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Site Information |
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AATkIQAsFRGHITR SwissProt Entrez-Gene |
Blast this site against: NCBI SwissProt PDB |
Site Group ID: 448719 |
In vivo Characterization | |
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Methods used to characterize site in vivo: | |
Disease tissue studied: | |
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Downstream Regulation | |
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References | |
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Nguyen L, He Q, Meiri KF (2009) Regulation of GAP-43 at serine 41 acts as a switch to modulate both intrinsic and extrinsic behaviors of growing neurons, via altered membrane distribution. Mol Cell Neurosci 41, 62-73
19249369 Curated Info |
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Gopalakrishna R, Gundimeda U, Schiffman JE, McNeill TH (2008) A direct redox regulation of protein kinase C isoenzymes mediates oxidant-induced neuritogenesis in PC12 cells. J Biol Chem 283, 14430-44
18375950 Curated Info |
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Kim HJ, et al. (2006) Acute ethanol administration decreases GAP-43 and phosphorylated-GAP-43 in the rat hippocampus. Brain Res 1112, 16-25
16904654 Curated Info |
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Tejero-Díez P, Rodríguez-Sánchez P, Martín-Cófreces NB, Díez-Guerra FJ (2000) bFGF stimulates GAP-43 phosphorylation at ser41 and modifies its intracellular localization in cultured hippocampal neurons. Mol Cell Neurosci 16, 766-80
11124896 Curated Info |
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Edgar MA, et al. (1997) Phosphorylation of the casein kinase II domain of B-50 (GAP-43) in rat cortical growth cones. J Neurochem 69, 2206-15
9349568 Curated Info |
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He Q, Dent EW, Meiri KF (1997) Modulation of actin filament behavior by GAP-43 (neuromodulin) is dependent on the phosphorylation status of serine 41, the protein kinase C site. J Neurosci 17, 3515-24
9133376 Curated Info |
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Meiri KF, Beverly M (1994) Effects of gangliosides GM1 and GD1a on GAP-43 phosphorylation and dephosphorylation in isolated growth cones. J Neurochem 62, 291-9
8263528 Curated Info |
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Spencer SA, Schuh SM, Liu WS, Willard MB (1992) GAP-43, a protein associated with axon growth, is phosphorylated at three sites in cultured neurons and rat brain. J Biol Chem 267, 9059-64
1533624 Curated Info |
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Meiri KF, Burdick D (1991) Nerve growth factor stimulation of GAP-43 phosphorylation in intact isolated growth cones. J Neurosci 11, 3155-64
1834809 Curated Info |
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Nielander HB, et al. (1990) Mutation of serine 41 in the neuron-specific protein B-50 (GAP-43) prohibits phosphorylation by protein kinase C. J Neurochem 55, 1442-5
2144585 Curated Info |