Ser5
Javascript is not enabled on this browser. This site will not work properly without Javascript.
PhosphoSitePlus Homepage PhosphoSitePlus® v6.7.9
Powered by Cell Signaling Technology
Home > Phosphorylation Site Page: > Ser5  -  HEC1 (human)

Site Information
___MKRSsVsSGGAG   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 474510

In vivo Characterization
Methods used to characterize site in vivo:
immunoprecipitation ( 1 ) , mass spectrometry ( 1 ) , mutation of modification site ( 1 )
Relevant cell line - cell type - tissue:
HeLa (cervical) ( 1 )

Upstream Regulation
Kinases, in vitro:
AurB (human) ( 2 )
Treatments:
nocodazole ( 1 )

Downstream Regulation
Effects of modification on biological processes:
cell cycle regulation ( 1 , 2 )

References 

1

Sobajima T, et al. (2023) PP6 regulation of Aurora A-TPX2 limits NDC80 phosphorylation and mitotic spindle size. J Cell Biol 222
36897279   Curated Info

2

DeLuca JG, et al. (2006) Kinetochore microtubule dynamics and attachment stability are regulated by Hec1. Cell 127, 969-82
17129782   Curated Info

Developed with grants from  NIH Logo and literature mining with Linguamatics  I2E Logo Creative Commons License PhosphoSite, created by Cell Signaling Technology is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 3.0 Unported License.

©2003-2024 Cell Signaling Technology, Inc.