Thr1146

Site Information
MsVyPMQtEHHQtPL SwissProt Entrez-Gene
Blast this site against: NCBI SwissProt PDB
Site Group ID: 474534
Available spectra: 1 CST

In vivo Characterization
Methods used to characterize site in vivo:	mass spectrometry ( 1 , 2 , 3 , 4 , 5 , 6 , 7 , 8 )
Disease tissue studied:	lung cancer ( 1 , 2 , 3 ) , non-small cell lung cancer ( 1 , 2 , 3 ) , non-small cell lung adenocarcinoma ( 1 , 2 , 3 ) , non-small cell large cell lung carcinoma ( 1 , 3 )
Relevant cell line - cell type - tissue:	Calu-3 (pulmonary) ( 2 ) , HCC78 (pulmonary) ( 3 ) , HCC827 (pulmonary) ( 2 ) , HeLa (cervical) ( 8 ) , HeLa_NOC (cervical) ( 7 ) , Jurkat (T lymphocyte) ( 4 , 5 ) , lung ( 1 , 2 , 3 ) , NCI-H1299 (pulmonary) ( 1 ) , NCI-H1650 (pulmonary) ( 2 ) , NCI-H1734 (pulmonary) ( 1 ) , NCI-H1781 (pulmonary) ( 3 ) , NCI-H1944 (pulmonary) ( 1 ) , NCI-H1975 (pulmonary) ( 2 ) , NCI-H2106 (pulmonary) ( 2 ) , NCI-H2228 (pulmonary) ( 3 ) , NCI-H3122 (pulmonary) ( 3 ) , NCI-H358 (pulmonary) ( 1 ) , NCI-H460 (pulmonary) ( 1 ) , NCI-H661 (pulmonary) ( 3 )

Upstream Regulation
Treatments:	BI_4834 ( 7 ) , hesperadin ( 7 ) , MG132 ( 7 ) , nocodazole ( 7 )

References
1	Rikova K, Hall B (2013) CST Curation Set: 20737, 21164, 30161, 30162, 30163; Year: 2013; Biosample/Treatment: cell line, H1299, H1944, H358, H1734, H460; Disease: -; TMT: Y; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY, p[ST], RXXp[ST], pSQ, p[ST]QG, LXRXXp[ST], p[ST]P Curated Info
2	Rikova K, Hall B (2013) CST Curation Set: 20738, 21165, 30164, 30165, 30166; Year: 2013; Biosample/Treatment: cell line, H1650, HCC827, H1975, Calu-3, H2106; Disease: -; TMT: Y; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY, p[ST], RXXp[ST], pSQ, p[ST]QG, LXRXXp[ST], p[ST]P Curated Info
3	Rikova K, Hall B (2013) CST Curation Set: 20740, 21167, 30170, 30171, 30172; Year: 2013; Biosample/Treatment: cell line, H2228, H3122, HCC78, H661, H1781; Disease: -; TMT: Y; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY, p[ST], RXXp[ST], pSQ, p[ST]QG, LXRXXp[ST], p[ST]P Curated Info
4	Mulhern D (2012) CST Curation Set: 13107; Year: 2012; Biosample/Treatment: cell line, Jurkat/calyculin_A & pervanadate; Disease: T cell leukemia; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: p[STY]) Curated Info
5	Mulhern D (2011) CST Curation Set: 13106; Year: 2011; Biosample/Treatment: cell line, Jurkat/calyculin_A & pervanadate; Disease: T cell leukemia; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: p[STY]) Curated Info
6	Rikova K (2011) CST Curation Set: 13123; Year: 2011; Biosample/Treatment: cell line, MGH-1/unknown; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: p[STY]) Curated Info
7	Hegemann B, et al. (2011) Systematic phosphorylation analysis of human mitotic protein complexes. Sci Signal 4, rs12 22067460 Curated Info
8	Hauf S, et al. (2005) Dissociation of cohesin from chromosome arms and loss of arm cohesion during early mitosis depends on phosphorylation of SA2. PLoS Biol 3, e69 15737063 Curated Info