Lys50

Site Information
NLLsVAykNVVGARR SwissProt Entrez-Gene
Blast this site against: NCBI SwissProt PDB
Site Group ID: 474722

In vivo Characterization
Methods used to characterize site in vivo:	mass spectrometry ( 2 )
Relevant cell line - cell type - tissue:	MEF (fibroblast) [HDAC6 (mouse), heterozygous knockout] ( 2 )

Downstream Regulation
Effects of modification on 14-3-3 gamma:	molecular association, regulation ( 1 )
Induce interaction with:	STAR (mouse) ( 1 )

References
1	Aghazadeh Y, Ye X, Blonder J, Papadopoulos V (2014) Protein modifications regulate the role of 14-3-3γ adaptor protein in cAMP-induced steroidogenesis in MA-10 Leydig cells. J Biol Chem 289, 26542-53 25086053 Curated Info
2	Li Y (2006) CST Curation Set: 1907; Year: 2006; Biosample/Treatment: cell line, MEF[HDAC6(heterozygous knockout)]/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: acK Antibodies Used to Purify Peptides prior to LCMS: Acetylated-Lysine (Ac-K2-100) Rabbit mAb Cat#: 9814, PTMScan(R) Acetyl-Lys Motif (Ac-K) Immunoaffinity Beads Cat#: 1989 Curated Info

References

Aghazadeh Y, Ye X, Blonder J, Papadopoulos V (2014) Protein modifications regulate the role of 14-3-3γ adaptor protein in cAMP-induced steroidogenesis in MA-10 Leydig cells. J Biol Chem 289, 26542-53
25086053 Curated Info

Li Y (2006) CST Curation Set: 1907; Year: 2006; Biosample/Treatment: cell line, MEF[HDAC6(heterozygous knockout)]/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: acK Antibodies Used to Purify Peptides prior to LCMS: Acetylated-Lysine (Ac-K2-100) Rabbit mAb Cat#: 9814, PTMScan(R) Acetyl-Lys Motif (Ac-K) Immunoaffinity Beads Cat#: 1989
Curated Info