Ser489
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Home > Phosphorylation Site Page: > Ser489  -  WAVE2 (human)

Site Information
sDsEDDssEFDEDDW   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 6377640

In vivo Characterization
Methods used to characterize site in vivo:
[32P] bio-synthetic labeling ( 2 ) , electrophoretic mobility shift ( 2 ) , mass spectrometry ( 1 ) , mutation of modification site ( 2 ) , phospho-antibody ( 2 ) , western blotting ( 2 )
Relevant cell line - cell type - tissue:

Upstream Regulation
Kinases, in vitro:
CK2A1 (human) ( 2 )

Downstream Regulation
Effects of modification on WAVE2:
activity, inhibited ( 2 )
Effects of modification on biological processes:
cytoskeletal reorganization ( 2 )

References 

1

Guo A (2011) CST Curation Set: 11287; Year: 2011; Biosample/Treatment: cell line, Jurkat/calyculin_A & pervanadate; Disease: T cell leukemia; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: p[ST]P Antibodies Used to Purify Peptides prior to LCMS: Phospho-Thr-Pro Motif Antibody (polyAB) Cat#: 3003, PTMScan(R) Phospho-Thr-Pro Motif (T*P) Immunoaffinity Beads Cat#: 1996
Curated Info

2

Pocha SM, Cory GO (2009) WAVE2 is regulated by multiple phosphorylation events within its VCA domain. Cell Motil Cytoskeleton 66, 36-47
19012317   Curated Info