Thr235
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Home > Phosphorylation Site Page: > Thr235  -  Ezrin (mouse)

Site Information
YEKDDKLtPkIGFPW   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 449293

In vivo Characterization
Methods used to characterize site in vivo:
[32P] bio-synthetic labeling ( 1 ) , mutation of modification site ( 1 ) , phospho-antibody ( 1 )
Relevant cell line - cell type - tissue:
IMR-90 (fibroblast) ( 1 ) , Saos-2 (bone cell) ( 1 )

Upstream Regulation
Putative in vivo kinases:
CDK5 (mouse) ( 1 )
Kinases, in vitro:
CDK5 (mouse) ( 1 )
Treatments:
seliciclib ( 1 )

Downstream Regulation
Effects of modification on Ezrin:
activity, induced ( 1 ) , intracellular localization ( 1 )
Effects of modification on biological processes:
cytoskeletal reorganization ( 1 )

References 

1

Yang HS, Hinds PW (2003) Increased ezrin expression and activation by CDK5 coincident with acquisition of the senescent phenotype. Mol Cell 11, 1163-76
12769842   Curated Info