyte) ( 1 , 4 ) , mononuclear-blood ( 4 ) , T lymphocyte ( 1 )

References
1	Geoghegan V, et al. (2015) Comprehensive identification of arginine methylation in primary T cells reveals regulatory roles in cell signalling. Nat Commun 6, 6758 25849564 Curated Info
2	Pahlich S, et al. (2005) Different methylation characteristics of protein arginine methyltransferase 1 and 3 toward the Ewing Sarcoma protein and a peptide. Proteins 61, 164-75 16044463 Curated Info
3	Ong SE, Mittler G, Mann M (2004) Identifying and quantifying in vivo methylation sites by heavy methyl SILAC. Nat Methods 1, 119-26 15782174 Curated Info
4	Belyanskaya LL, Gehrig PM, Gehring H (2001) Exposure on cell surface and extensive arginine methylation of ewing sarcoma (EWS) protein. J Biol Chem 276, 18681-7 11278906 Curated Info