Ser1224
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Home > Phosphorylation Site Page: > Ser1224  -  STAG2 (human)

Site Information
PAsIMDEsVLGVsMF   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 474506

In vivo Characterization
Methods used to characterize site in vivo:
immunoprecipitation ( 1 , 7 ) , mass spectrometry ( 2 , 3 , 4 , 5 , 6 , 8 ) , phospho-antibody ( 1 , 7 ) , western blotting ( 1 )
Disease tissue studied:
gastric cancer ( 6 ) , gastric carcinoma ( 6 )
Relevant cell line - cell type - tissue:
HeLa (cervical) ( 1 , 7 , 8 ) , HeLa_NOC (cervical) ( 5 ) , Jurkat (T lymphocyte) ( 2 , 3 , 4 ) , MKN-45 (gastric) ( 6 )

Upstream Regulation
Treatments:
BI_4834 ( 5 ) , hesperadin ( 5 ) , MG132 ( 5 ) , nocodazole ( 1 , 5 ) , thymidine ( 1 )

References 

1

Liu H, Rankin S, Yu H (2013) Phosphorylation-enabled binding of SGO1-PP2A to cohesin protects sororin and centromeric cohesion during mitosis. Nat Cell Biol 15, 40-9
23242214   Curated Info

2

Guo A (2011) CST Curation Set: 12018; Year: 2011; Biosample/Treatment: cell line, Jurkat/calyculin_A & pervanadate; Disease: T cell leukemia; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: p[ST]P
Curated Info

3

Guo A (2011) CST Curation Set: 12021; Year: 2011; Biosample/Treatment: cell line, Jurkat/calyculin_A & pervanadate; Disease: T cell leukemia; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: p[ST]P
Curated Info

4

Guo A (2011) CST Curation Set: 12022; Year: 2011; Biosample/Treatment: cell line, Jurkat/calyculin_A & pervanadate; Disease: T cell leukemia; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: p[ST]P
Curated Info

5

Hegemann B, et al. (2011) Systematic phosphorylation analysis of human mitotic protein complexes. Sci Signal 4, rs12
22067460   Curated Info

6

Moritz A (2010) CST Curation Set: 9234; Year: 2010; Biosample/Treatment: cell line, MKN-45/calyculin_A & pervanadate; Disease: gastric carcinoma; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: p[STY])
Curated Info

7

Kueng S, et al. (2006) Wapl controls the dynamic association of cohesin with chromatin. Cell 127, 955-67
17113138   Curated Info

8

Hauf S, et al. (2005) Dissociation of cohesin from chromosome arms and loss of arm cohesion during early mitosis depends on phosphorylation of SA2. PLoS Biol 3, e69
15737063   Curated Info

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